STRINGSTRING
L1CAM L1CAM YWHAB YWHAB PDIA3 PDIA3 ENAH ENAH ITGB5 ITGB5 ENSPTRP00000050767 ENSPTRP00000050767 RND3 RND3 XIRP2 XIRP2 ADGRE5 ADGRE5 RHOG RHOG FLNC FLNC PPP1R12A PPP1R12A NUMB NUMB ABCB4 ABCB4 LASP1 LASP1 TNS3 TNS3 TPM4 TPM4 ENG ENG GSN GSN PGM5 PGM5 FOCAD FOCAD PTK2B PTK2B SORBS3 SORBS3 DLC1 DLC1 ZYX ZYX TRIP6 TRIP6 ARPC1B ARPC1B YWHAG YWHAG HSPB1 HSPB1 RALA RALA MARCKS MARCKS HSPA9 HSPA9 ARL2 ARL2 ITGA1 ITGA1 ANXA5 ANXA5 ARHGAP24 ARHGAP24 SCARB2 SCARB2 AFAP1 AFAP1 ADD1 ADD1 LPP LPP RHOA RHOA LIMD1 LIMD1 CDC42EP1 CDC42EP1 MAPK1 MAPK1 TGM2 TGM2 HCK HCK UBOX5 UBOX5 FBLIM1 FBLIM1 EPHA2 EPHA2 HSPG2 HSPG2 JAK1 JAK1 CNN3 CNN3 DDR2 DDR2 DCAF6 DCAF6 ARPC5 ARPC5 PTPRC PTPRC CSRP1 CSRP1 ARF1 ARF1 RSU1 RSU1 SVIL SVIL NRP1 NRP1 ARHGAP22 ARHGAP22 CD151 CD151 RRAS2 RRAS2 ARL14EP ARL14EP CORO1B CORO1B REXO2 REXO2 MCAM MCAM CD9 CD9 SENP1 SENP1 LIMA1 LIMA1 ITGA5 ITGA5 AVIL AVIL CORO1C CORO1C LOC744940 LOC744940 ATP6V0A2 ATP6V0A2 FLT1 FLT1 LCP1 LCP1 EFNB2 EFNB2 MMP14 MMP14 EFS EFS EVL EVL ZFYVE21 ZFYVE21 SNAP23 SNAP23 TLN2 TLN2 CORO2B CORO2B PEAK1 PEAK1 FES FES CDH13 CDH13 YWHAE YWHAE PFN1 PFN1 ALOX15B ALOX15B FZD2 FZD2 ITGA3 ITGA3 MRC2 MRC2 PEAK3 PEAK3 PIP5K1C PIP5K1C MAP2K2 MAP2K2 CALR CALR PVR PVR RRAS RRAS YWHAQ YWHAQ LOC737606 LOC737606 FBLN7 FBLN7 ITGA4 ITGA4 TNS1 TNS1 NPM1-2 NPM1-2 GIT1 GIT1 LOC745166 LOC745166 ENSPTRP00000061448 ENSPTRP00000061448 CK820_G0021700 CK820_G0021700 ARHGEF7 ARHGEF7 TNS2 TNS2 IGF2R IGF2R MAP2K1 MAP2K1 FLNA FLNA ENSPTRP00000064369 ENSPTRP00000064369 ERAS ERAS PPFIA1 PPFIA1 ENSPTRP00000065064 ENSPTRP00000065064 STARD8 STARD8 LOC100615261 LOC100615261 ENSPTRP00000066329 ENSPTRP00000066329 MPRIP MPRIP LOC743115 LOC743115 RHOB RHOB FAT1 FAT1 PPFIBP1 PPFIBP1 LOC736481 LOC736481 LOC452254 LOC452254 ENSPTRP00000067007 ENSPTRP00000067007 SLC9A1 SLC9A1 CSPG4 CSPG4 ENSPTRP00000067251 ENSPTRP00000067251 CSRP2 CSRP2 ASAP3 ASAP3 CNN2 CNN2 ENSPTRP00000067778 ENSPTRP00000067778 ENSPTRP00000067815 ENSPTRP00000067815 CAPN1 CAPN1 SYNE2 SYNE2 NPM1 NPM1 ENSPTRP00000068383 ENSPTRP00000068383 PPP1CB PPP1CB RAC1 RAC1 ENSPTRP00000069037 ENSPTRP00000069037 RAC2 RAC2 PABPC1 PABPC1 ENSPTRP00000069368 ENSPTRP00000069368 ITGB1 ITGB1 LOC107970622 LOC107970622 FLRT2 FLRT2 ARHGEF2 ARHGEF2 ENSPTRP00000070303 ENSPTRP00000070303 ENSPTRP00000070691 ENSPTRP00000070691 ENSPTRP00000070693 ENSPTRP00000070693 LRP1 LRP1 PXN PXN ENSPTRP00000071463 ENSPTRP00000071463 GRB7 GRB7 ENSPTRP00000071544 ENSPTRP00000071544 DAB2 DAB2 TLN1 TLN1 ENSPTRP00000072166 ENSPTRP00000072166 FAM107A FAM107A RDX RDX ALCAM ALCAM DNM2 DNM2 NHS NHS LMLN2 LMLN2 PIP5K1A PIP5K1A CNN2-2 CNN2-2 ENSPTRP00000073936 ENSPTRP00000073936 ENSPTRP00000074059 ENSPTRP00000074059 YWHAZ YWHAZ ENSPTRP00000074371 ENSPTRP00000074371 TWF1 TWF1 ARPC3 ARPC3 PARVB PARVB LOC737257 LOC737257 ENSPTRP00000074910 ENSPTRP00000074910 CK820_G0026206 CK820_G0026206 PXN-2 PXN-2 ENSPTRP00000075125 ENSPTRP00000075125 ENSPTRP00000075289 ENSPTRP00000075289 GIT2 GIT2 ENSPTRP00000075494 ENSPTRP00000075494 ENSPTRP00000075745 ENSPTRP00000075745 S100A7 S100A7 ENSPTRP00000075918 ENSPTRP00000075918 CK820_G0040447 CK820_G0040447 ENSPTRP00000076371 ENSPTRP00000076371 LMLN LMLN ENSPTRP00000076466 ENSPTRP00000076466 SRC SRC ENSPTRP00000076865 ENSPTRP00000076865 