STRINGSTRING
USP22 USP22 ENSPTRP00000092677 ENSPTRP00000092677 ENSPTRP00000088036 ENSPTRP00000088036 ENY2 ENY2 SUPT3H SUPT3H ATXN7 ATXN7 TAF9 TAF9 LOC100610514 LOC100610514 SUPT20HL2 SUPT20HL2 TAF5L TAF5L SUPT20H SUPT20H ENSPTRP00000070717 ENSPTRP00000070717 USP51 USP51 ATXN7L3 ATXN7L3 TADA1 TADA1 TAF6L TAF6L TAF10 TAF10 TRRAP TRRAP SUPT7L SUPT7L SF3B5 SF3B5 TADA2B TADA2B TADA3 TADA3 TADA2A TADA2A SF3B3 SF3B3 SGF29 SGF29 TAF12 TAF12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa)
ENSPTRP00000092677annotation not available (711 aa)
ENSPTRP00000088036annotation not available (243 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (100 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (424 aa)
ATXN7ATXN7 isoform 2. (939 aa)
TAF9TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa)
LOC100610514Transcription factor SPT20 homolog-like 1. (821 aa)
SUPT20HL2Putative transcription factor SPT20 homolog-like 2. (786 aa)
TAF5LTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (589 aa)
SUPT20HSPT20 homolog, SAGA complex component. (811 aa)
ENSPTRP00000070717annotation not available (287 aa)
USP51Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (711 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
TADA1Transcriptional adaptor 1. (335 aa)
TAF6LTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa. (603 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (414 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
TADA2BTranscriptional adapter. (420 aa)
TADA3Transcriptional adaptor 3. (432 aa)
TADA2ATranscriptional adapter. (443 aa)
SF3B3Splicing factor 3b, subunit 3, 130kDa. (1217 aa)
SGF29SGF29 isoform 6. (265 aa)
TAF12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.