STRINGSTRING
SKI SKI KLHL20 KLHL20 TRIM8 TRIM8 ZBTB16 ZBTB16 NFE2 NFE2 PML PML BLM BLM CIITA CIITA N4BP1 N4BP1 TP53 TP53 CHD3 CHD3 TRIM16-2 TRIM16-2 MAPK7 MAPK7 RDM1 RDM1 MKNK2 MKNK2 PIAS4 PIAS4 SP140L SP140L SP100 SP100 TP53INP2 TP53INP2 MORC3 MORC3 TOPBP1 TOPBP1 TENM2 TENM2 TDP2 TDP2 DAXX DAXX LRCH4 LRCH4 HIPK2 HIPK2 TP53INP1 TP53INP1 CDK9 CDK9 GCNA GCNA TEX13B TEX13B ZCCHC12 ZCCHC12 TOP3A TOP3A ATR ATR ZMYM2 ZMYM2 ENSPTRP00000060015 ENSPTRP00000060015 ISG20 ISG20 TRIM16 TRIM16 ANKRD2 ANKRD2 ZBED1 ZBED1 LOC107966301-2 LOC107966301-2 ENSPTRP00000066621 ENSPTRP00000066621 CHEK2 CHEK2 BASP1 BASP1 RAD51 RAD51 LOC107971228 LOC107971228 SKIL SKIL ENSPTRP00000070902 ENSPTRP00000070902 SATB1 SATB1 LOC107966301 LOC107966301 IKBKE IKBKE LRCH4-2 LRCH4-2 USP7 USP7 CK820_G0002104 CK820_G0002104 PARK7 PARK7 EIF3E EIF3E SUMO3 SUMO3 PIAS1 PIAS1 ELF4 ELF4 ZCCHC18 ZCCHC18 ENSPTRP00000082006 ENSPTRP00000082006 ENSPTRP00000083257 ENSPTRP00000083257 SUMO1-2 SUMO1-2 UBN1 UBN1 ENSPTRP00000085085 ENSPTRP00000085085 SP3 SP3 SP100-2 SP100-2 SUMO1-3 SUMO1-3 ENSPTRP00000085903 ENSPTRP00000085903 CHFR CHFR SUMO3-2 SUMO3-2 CALCOCO2 CALCOCO2 HSF1 HSF1 MLIP MLIP RNF4 RNF4 SUMO1 SUMO1 RPAIN RPAIN ENSPTRP00000090440 ENSPTRP00000090440 ENSPTRP00000091865 ENSPTRP00000091865 SP140 SP140 ENSPTRP00000093022 ENSPTRP00000093022 CASP8AP2 CASP8AP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKIV-ski sarcoma viral oncogene homolog (Avian). (736 aa)
KLHL20Kelch like family member 20. (609 aa)
TRIM8Tripartite motif containing 8. (551 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
PMLPML isoform 6. (836 aa)
BLMBLM isoform 1. (1417 aa)
CIITAClass II major histocompatibility complex transactivator. (1131 aa)
N4BP1NEDD4 binding protein 1. (896 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2058 aa)
TRIM16-2Tripartite motif containing 16. (560 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
RDM1RAD52 motif containing 1. (284 aa)
MKNK2MAP kinase interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
PIAS4Protein inhibitor of activated STAT protein 4. (510 aa)
SP140LSP140 nuclear body protein like. (580 aa)
SP100Nuclear autoantigen Sp-100. (885 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
TOPBP1Topoisomerase (DNA) II binding protein 1. (1522 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (362 aa)
DAXXDeath domain associated protein. (742 aa)
LRCH4Leucine-rich repeats and calponin homology (CH) domain containing 4. (683 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
TP53INP1TP53INP1 isoform 1. (240 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
GCNAGCNA isoform 1. (584 aa)
TEX13BTestis expressed 13B. (312 aa)
ZCCHC12Zinc finger CCHC-type containing 12. (402 aa)
TOP3ADNA topoisomerase III alpha. (1001 aa)
ATRAtaxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. (2644 aa)
ZMYM2Zinc finger MYM-type containing 2. (1377 aa)
ENSPTRP00000060015annotation not available (190 aa)
ISG20Interferon stimulated exonuclease gene 20kDa. (181 aa)
TRIM16T0195358 isoform 1. (564 aa)
ANKRD2Ankyrin repeat domain 2. (360 aa)
ZBED1Zinc finger, BED-type containing 1. (694 aa)
LOC107966301-2MAGEA2 isoform 1. (314 aa)
ENSPTRP00000066621annotation not available (709 aa)
CHEK2Checkpoint kinase 2. (586 aa)
BASP1Brain abundant, membrane attached signal protein 1. (226 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
LOC107971228Melanoma-associated antigen 2. (314 aa)
SKILSKI like proto-oncogene. (684 aa)
ENSPTRP00000070902annotation not available (168 aa)
SATB1DNA-binding protein SATB. (795 aa)
LOC107966301Melanoma-associated antigen 2. (314 aa)
IKBKEInhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon. (716 aa)
LRCH4-2Leucine rich repeats and calponin homology domain containing 4. (683 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1121 aa)
CK820_G0002104EIF3E isoform 7; Belongs to the eIF-3 subunit E family. (183 aa)
PARK7PARK7 isoform 1. (189 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (496 aa)
SUMO3SUMO3 isoform 5. (140 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
ELF4E74-like factor 4 (Ets domain transcription factor). (663 aa)
ZCCHC18ZCCHC18 isoform 2. (377 aa)
ENSPTRP00000082006annotation not available (312 aa)
ENSPTRP00000083257annotation not available (412 aa)
SUMO1-2Small ubiquitin-related modifier. (82 aa)
UBN1UBN1 isoform 1. (1160 aa)
ENSPTRP00000085085annotation not available (84 aa)
SP3Sp3 transcription factor. (781 aa)
SP100-2Nuclear autoantigen Sp-100; Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regul [...] (187 aa)
SUMO1-3Small ubiquitin-related modifier. (98 aa)
ENSPTRP00000085903annotation not available (98 aa)
CHFRCheckpoint with forkhead and ring finger domains. (664 aa)
SUMO3-2Small ubiquitin-related modifier. (103 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (467 aa)
HSF1Heat shock transcription factor 1. (529 aa)
MLIPMuscular LMNA interacting protein. (993 aa)
RNF4Ring finger protein 4. (190 aa)
SUMO1SUMO1 isoform 3. (146 aa)
RPAINRPA interacting protein. (231 aa)
ENSPTRP00000090440annotation not available (72 aa)
ENSPTRP00000091865annotation not available (183 aa)
SP140SP140 nuclear body protein. (866 aa)
ENSPTRP00000093022annotation not available (563 aa)
CASP8AP2CASP8AP2 isoform 4. (2049 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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