ENSPTRP00000077199 ENSPTRP00000077199 CK820_G0051333 CK820_G0051333 HSP90B1 HSP90B1 CDC42 CDC42 LOC100611246 LOC100611246 ENSPTRP00000077947 ENSPTRP00000077947 IRF2 IRF2 ENSPTRP00000078387 ENSPTRP00000078387 ENSPTRP00000078893 ENSPTRP00000078893 PDLIM7 PDLIM7 LOC459970 LOC459970 BCAR1 BCAR1 MAP4K4 MAP4K4 LOC100615440 LOC100615440 LAYN LAYN SYNPO2 SYNPO2 ACTN2 ACTN2 MAPRE1 MAPRE1 ACTN4 ACTN4 MAPRE2 MAPRE2 FERMT2 FERMT2 PRUNE1 PRUNE1 ANXA6 ANXA6 ENSPTRP00000081537 ENSPTRP00000081537 ENSPTRP00000081955 ENSPTRP00000081955 RPLP0 RPLP0 JAK2 JAK2 CTTN CTTN ENSPTRP00000082446 ENSPTRP00000082446 ITGA2 ITGA2 AKAP12 AKAP12 BCAR3 BCAR3 ENSPTRP00000083520 ENSPTRP00000083520 CK820_G0012542 CK820_G0012542 PTK2 PTK2 ITGA11 ITGA11 ICAM1 ICAM1 RAC1-2 RAC1-2 KRAS KRAS PALLD PALLD GNB2 GNB2 LOC459638 LOC459638 LIMS2 LIMS2 ENSPTRP00000085517 ENSPTRP00000085517 ITGA8 ITGA8 ENSPTRP00000085830 ENSPTRP00000085830 ACTN3 ACTN3 FHL1 FHL1 ENSPTRP00000086247 ENSPTRP00000086247 FHL2 FHL2 ENSPTRP00000087196 ENSPTRP00000087196 MSN MSN SORBS1 SORBS1 ADGRE5-2 ADGRE5-2 FZD1 FZD1 ITGA6 ITGA6 PIPSL PIPSL LMO7 LMO7 FERMT1 FERMT1 ENSPTRP00000088520 ENSPTRP00000088520 ENSPTRP00000088582 ENSPTRP00000088582 ENSPTRP00000088766 ENSPTRP00000088766 CASS4 CASS4 FLNB FLNB NECTIN2 NECTIN2 CNN1 CNN1 PARVA PARVA ENSPTRP00000089993 ENSPTRP00000089993 ARPC2 ARPC2 PAK4 PAK4 TNS4 TNS4 PDPK1 PDPK1 MME MME ENSPTRP00000090501 ENSPTRP00000090501 ENSPTRP00000090508 ENSPTRP00000090508 YES1 YES1 RPLP0-2 RPLP0-2 ENSPTRP00000090995 ENSPTRP00000090995 CAPN2 CAPN2 VASP VASP ARL14EPL ARL14EPL ENSPTRP00000091405 ENSPTRP00000091405 ENSPTRP00000091594 ENSPTRP00000091594 PRAG1 PRAG1 LOC460237 LOC460237 ACTR2 ACTR2 ENSPTRP00000092145 ENSPTRP00000092145 LOC459477 LOC459477 ENSPTRP00000092498 ENSPTRP00000092498 GNB2-2 GNB2-2 ADAM9 ADAM9 FZD1-2 FZD1-2 NEDD9 NEDD9 EZR EZR PTPRA PTPRA CK820_G0015929 CK820_G0015929 PLAUR PLAUR NEXN NEXN MAPK3 MAPK3 THSD1 THSD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L1CAML1 cell adhesion molecule. (1257 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
ENAHENAH actin regulator. (790 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
ENSPTRP00000050767Ras suppressor protein 1-like. (111 aa)
RND3Rho family GTPase 3. (244 aa)
XIRP2XIRP2 isoform 3. (3549 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (840 aa)
RHOGRas homolog gene family, member G (Rho G). (191 aa)
FLNCFilamin C, gamma. (2725 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
NUMBNUMB endocytic adaptor protein. (651 aa)
ABCB4ABCB4 isoform 4. (1286 aa)
LASP1LIM and SH3 protein 1. (261 aa)
TNS3TNS3 isoform 2. (1445 aa)
TPM4TPM4 isoform 4; Belongs to the tropomyosin family. (239 aa)
ENGENG isoform 1. (658 aa)
GSNGSN isoform 3. (782 aa)
PGM5Uncharacterized protein; Belongs to the phosphohexose mutase family. (567 aa)
FOCADFOCAD isoform 1. (1801 aa)
PTK2BPTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
ZYXZYX isoform 1. (572 aa)
TRIP6Thyroid receptor-interacting protein 6. (476 aa)
ARPC1BActin related protein 2/3 complex, subunit 1A/1B. (372 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Belongs to the 14-3-3 family. (247 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
RALAV-ral simian leukemia viral oncogene homolog A (Ras related). (206 aa)
