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| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | FLOT1 | Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (427 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa) |
| | OLR1 | Oxidized low density lipoprotein (Lectin-like) receptor 1. (273 aa) |
| | ADTRP | Androgen dependent TFPI regulating protein. (248 aa) |
| | ENSPTRP00000029492 | annotation not available (223 aa) |
| | PLPP1 | Phospholipid phosphatase 1. (285 aa) |
| | TLR2 | Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (784 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2. (655 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | PLSCR2 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (297 aa) |
| | LRRK2 | Leucine-rich repeat kinase 2. (2527 aa) |
| | FAIM2 | FAIM2 isoform 2; Belongs to the BI1 family. (316 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (527 aa) |
| | ORAI1 | ORAI1 isoform 1. (301 aa) |
| | CLN6 | CLN6 isoform 13. (196 aa) |
| | ARID3A | ARID3A isoform 1. (590 aa) |
| | FURIN | Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family. (794 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | CDH1 | CDH1 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) |
| | CDH13 | CDH13 isoform 2. (760 aa) |
| | RANGRF | RAN guanine nucleotide release factor. (186 aa) |
| | SLC6A4 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (359 aa) |
| | CD226 | CD226 isoform 1. (336 aa) |
| | PLPP2 | PLPP2 isoform 5. (309 aa) |
| | PRKACA | PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa) |
| | PLVAP | Plasmalemma vesicle associated protein. (442 aa) |
| | FXYD1 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (81 aa) |
| | CLIP3 | CAP-Gly domain containing linker protein 3. (547 aa) |
| | EHD2-2 | EH-domain-containing protein 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa) |
| | TFPI | Tissue factor pathway inhibitor. (304 aa) |
| | CAVIN2 | Caveolae associated protein 2. (425 aa) |
| | RFTN2 | Raftlin family member 2. (501 aa) |
| | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | HCK | Tyrosine-protein kinase. (526 aa) |
| | CK820_G0037244 | NTSR1 isoform 1; Belongs to the G-protein coupled receptor 1 family. (350 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | RFTN1 | Raftlin, lipid raft linker 1. (578 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (188 aa) |
| | BVES | Blood vessel epicardial substance. (360 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa) |
| | LAT2 | Linker for activation of T cells family member 2. (243 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) |
| | DLC1 | DLC1 Rho GTPase activating protein. (1528 aa) |
| | ERLIN2 | ER lipid raft associated 2. (367 aa) |
| | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa) |
| | CAVIN4 | Muscle-related coiled-coil protein. (364 aa) |
| | ACE2 | Angiotensin-converting enzyme. (805 aa) |
| | HDAC6 | Histone deacetylase 6. (146 aa) |
| | BTK | BTK isoform 2. (693 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | LOC451223 | MS4A1 isoform 1. (297 aa) |
| | LOC742388 | CD177 isoform 1. (309 aa) |
| | ARID3C | AT-rich interaction domain 3C. (412 aa) |
| | MLC1 | MLC1 isoform 2. (347 aa) |
| | PLSCR1 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa) |
| | ADAM17 | ADAM17 isoform 3. (999 aa) |
| | ARC | Activity-regulated cytoskeleton-associated protein. (396 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) |
| | CD55 | CD55 isoform 7. (551 aa) |
| | SELPLG | SELPLG isoform 2. (428 aa) |
| | CAVIN1 | Caveolae associated protein 1. (390 aa) |
| | LAMTOR4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (137 aa) |
| | CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa) |
| | LOC471721 | Voltage-dependent anion channel 2. (297 aa) |
| | KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa) |
| | S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1286 aa) |
| | RTN4RL2 | Reticulon 4 receptor like 2. (420 aa) |
| | ENSPTRP00000062183 | annotation not available (243 aa) |
| | ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1. (2264 aa) |
| | CBL | Cas-Br-M (Murine) ecotropic retroviral transforming sequence. (906 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | SERPINH1 | Serpin peptidase inhibitor, clade H (Heat shock protein 47), member 1, (Collagen binding protein 1); Belongs to the serpin family. (418 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | MS4A15 | MS4A15 isoform 4. (240 aa) |
