STRINGSTRING
IL6-2 IL6-2 CK820_G0040570-2 CK820_G0040570-2 CK820_G0040570 CK820_G0040570 DENND1B DENND1B CD81 CD81 IL6 IL6 GATA3 GATA3 RSAD2 RSAD2 NLRP3 NLRP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6-2Interleukin 6. (234 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
DENND1BDENN domain containing 1B. (775 aa)
CD81CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] (303 aa)
IL6Interleukin 6 (Interferon, beta 2). (234 aa)
GATA3GATA binding protein 3. (444 aa)
RSAD2RSAD2 isoform 1. (361 aa)
NLRP3NLRP3 isoform 2. (1025 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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