MARCKSMyristoylated alanine-rich protein kinase C substrate. (332 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
ARL2ARL2-SNX15 isoform 1; Belongs to the small GTPase superfamily. Arf family. (184 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
ANXA5Annexin A5; This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. (320 aa)
ARHGAP24Rho GTPase activating protein 24. (748 aa)
SCARB2Scavenger receptor class B, member 2; Belongs to the CD36 family. (478 aa)
AFAP1Actin filament associated protein 1. (814 aa)
ADD1ADD1 isoform 5. (768 aa)
LPPLIM domain containing preferred translocation partner in lipoma. (612 aa)
RHOARas homolog family member A. (193 aa)
LIMD1LIM domains containing 1. (676 aa)
CDC42EP1CDC42 effector protein (Rho GTPase binding) 1. (391 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
TGM2Transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase). (687 aa)
HCKTyrosine-protein kinase. (526 aa)
UBOX5U-box domain containing 5. (541 aa)
FBLIM1Filamin binding LIM protein 1. (374 aa)
EPHA2EPH receptor A2. (976 aa)
HSPG2HSPG2 isoform 1. (4390 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
DCAF6DDB1 and CUL4 associated factor 6. (951 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1306 aa)
CSRP1Cysteine and glycine-rich protein 1. (193 aa)
ARF1ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RSU1Ras suppressor protein 1. (277 aa)
SVILSVIL isoform 6. (2214 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ARHGAP22Beta 1,3-galactosyltransferase-like. (715 aa)
CD151Tetraspanin. (253 aa)
RRAS2Related RAS viral (R-ras) oncogene homolog 2. (204 aa)
ARL14EPADP ribosylation factor like GTPase 14 effector protein. (260 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
REXO2REX2, RNA exonuclease 2 homolog. (237 aa)
MCAMMelanoma cell adhesion molecule. (646 aa)
CD9Tetraspanin. (228 aa)
SENP1SUMO1/sentrin specific peptidase 1. (644 aa)
LIMA1LIM domain and actin binding 1. (735 aa)
ITGA5ITGA5 isoform 2; Belongs to the integrin alpha chain family. (1098 aa)
AVILAVIL isoform 2. (819 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
LOC74494060S acidic ribosomal protein P0-like. (315 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
EFSEmbryonal Fyn-associated substrate. (560 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
ZFYVE21Zinc finger, FYVE domain containing 21. (252 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
TLN2TLN2 isoform 1. (2544 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (480 aa)
PEAK1NKF3 kinase family member. (1746 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
CDH13CDH13 isoform 2. (760 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Belongs to the 14-3-3 family. (255 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
ALOX15BArachidonate 15-lipoxygenase, type B. (676 aa)
FZD2FZD2 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (548 aa)
ITGA3ITGA3 isoform 6; Belongs to the integrin alpha chain family. (1066 aa)
MRC2Mannose receptor, C type 2. (1479 aa)
PEAK3PEAK family member 3. (473 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
CALRCalreticulin. (414 aa)
PVRPVR cell adhesion molecule. (417 aa)
