16 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	SOX6	SOX6 isoform 9. (828 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	KAT2A	Histone acetyltransferase KAT2A isoform X1. (837 aa)
	MYOCD	MYOCD isoform 2. (986 aa)
	ARRB2	ARRB2 isoform 2. (430 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	EFNB2	EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
	DKK1	Dickkopf-like protein 1. (289 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (521 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	BMP4-2	Bone morphogenetic protein 4. (408 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB2	FZD7	ENSPTRP00000014687	ENSPTRP00000088268	ARRB2 isoform 2.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.429
ARRB2	TGFB1	ENSPTRP00000014687	ENSPTRP00000018930	ARRB2 isoform 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.498
BMP2	BMP4	ENSPTRP00000022701	ENSPTRP00000010780	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.951
BMP2	BMP4-2	ENSPTRP00000022701	ENSPTRP00000080656	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.530
BMP2	DKK1	ENSPTRP00000022701	ENSPTRP00000004327	Bone morphogenetic protein 2.	Dickkopf-like protein 1.	0.581
BMP2	SMAD4	ENSPTRP00000022701	ENSPTRP00000017047	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.874
BMP2	TGFB1	ENSPTRP00000022701	ENSPTRP00000018930	Bone morphogenetic protein 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.548
BMP2	WNT3A	ENSPTRP00000022701	ENSPTRP00000051074	Bone morphogenetic protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.574
BMP4	BMP2	ENSPTRP00000010780	ENSPTRP00000022701	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.951
BMP4	DKK1	ENSPTRP00000010780	ENSPTRP00000004327	Bone morphogenetic protein 4.	Dickkopf-like protein 1.	0.566
BMP4	SMAD4	ENSPTRP00000010780	ENSPTRP00000017047	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.853
BMP4	WNT3A	ENSPTRP00000010780	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
BMP4-2	BMP2	ENSPTRP00000080656	ENSPTRP00000022701	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.530
BMP4-2	DKK1	ENSPTRP00000080656	ENSPTRP00000004327	Bone morphogenetic protein 4.	Dickkopf-like protein 1.	0.566
BMP4-2	SMAD4	ENSPTRP00000080656	ENSPTRP00000017047	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.853
BMP4-2	WNT3A	ENSPTRP00000080656	ENSPTRP00000051074	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.708
DKK1	BMP2	ENSPTRP00000004327	ENSPTRP00000022701	Dickkopf-like protein 1.	Bone morphogenetic protein 2.	0.581
DKK1	BMP4	ENSPTRP00000004327	ENSPTRP00000010780	Dickkopf-like protein 1.	Bone morphogenetic protein 4.	0.566
DKK1	BMP4-2	ENSPTRP00000004327	ENSPTRP00000080656	Dickkopf-like protein 1.	Bone morphogenetic protein 4.	0.566
DKK1	FZD7	ENSPTRP00000004327	ENSPTRP00000088268	Dickkopf-like protein 1.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.422