STRINGSTRING
CSF3 CSF3 CCL27 CCL27 STAP1 STAP1 FES FES HRAS HRAS NRP1 NRP1 HAX1 HAX1 HCLS1 HCLS1 BAIAP2L2 BAIAP2L2 NTF3 NTF3 BAIAP2L1-2 BAIAP2L1-2 NTRK3 NTRK3 HCK HCK ENSPTRP00000085116 ENSPTRP00000085116 CDK5 CDK5 CDC42 CDC42 ABL1 ABL1 BCAS3 BCAS3 TEK TEK BAIAP2 BAIAP2 ENSPTRP00000062048 ENSPTRP00000062048 CK820_G0012168 CK820_G0012168 BAIAP2L1 BAIAP2L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF3Colony stimulating factor 3 (Granulocyte). (204 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
BAIAP2L2BAIAP2L2 isoform 1. (518 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa)
BAIAP2L1-2BAR/IMD domain containing adaptor protein 2 like 1. (502 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa)
HCKTyrosine-protein kinase. (526 aa)
ENSPTRP00000085116annotation not available (227 aa)
CDK5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (950 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
ENSPTRP00000062048annotation not available (257 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
BAIAP2L1BAI1-associated protein 2-like 1. (511 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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