12 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNX4	Sorting nexin 4. (450 aa)
	TF	Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa)
	IKBKB	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. (763 aa)
	SNX2	Sorting nexin 2. (519 aa)
	RGMA	Repulsive guidance molecule BMP co-receptor a. (458 aa)
	LOC100610002	IKBKG isoform 9. (401 aa)
	ENSPTRP00000079019	annotation not available (165 aa)
	HFE	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (760 aa)
	HJV	HFE2 isoform 1. (426 aa)
	SNX1	Sorting nexin 1. (557 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	IKBKB	ENSPTRP00000084209	ENSPTRP00000034600	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	0.999
CHUK	IKBKG	ENSPTRP00000084209	ENSPTRP00000082387	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
CHUK	LOC100610002	ENSPTRP00000084209	ENSPTRP00000076480	Component of inhibitor of nuclear factor kappa B kinase complex.	IKBKG isoform 9.	0.991
ENSPTRP00000079019	HFE	ENSPTRP00000079019	ENSPTRP00000079201	annotation not available	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.	0.779
HFE	ENSPTRP00000079019	ENSPTRP00000079201	ENSPTRP00000079019	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.	annotation not available	0.779
HFE	HJV	ENSPTRP00000079201	ENSPTRP00000085910	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.	HFE2 isoform 1.	0.922
HFE	TF	ENSPTRP00000079201	ENSPTRP00000026561	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.	Serotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity).	0.480
HJV	HFE	ENSPTRP00000085910	ENSPTRP00000079201	HFE2 isoform 1.	Hereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.	0.922
IKBKB	CHUK	ENSPTRP00000034600	ENSPTRP00000084209	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKB	IKBKG	ENSPTRP00000034600	ENSPTRP00000082387	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.999
IKBKB	LOC100610002	ENSPTRP00000034600	ENSPTRP00000076480	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	IKBKG isoform 9.	0.990
IKBKG	CHUK	ENSPTRP00000082387	ENSPTRP00000084209	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.999
IKBKG	IKBKB	ENSPTRP00000082387	ENSPTRP00000034600	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	0.999
IKBKG	LOC100610002	ENSPTRP00000082387	ENSPTRP00000076480	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	IKBKG isoform 9.	0.544
LOC100610002	CHUK	ENSPTRP00000076480	ENSPTRP00000084209	IKBKG isoform 9.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.991
LOC100610002	IKBKB	ENSPTRP00000076480	ENSPTRP00000034600	IKBKG isoform 9.	Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta.	0.990
LOC100610002	IKBKG	ENSPTRP00000076480	ENSPTRP00000082387	IKBKG isoform 9.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.544
SNX1	SNX2	ENSPTRP00000093339	ENSPTRP00000048102	Sorting nexin 1.	Sorting nexin 2.	0.995
SNX1	SNX4	ENSPTRP00000093339	ENSPTRP00000026413	Sorting nexin 1.	Sorting nexin 4.	0.828
SNX2	SNX1	ENSPTRP00000048102	ENSPTRP00000093339	Sorting nexin 2.	Sorting nexin 1.	0.995