STRINGSTRING
IGF1 IGF1 ENSPTRP00000065244 ENSPTRP00000065244 FOXC1 FOXC1 ENSPTRP00000064832 ENSPTRP00000064832 GATA3 GATA3 H1-0 H1-0 HAND2 HAND2 NIBAN2 NIBAN2 TWIST1 TWIST1 CTNNB1 CTNNB1 DDRGK1 DDRGK1 KLF4 KLF4 POU4F2 POU4F2 EP300 EP300 TGFB1 TGFB1 RB1 RB1 IFNG IFNG TRAF6 TRAF6 PARP1 PARP1 LAMTOR5 LAMTOR5 GTF2B GTF2B POU4F1 POU4F1 ENSPTRP00000085888 ENSPTRP00000085888 IL32 IL32 PARK7 PARK7 ENSPTRP00000075929 ENSPTRP00000075929 IL32-2 IL32-2 ENSPTRP00000070902 ENSPTRP00000070902 PAX6 PAX6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF1Insulin-like growth factor 1 (Somatomedin C). (196 aa)
ENSPTRP00000065244annotation not available (463 aa)
FOXC1FOXC1 isoform 1. (550 aa)
ENSPTRP00000064832annotation not available (85 aa)
GATA3GATA binding protein 3. (444 aa)
H1-0H1F0 isoform 1. (194 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
NIBAN2FAM129B isoform 2. (746 aa)
TWIST1TWIST1 isoform 2. (163 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
DDRGK1DDRGK domain containing 1. (314 aa)
KLF4Kruppel-like factor 4 (Gut). (479 aa)
POU4F2POU domain protein. (406 aa)
EP300E1A binding protein p300. (2175 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
RB1RB transcriptional corepressor 1. (928 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa)
GTF2BGeneral transcription factor IIB. (310 aa)
POU4F1POU domain protein. (350 aa)
ENSPTRP00000085888annotation not available (71 aa)
IL32IL32 isoform 28. (225 aa)
PARK7PARK7 isoform 1. (189 aa)
ENSPTRP00000075929annotation not available (130 aa)
IL32-2IL32 isoform 12. (193 aa)
ENSPTRP00000070902annotation not available (168 aa)
PAX6PAX6 isoform 13. (436 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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