(51 nodes) SCF ubiquitin ligase complex network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXO2	F-box protein 2. (295 aa)
	DCUN1D3	DCN1-like protein. (304 aa)
	ENSPTRP00000091457	annotation not available (64 aa)
	FBXL14	F-box and leucine-rich repeat protein 14. (418 aa)
	FBXO17	F-box only protein 17 isoform X1. (278 aa)
	CUL1-2	Cullin 1. (776 aa)
	FBXL17	F-box and leucine rich repeat protein 17. (715 aa)
	ENSPTRP00000080848	annotation not available (88 aa)
	FBXL22	F-box and leucine rich repeat protein 22. (247 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (472 aa)
	ENSPTRP00000078561	annotation not available (79 aa)
	FBXL21P	F-box and leucine-rich repeat protein 21. (432 aa)
	FBXW11	F-box and WD repeat domain containing 11. (563 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (694 aa)
	ENSPTRP00000075658	annotation not available (79 aa)
	ENSPTRP00000071907	annotation not available (164 aa)
	SKP1	T0093123 isoform 1; Belongs to the SKP1 family. (163 aa)
	FBXL15	F-box and leucine-rich repeat protein 15. (300 aa)
	ENSPTRP00000064916	annotation not available (631 aa)
	FBXO32	F-box protein 32. (355 aa)
	FBXO41	F-box protein 41. (879 aa)
	ENSPTRP00000063576	annotation not available (285 aa)
	CCNF	CCNF isoform 1; Belongs to the cyclin family. (786 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
	FBXO44	F-box protein 44. (255 aa)
	FLI1	Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
	FBXL3	F-box and leucine-rich repeat protein 3. (428 aa)
	FBXO31	F-box protein 31. (543 aa)
	FBXW5	F-box and WD repeat domain containing 5. (566 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXO25	F-box protein 25. (367 aa)
	CUL1	CUL1 isoform 1; Belongs to the cullin family. (776 aa)
	ZC3HC1	ZC3HC1 isoform 1. (502 aa)
	FBXO9	F-box protein 9. (437 aa)
	FBXO38	F-box protein 38. (1188 aa)
	FBXO4	F-box protein 4. (387 aa)
	SKP2	S-phase kinase-associated protein 2 (P45). (425 aa)
	FBXL7	F-box and leucine-rich repeat protein 7. (491 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	FBXL5	F-box and leucine-rich repeat protein 5. (691 aa)
	FBXO45	F-box protein 45. (286 aa)
	RBX1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	FBXO27	F-box protein 27. (283 aa)
	FBXL12	F-box and leucine-rich repeat protein 12. (326 aa)
	LRRC29	Leucine-rich repeat-containing protein 29. (214 aa)
	FBXO33	F-box protein 33. (557 aa)
	FBH1	FBXO18 isoform 3. (1096 aa)
	TMEM183A	Transmembrane protein 183A. (376 aa)
	FBXO42	F-box protein 42. (717 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CCNF	ENSPTRP00000077054	ENSPTRP00000059162	Beta-transducin repeat containing E3 ubiquitin protein ligase.	CCNF isoform 1; Belongs to the cyclin family.	0.699
BTRC	CUL1	ENSPTRP00000077054	ENSPTRP00000033967	Beta-transducin repeat containing E3 ubiquitin protein ligase.	CUL1 isoform 1; Belongs to the cullin family.	0.996
BTRC	CUL1-2	ENSPTRP00000077054	ENSPTRP00000086353	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1.	0.970
BTRC	ENSPTRP00000064916	ENSPTRP00000077054	ENSPTRP00000064916	Beta-transducin repeat containing E3 ubiquitin protein ligase.	annotation not available	0.970
BTRC	ENSPTRP00000071907	ENSPTRP00000077054	ENSPTRP00000071907	Beta-transducin repeat containing E3 ubiquitin protein ligase.	annotation not available	0.980
BTRC	FBXL14	ENSPTRP00000077054	ENSPTRP00000089686	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine-rich repeat protein 14.	0.467
BTRC	FBXL3	ENSPTRP00000077054	ENSPTRP00000043543	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine-rich repeat protein 3.	0.572
BTRC	FBXL5	ENSPTRP00000077054	ENSPTRP00000027433	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine-rich repeat protein 5.	0.472
BTRC	FBXL7	ENSPTRP00000077054	ENSPTRP00000028725	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine-rich repeat protein 7.	0.410
BTRC	FBXO2	ENSPTRP00000077054	ENSPTRP00000000286	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.964
BTRC	FBXO4	ENSPTRP00000077054	ENSPTRP00000028852	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.933
BTRC	FBXW11	ENSPTRP00000077054	ENSPTRP00000078073	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.907
BTRC	FBXW7	ENSPTRP00000077054	ENSPTRP00000028353	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.965
BTRC	RBX1	ENSPTRP00000077054	ENSPTRP00000024839	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ring-box 1, E3 ubiquitin protein ligase.	0.999
BTRC	SKP1	ENSPTRP00000077054	ENSPTRP00000069790	Beta-transducin repeat containing E3 ubiquitin protein ligase.	T0093123 isoform 1; Belongs to the SKP1 family.	0.999
BTRC	SKP2	ENSPTRP00000077054	ENSPTRP00000028804	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase-associated protein 2 (P45).	0.977
BTRC	USP47	ENSPTRP00000077054	ENSPTRP00000058577	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.	0.777
CCNF	BTRC	ENSPTRP00000059162	ENSPTRP00000077054	CCNF isoform 1; Belongs to the cyclin family.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.699
CCNF	CKS1B	ENSPTRP00000059162	ENSPTRP00000002352	CCNF isoform 1; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.630
CCNF	CKS2	ENSPTRP00000059162	ENSPTRP00000036054	CCNF isoform 1; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.561