STRINGSTRING
HSPA9 HSPA9 BBS12 BBS12 YAP1 YAP1 ZFP36 ZFP36 TMSB4X-2 TMSB4X-2 JAG1 JAG1 STAT3 STAT3 EZH2-2 EZH2-2 PRICKLE1 PRICKLE1 YTHDF2 YTHDF2 HNRNPU HNRNPU TBX3 TBX3 GSK3B GSK3B HES5-2 HES5-2 LOC459970 LOC459970 EZH2 EZH2 LBH LBH ENSPTRP00000069497 ENSPTRP00000069497 CDK12 CDK12 ZFP36L2 ZFP36L2 N4BP2L2 N4BP2L2 NFE2L2 NFE2L2 ESRRB ESRRB HES1 HES1 TCF15 TCF15 WNT3A WNT3A TMSB4X TMSB4X NELFB NELFB HES5 HES5 REST REST NOTCH1 NOTCH1 CDK13 CDK13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
BBS12BBS12 isoform 1. (710 aa)
YAP1Yes-associated protein 1. (508 aa)
ZFP36Zinc finger protein 36, C3H type, homolog. (332 aa)
TMSB4X-2Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (54 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
PRICKLE1PRICKLE1 isoform 11. (831 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (595 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U (Scaffold attachment factor A). (825 aa)
TBX3T-box transcription factor 3. (743 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (481 aa)
HES5-2Hes family bHLH transcription factor 5. (165 aa)
LOC459970Stress-70 protein, mitochondrial pseudogene. (640 aa)
EZH2Enhancer of zeste homolog 2. (754 aa)
LBHLBH regulator of WNT signaling pathway. (111 aa)
ENSPTRP00000069497annotation not available (53 aa)
CDK12Cyclin-dependent kinase 12. (1490 aa)
ZFP36L2Zinc finger protein 36, C3H type-like 2. (492 aa)
N4BP2L2N4BP2L2 isoform 1. (737 aa)
NFE2L2Nuclear factor (Erythroid-derived 2)-like 2. (605 aa)
ESRRBEstrogen related receptor beta. (508 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
TCF15Transcription factor 15. (197 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TMSB4XThymosin beta 4 X-linked. (44 aa)
NELFBNELFB isoform 1. (730 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
RESTRE1 silencing transcription factor. (1097 aa)
NOTCH1NOTCH1 isoform 1. (2555 aa)
CDK13Cyclin dependent kinase 13. (1512 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.