| | TPP1 | Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). (563 aa) |
| | HOGA1 | Phosphatidylinositol 4-kinase type 2 alpha. (479 aa) |
| | MYOF | MYOF isoform 3. (2061 aa) |
| | NPHS2 | NPHS2 stomatin family member, podocin. (383 aa) |
| | ITLN1 | ITLN1 isoform 1. (313 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (173 aa) |
| | LRP8 | LDL receptor related protein 8. (960 aa) |
| | LCK | Tyrosine-protein kinase. (539 aa) |
| | TNFRSF1B | Tumor necrosis factor receptor superfamily, member 1B. (461 aa) |
| | LOC737549 | Battenin. (418 aa) |
| | LOC104003639 | Guanine nucleotide-binding protein G(s) subunit alpha. (245 aa) |
| | SELE | SELE isoform 1. (612 aa) |
| | SLC38A9 | Solute carrier family 38, member 9. (561 aa) |
| | PPP2CA | PPP2CB isoform 8. (309 aa) |
| | SDCBP | Syndecan binding protein. (324 aa) |
| | ENSPTRP00000064832 | annotation not available (85 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily, member 1A. (455 aa) |
| | MAL2 | Mal, T cell differentiation protein 2. (176 aa) |
| | SLC1A2 | Amino acid transporter. (574 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa) |
| | CD8A | CD8A isoform 1. (235 aa) |
| | TNFRSF10A | Tumor necrosis factor receptor superfamily, member 10a. (469 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | CK820_G0010776 | TRPM8 isoform 5. (1112 aa) |
| | CK820_G0030851 | MS4A4E isoform 1. (154 aa) |
| | LOC739666 | Syntenin-1-like. (289 aa) |
| | ENSPTRP00000072507 | annotation not available (659 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (901 aa) |
| | GPM6B | Glycoprotein M6B. (305 aa) |
| | CD36 | CD36 molecule (Thrombospondin receptor); Belongs to the CD36 family. (472 aa) |
| | CD48 | CD48 isoform 2. (252 aa) |
| | TRPM8 | TRPM8 isoform 2. (1104 aa) |
| | CAVIN3 | Caveolae associated protein 3. (293 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa) |
| | EHD2 | EH domain containing 2. (543 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | ENSPTRP00000075929 | annotation not available (130 aa) |
| | RIT2 | Ras like without CAAX 2. (217 aa) |
| | CK820_G0040447 | CAPN2 isoform 2; Belongs to the peptidase C2 family. (708 aa) |
| | CD177 | CD177 isoform 3. (144 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | ENSPTRP00000076822 | annotation not available (142 aa) |
| | CTSD | T0155181 isoform 2; Belongs to the peptidase A1 family. (619 aa) |
| | ENSPTRP00000077063 | annotation not available (68 aa) |
| | STIM1 | Stromal interaction molecule 1. (791 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PLPP3 | T0036865 isoform 1. (342 aa) |
| | LAMTOR2-2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | SCARB1 | SCARB1 isoform 8; Belongs to the CD36 family. (552 aa) |
| | GP6 | GP6 isoform 1. (593 aa) |
| | GPC1 | GPC1 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa) |
| | LRP4 | Low density lipoprotein receptor-related protein 4. (1906 aa) |
| | CK820_G0057017 | CLN3 isoform 55. (42 aa) |
| | VDAC2 | VDAC2 isoform 1. (260 aa) |
| | STOM | STOM isoform 3. (288 aa) |
| | CBLC | Cbl proto-oncogene C. (474 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | CARD11 | Caspase recruitment domain family, member 11. (1154 aa) |
| | ENSPTRP00000086563 | annotation not available (245 aa) |
| | ENSPTRP00000087266 | Phosphoglycerate kinase 1. (394 aa) |
| | LOC455744 | LOW QUALITY PROTEIN: phosphoglycerate kinase 1-like. (408 aa) |
| | STOML2 | Stomatin (EPB72)-like 2. (361 aa) |
| | PTCH1 | PTCH1 isoform 8. (1428 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1294 aa) |
| | ENSPTRP00000088702 | annotation not available (170 aa) |
| | ENSPTRP00000089475 | annotation not available (268 aa) |
| | MYO1C | MYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa) |
| | MME | Membrane metallo-endopeptidase. (750 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and the formation of lipid rafts bearing GPI-anchor proteins. Regulates surface expression of MHC1 and ICAM1 proteins increasing susceptibility to T- cell mediated cytotoxicity. R [...] (167 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | CAPN2 | Calpain 2, (M/II) large subunit; Belongs to the peptidase C2 family. (703 aa) |
| | ITGB2 | Integrin beta. (863 aa) |
| | MYADM | Myeloid-associated differentiation marker. (322 aa) |
| | ANGPT1 | ANGPT1 isoform 2. (498 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (335 aa) |
| | EZR | EZR isoform 1. (671 aa) |