RRASRelated RAS viral (R-ras) oncogene homolog. (218 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Belongs to the 14-3-3 family. (253 aa)
LOC737606T0172536 isoform 1. (398 aa)
FBLN7FBLN7 isoform 1. (439 aa)
ITGA4Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor); Belongs to the integrin alpha chain family. (1032 aa)
TNS1TNS1 isoform 5. (1740 aa)
NPM1-2NPM1 isoform 5. (306 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
LOC745166HSPA1A isoform 1; Belongs to the heat shock protein 70 family. (643 aa)
ENSPTRP00000061448annotation not available (572 aa)
CK820_G0021700RPLP0 isoform 4. (308 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
TNS2TNS2 isoform 7. (1419 aa)
IGF2RIGF2R isoform 2. (2491 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa)
FLNAFLNA isoform 8. (2711 aa)
ENSPTRP00000064369annotation not available (492 aa)
ERASES cell expressed Ras. (233 aa)
PPFIA1PPFIA1 isoform 2. (1267 aa)
ENSPTRP00000065064annotation not available (405 aa)
STARD8StAR-related lipid transfer (START) domain containing 8. (1108 aa)
LOC10061526114-3-3 protein theta-like. (74 aa)
ENSPTRP00000066329annotation not available (241 aa)
MPRIPMyosin phosphatase Rho interacting protein. (1023 aa)
LOC743115Nucleophosmin pseudogene. (255 aa)
RHOBRas homolog gene family, member B. (286 aa)
FAT1FAT tumor suppressor homolog 1. (4600 aa)
PPFIBP1PPFIBP1 isoform 1. (1010 aa)
LOC736481Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa)
LOC452254LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 1-like. (863 aa)
ENSPTRP00000067007annotation not available (251 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2421 aa)
ENSPTRP00000067251annotation not available (74 aa)
CSRP2Cysteine and glycine rich protein 2. (243 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (905 aa)
CNN2CNN2 isoform 9. (148 aa)
ENSPTRP00000067778annotation not available (85 aa)
ENSPTRP00000067815annotation not available (246 aa)
CAPN1Calpain 1, (Mu/I) large subunit; Belongs to the peptidase C2 family. (733 aa)
SYNE2SYNE2 isoform 1. (6907 aa)
NPM1NPM1 isoform 1. (294 aa)
ENSPTRP00000068383annotation not available (114 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (331 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
ENSPTRP00000069037annotation not available (328 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). (207 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
ENSPTRP00000069368annotation not available (459 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LOC107970622MPRIP isoform 1. (1021 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
ENSPTRP00000070303annotation not available (117 aa)
ENSPTRP00000070691annotation not available (323 aa)
ENSPTRP00000070693annotation not available (228 aa)
LRP1LDL receptor related protein 1. (4544 aa)
PXNPXN isoform 20. (1078 aa)
ENSPTRP00000071463LOW QUALITY PROTEIN: chondroitin sulfate proteoglycan 4. (205 aa)
GRB7Growth factor receptor bound protein 7. (555 aa)
ENSPTRP00000071544annotation not available (1118 aa)
DAB2Disabled homolog 2, mitogen-responsive phosphoprotein. (770 aa)
TLN1TLN1 isoform 1. (2558 aa)
ENSPTRP00000072166annotation not available (318 aa)
FAM107AActin-associated protein FAM107A; Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F- actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal [...] (175 aa)
