9 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	PIM1	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (535 aa)
	CK820_G0046635	NACA isoform 1. (1839 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (500 aa)
	ENSPTRP00000084090	annotation not available (121 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP4	ENSPTRP00000078228	ENSPTRP00000010780	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.505
BMP10	BMP4-2	ENSPTRP00000078228	ENSPTRP00000080656	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.505
BMP10	SMAD4	ENSPTRP00000078228	ENSPTRP00000017047	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.455
BMP4	BMP10	ENSPTRP00000010780	ENSPTRP00000078228	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.505
BMP4	SMAD4	ENSPTRP00000010780	ENSPTRP00000017047	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.853
BMP4	SOX9	ENSPTRP00000010780	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
BMP4-2	BMP10	ENSPTRP00000080656	ENSPTRP00000078228	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.505
BMP4-2	SMAD4	ENSPTRP00000080656	ENSPTRP00000017047	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.853
BMP4-2	SOX9	ENSPTRP00000080656	ENSPTRP00000016293	Bone morphogenetic protein 4.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.509
RBPJ	SMAD4	ENSPTRP00000079413	ENSPTRP00000017047	Recombination signal binding protein for immunoglobulin kappa J region.	Mothers against decapentaplegic homolog.	0.459
SMAD4	BMP10	ENSPTRP00000017047	ENSPTRP00000078228	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 10.	0.455
SMAD4	BMP4	ENSPTRP00000017047	ENSPTRP00000010780	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.853
SMAD4	BMP4-2	ENSPTRP00000017047	ENSPTRP00000080656	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.853
SMAD4	RBPJ	ENSPTRP00000017047	ENSPTRP00000079413	Mothers against decapentaplegic homolog.	Recombination signal binding protein for immunoglobulin kappa J region.	0.459
SMAD4	SOX9	ENSPTRP00000017047	ENSPTRP00000016293	Mothers against decapentaplegic homolog.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.511
SOX9	BMP4	ENSPTRP00000016293	ENSPTRP00000010780	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Bone morphogenetic protein 4.	0.509
SOX9	BMP4-2	ENSPTRP00000016293	ENSPTRP00000080656	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Bone morphogenetic protein 4.	0.509
SOX9	SMAD4	ENSPTRP00000016293	ENSPTRP00000017047	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Mothers against decapentaplegic homolog.	0.511