Your Input: | |
| | ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19. (804 aa) |
| | TACSTD2 | Tumor associated calcium signal transducer 2. (324 aa) |
| | VANGL1 | Vang-like protein. (524 aa) |
| | VANGL2 | Vang-like protein. (521 aa) |
| | CD34 | CD34 isoform 1. (328 aa) |
| | AGT | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa) |
| | DKK1 | Dickkopf-like protein 1. (289 aa) |
| | STOX1 | STOX1 isoform 1. (887 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | JHY | C11orf63 isoform 1. (778 aa) |
| | HOXC11 | HOXC11 isoform 1. (304 aa) |
| | NTN4 | NTN4 isoform 3. (628 aa) |
| | GPC6 | GPC6 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa) |
| | PAX9 | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. (347 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (836 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (268 aa) |
| | SOX8 | SOX8 isoform 1. (446 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | FZD2 | FZD2 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa) |
| | SP6 | Sp6 transcription factor. (376 aa) |
| | NGFR | Nerve growth factor receptor. (427 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | MKS1 | MKS transition zone complex subunit 1. (559 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SIX2 | SIX homeobox 2. (291 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | SPEF1 | Sperm flagellar 1. (236 aa) |
| | BMP2 | Bone morphogenetic protein 2. (398 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | TIAM1 | T-cell lymphoma invasion and metastasis 1. (1591 aa) |
| | TBX1 | TBX1 isoform 1. (478 aa) |
| | ZNRF3 | ZNRF3 isoform 1. (920 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | RYK | Receptor like tyrosine kinase. (610 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | SEC24B | SEC24B isoform 1. (1286 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (295 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | EDN1 | EDN1 isoform 1. (212 aa) |
| | PKHD1 | PKHD1 isoform 1. (4074 aa) |
| | RSPO3 | RSPO3 isoform 1. (292 aa) |
| | AHI1 | Abelson helper integration site 1. (1196 aa) |
| | HOXA11 | HOXA11 isoform 2. (313 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1283 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | SMO | SMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | TNFRSF11B | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (428 aa) |
| | DMRT3 | Doublesex and mab-3 related transcription factor 3. (472 aa) |
| | ROR2 | Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa) |
| | GPC4 | GPC4 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | FZD6 | Frizzled homolog 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | SIX4 | SIX homeobox 4. (781 aa) |
| | CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (757 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (228 aa) |
| | APCDD1 | Adenomatosis polyposis coli down-regulated 1. (514 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (470 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | LHX1 | LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa) |
| | MSX1 | Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa) |
| | CELSR1 | CELSR1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (2998 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | CK820_G0012168 | ABL1 isoform 3. (1149 aa) |
| | MLLT3 | MLLT3 isoform 1. (570 aa) |
| | ENSPTRP00000063199 | annotation not available (456 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | ENSPTRP00000063703 | annotation not available (362 aa) |
| | RSPO2 | R-spondin 2 homolog. (243 aa) |
| | ENSPTRP00000064416 | annotation not available (502 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa) |
| | PRICKLE2 | Prickle planar cell polarity protein 2. (900 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (569 aa) |
| | SAPCD2 | SAPCD2 isoform 1. (394 aa) |
| | SMO-2 | Smoothened, frizzled class receptor. (786 aa) |
| | ENSPTRP00000067675 | annotation not available (357 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | PLEKHA4 | Pleckstrin homology domain containing, family A (Phosphoinositide binding specific) member 4. (779 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (585 aa) |
| | SIX1 | SIX homeobox 1. (284 aa) |
| | DAB2 | Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (812 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | ENSPTRP00000073424 | annotation not available (357 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (901 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] (743 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | WNT9B-2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | AR | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. (912 aa) |
| | ENSPTRP00000077262 | annotation not available (314 aa) |
| | DAAM1 | Dishevelled associated activator of morphogenesis 1. (1078 aa) |
| | CDC42 | Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa) |
| | MAGED1 | MAGE family member D1. (834 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (727 aa) |
| | CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3322 aa) |
| | AJAP1 | Adherens junctions associated protein 1. (411 aa) |
| | BMP4-2 | Bone morphogenetic protein 4. (408 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | SPRY1 | Sprouty homolog 1, antagonist of FGF signaling. (319 aa) |
| | GRHL3 | Grainyhead like transcription factor 3. (626 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RAC1-2 | Rac family small GTPase 1. (212 aa) |
| | ENSPTRP00000084871 | annotation not available (456 aa) |
| | MED12 | Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifi [...] (2182 aa) |
| | PAX8 | PAX8 isoform 1. (456 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | CELSR2 | CELSR2 isoform 1; Belongs to the G-protein coupled receptor 2 family. (2925 aa) |
| | ROR1 | Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (945 aa) |
| | BTBD7 | BTB (POZ) domain containing 7. (1132 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa) |
| | WT1 | WT1 transcription factor. (514 aa) |
| | FZD1 | FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa) |
| | PRICKLE1 | PRICKLE1 isoform 11. (831 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (744 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) |
| | PAX2 | PAX2 isoform 1. (417 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | FZD1-2 | Frizzled class receptor 1. (580 aa) |
| | ENSPTRP00000093474 | Cadherin EGF LAG seven-pass G-type receptor 1. (124 aa) |
| | LGR4 | LGR4 isoform 2. (951 aa) |