RDXRDX isoform 3. (609 aa)
ALCAMActivated leukocyte cell adhesion molecule. (590 aa)
DNM2DNM2 isoform 5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
NHSNHS actin remodeling regulator. (1630 aa)
LMLN2Leishmanolysin-like peptidase. (786 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
CNN2-2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (281 aa)
ENSPTRP00000073936annotation not available (283 aa)
ENSPTRP00000074059annotation not available (180 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Belongs to the 14-3-3 family. (245 aa)
ENSPTRP00000074371annotation not available (264 aa)
TWF1Twinfilin actin binding protein 1. (380 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
PARVBBeta-parvin isoform X1. (397 aa)
LOC737257Nucleophosmin pseudogene. (312 aa)
ENSPTRP00000074910annotation not available (405 aa)
CK820_G0026206TPM4 isoform 9. (233 aa)
PXN-2PXN isoform 9. (1081 aa)
ENSPTRP00000075125annotation not available (537 aa)
ENSPTRP00000075289annotation not available (193 aa)
GIT2G protein-coupled receptor kinase interacting ArfGAP 2. (760 aa)
ENSPTRP00000075494annotation not available (194 aa)
ENSPTRP00000075745annotation not available (296 aa)
S100A7Protein S100; Belongs to the S-100 family. (101 aa)
ENSPTRP00000075918annotation not available (365 aa)
CK820_G0040447CAPN2 isoform 2; Belongs to the peptidase C2 family. (708 aa)
ENSPTRP00000076371annotation not available (194 aa)
LMLNLeishmanolysin-like peptidase. (692 aa)
ENSPTRP00000076466annotation not available (163 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000076865annotation not available (107 aa)
ENSPTRP00000077199annotation not available (206 aa)
CK820_G0051333Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (200 aa)
HSP90B1Heat shock protein 90 beta family member 1. (814 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
LOC10061124614-3-3 protein zeta/delta pseudogene. (212 aa)
ENSPTRP00000077947annotation not available (48 aa)
IRF2Interferon regulatory factor. (349 aa)
ENSPTRP00000078387annotation not available (202 aa)
ENSPTRP00000078893annotation not available (168 aa)
PDLIM7PDZ and LIM domain 7 (Enigma). (459 aa)
LOC459970Stress-70 protein, mitochondrial pseudogene. (640 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
MAP4K4MAP4K4 isoform 6. (1347 aa)
LOC100615440Moesin pseudogene. (516 aa)
LAYNLAYN isoform 4. (382 aa)
SYNPO2SYNPO2 isoform 2. (1255 aa)
ACTN2ACTN2 isoform 2. (894 aa)
MAPRE1MAPRE1 isoform 1. (268 aa)
ACTN4Actinin, alpha 4. (931 aa)
MAPRE2Microtubule-associated protein, RP/EB family, member 2. (327 aa)
FERMT2Fermitin family member 2. (706 aa)
PRUNE1Prune exopolyphosphatase 1. (453 aa)
ANXA6Annexin. (788 aa)
ENSPTRP00000081537annotation not available (449 aa)
ENSPTRP00000081955annotation not available (66 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
CTTNCTTN isoform 2. (634 aa)
ENSPTRP00000082446annotation not available (194 aa)
ITGA2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Belongs to the integrin alpha chain family. (1183 aa)
AKAP12AKAP12 isoform 1. (1780 aa)
BCAR3Breast cancer anti-estrogen resistance 3. (825 aa)
ENSPTRP00000083520annotation not available (273 aa)
