Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACVR1B | CTNNB1 | ENSPTRP00000008474 | ENSPTRP00000044466 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.414 |
| ACVR1B | INHBA | ENSPTRP00000008474 | ENSPTRP00000093770 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Inhibin subunit beta A. | 0.978 |
| ACVR1B | INHBB | ENSPTRP00000008474 | ENSPTRP00000090910 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Inhibin subunit beta B. | 0.807 |
| ACVR1B | SMURF2 | ENSPTRP00000008474 | ENSPTRP00000088535 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | E3 ubiquitin-protein ligase. | 0.627 |
| AGO2 | SRY | ENSPTRP00000035263 | ENSPTRP00000038745 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is responsible for initiating male sex determination. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending (By similarity). | 0.554 |
| AR | CTNNB1 | ENSPTRP00000076864 | ENSPTRP00000044466 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.960 |
| AR | HDAC2 | ENSPTRP00000076864 | ENSPTRP00000049696 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. | 0.586 |
| AR | P2RY1 | ENSPTRP00000076864 | ENSPTRP00000026760 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. | 0.400 |
| AR | SOX9 | ENSPTRP00000076864 | ENSPTRP00000016293 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.412 |
| AR | SRC | ENSPTRP00000076864 | ENSPTRP00000076797 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Tyrosine-protein kinase. | 0.911 |
| AR | SRY | ENSPTRP00000076864 | ENSPTRP00000038745 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is responsible for initiating male sex determination. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending (By similarity). | 0.476 |
| AURKA | CDC25A | ENSPTRP00000023475 | ENSPTRP00000076630 | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | Cell division cycle 25 homolog A. | 0.512 |
| AURKA | CDC25B | ENSPTRP00000023475 | ENSPTRP00000041347 | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | Cell division cycle 25 homolog B. | 0.476 |
| AURKA | CDC25C | ENSPTRP00000023475 | ENSPTRP00000047041 | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | CDC25C isoform 7. | 0.595 |
| AURKA | CTNNB1 | ENSPTRP00000023475 | ENSPTRP00000044466 | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.493 |
| AURKA | ENSPTRP00000092743 | ENSPTRP00000023475 | ENSPTRP00000092743 | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | annotation not available | 0.544 |
| BHMG1 | STRA8 | ENSPTRP00000060485 | ENSPTRP00000033793 | BHMG1 isoform 1. | Stimulated by retinoic acid 8. | 0.589 |
| C1QBP | CTNNB1 | ENSPTRP00000014729 | ENSPTRP00000044466 | Complement component 1, q subcomponent binding protein. | Catenin (Cadherin-associated protein), beta 1, 88kDa. | 0.464 |
| CDC25A | AURKA | ENSPTRP00000076630 | ENSPTRP00000023475 | Cell division cycle 25 homolog A. | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. | 0.512 |
| CDC25A | CDC25B | ENSPTRP00000076630 | ENSPTRP00000041347 | Cell division cycle 25 homolog A. | Cell division cycle 25 homolog B. | 0.531 |
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