5 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (408 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (891 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)
	TBX3	T-box transcription factor 3. (743 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMPR2	ENSPTRP00000010780	ENSPTRP00000048858	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.877
BMP4	TBX3	ENSPTRP00000010780	ENSPTRP00000084833	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.403
BMP4-2	BMPR2	ENSPTRP00000080656	ENSPTRP00000048858	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.877
BMP4-2	TBX3	ENSPTRP00000080656	ENSPTRP00000084833	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.403
BMPR2	BMP4	ENSPTRP00000048858	ENSPTRP00000010780	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.877
BMPR2	BMP4-2	ENSPTRP00000048858	ENSPTRP00000080656	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.877
TBX3	BMP4	ENSPTRP00000084833	ENSPTRP00000010780	T-box transcription factor 3.	Bone morphogenetic protein 4.	0.403
TBX3	BMP4-2	ENSPTRP00000084833	ENSPTRP00000080656	T-box transcription factor 3.	Bone morphogenetic protein 4.	0.403