CK820_G0012542ACTR3 isoform 5. (34 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1206 aa)
ICAM1Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. (537 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
PALLDPalladin, cytoskeletal associated protein. (1123 aa)
GNB2Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
LOC45963814-3-3 protein epsilon-like. (255 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
ENSPTRP00000085517annotation not available (294 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ENSPTRP00000085830annotation not available (168 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
FHL1Four and a half LIM domains 1. (339 aa)
ENSPTRP00000086247annotation not available (513 aa)
FHL2FHL2 isoform 4. (389 aa)
ENSPTRP00000087196annotation not available (261 aa)
MSNMSN isoform 1. (577 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
ADGRE5-2Adhesion G protein-coupled receptor E5. (854 aa)
FZD1FZD1 isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
PIPSLPIP5K1A and PSMD4-like. (548 aa)
LMO7LMO7 isoform 2. (1668 aa)
FERMT1Fermitin family member 1. (677 aa)
ENSPTRP00000088520annotation not available (242 aa)
ENSPTRP00000088582annotation not available (66 aa)
ENSPTRP00000088766annotation not available (199 aa)
CASS4CASS4 isoform 2. (812 aa)
FLNBFilamin B, beta. (2633 aa)
NECTIN2Poliovirus receptor-related 2 (Herpesvirus entry mediator B). (542 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (299 aa)
PARVAPARVA isoform 1. (412 aa)
ENSPTRP00000089993annotation not available (58 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
TNS4TNS4 isoform 1. (715 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
MMEMembrane metallo-endopeptidase. (750 aa)
ENSPTRP00000090501annotation not available (192 aa)
ENSPTRP00000090508annotation not available (289 aa)
YES1Tyrosine-protein kinase. (558 aa)
RPLP0-2Ribosomal protein lateral stalk subunit P0. (317 aa)
ENSPTRP00000090995annotation not available (206 aa)
CAPN2Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. (703 aa)
VASPVasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
ARL14EPLADP ribosylation factor like GTPase 14 effector protein like. (152 aa)
ENSPTRP00000091405annotation not available (334 aa)
ENSPTRP00000091594annotation not available (255 aa)
PRAG1PRAG1 isoform 1. (1408 aa)
LOC460237TPM4 isoform 1; Belongs to the tropomyosin family. (241 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSPTRP00000092145annotation not available (318 aa)
LOC459477T0188211 isoform 1. (343 aa)
ENSPTRP00000092498Supervillin-like. (133 aa)
GNB2-2G protein subunit beta 2. (372 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
FZD1-2Frizzled class receptor 1. (580 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
EZREZR isoform 1. (671 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
CK820_G0015929ARPC3 isoform 3. (178 aa)
PLAURUrokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form (By similarity). (335 aa)
NEXNNexilin (F actin binding protein). (675 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
THSD1Thrombospondin, type I, domain containing 1. (853 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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