STRINGSTRING
AQP1 AQP1 TRPC4 TRPC4 ANK1 ANK1 TFRC TFRC MLC1 MLC1 ENPP1 ENPP1 CD300LG CD300LG RHBG RHBG C5AR1 C5AR1 RHCG RHCG PHLDB2 PHLDB2 SLC47A1 SLC47A1 SLC26A7 SLC26A7 SLC39A8 SLC39A8 PHLDB1 PHLDB1 ATP2B1 ATP2B1 EPB41 EPB41 CLDN1 CLDN1 TF TF SLC26A6 SLC26A6 SLC16A8 SLC16A8 CLDN8 CLDN8 ANKRD60 ANKRD60 SLC13A3 SLC13A3 SPEF1 SPEF1 SLC4A11 SLC4A11 RAB17 RAB17 SLC40A1 SLC40A1 CA11 CA11 PHLDB3 PHLDB3 AQP4 AQP4 SLC16A3 SLC16A3 LPO LPO CA10 CA10 SLC4A1 SLC4A1 SLC51B SLC51B TJP1 TJP1 SLC10A1 SLC10A1 ABCC4 ABCC4 SLC7A1 SLC7A1 ERBB3 ERBB3 PIANP PIANP SLC22A9 SLC22A9 SLC22A24 SLC22A24 SLC22A25 SLC22A25 SLC43A3 SLC43A3 CNNM2 CNNM2 ANK3 ANK3 CD34 CD34 SLC41A1 SLC41A1 DSTYK DSTYK SLC16A1 SLC16A1 CLCA2 CLCA2 BSND BSND CLDN19 CLDN19 KCNQ4 KCNQ4 RAB42 RAB42 LDLRAP1 LDLRAP1 SLC29A2 SLC29A2 PDZD11 PDZD11 S100G-2 S100G-2 AQP3 AQP3 B4GALT1 B4GALT1 MFSD3 MFSD3 NOD1 NOD1 SLC16A10 SLC16A10 SLC12A2 SLC12A2 MARVELD2 MARVELD2 SLC51A SLC51A SLC22A8 SLC22A8 SLC22A6 SLC22A6 LOC737297 LOC737297 C5AR2 C5AR2 ERBB4 ERBB4 ERBIN ERBIN LOC749156 LOC749156 SLC4A4 SLC4A4 SLC26A10 SLC26A10 HEPH HEPH SLC39A14 SLC39A14 ATP7A ATP7A CK820_G0056924 CK820_G0056924 CLASP2 CLASP2 OSCP1 OSCP1 ENSPTRP00000065470 ENSPTRP00000065470 VSIG1 VSIG1 SLCO1C1 SLCO1C1 DLG1 DLG1 SLC38A3 SLC38A3 SLC22A7 SLC22A7 FRMPD2 FRMPD2 BEST1 BEST1 NKD2 NKD2 SLC46A1 SLC46A1 TEK TEK LRP1 LRP1 SLC29A1 SLC29A1 CLASP1 CLASP1 MUC20 MUC20 SLC23A2 SLC23A2 ENSPTRP00000072722 ENSPTRP00000072722 KCNJ4 KCNJ4 SLC4A7 SLC4A7 ABCC1 ABCC1 ENSPTRP00000075660 ENSPTRP00000075660 ENSPTRP00000075827 ENSPTRP00000075827 CADM1 CADM1 LOC742522 LOC742522 UMOD UMOD ABCC10 ABCC10 TGFA TGFA CK820_G0045857 CK820_G0045857 PLPP3 PLPP3 SLC12A6 SLC12A6 HFE HFE ABCC5 ABCC5 CK820_G0029270 CK820_G0029270 SLC6A6 SLC6A6 CK820_G0054983 CK820_G0054983 SLC41A1-2 SLC41A1-2 CK820_G0054628 CK820_G0054628 CDH17 CDH17 SLC19A1 SLC19A1 MAP7 MAP7 S100G S100G KCNQ1 KCNQ1 MYO1C MYO1C TSHR TSHR SLC7A8 SLC7A8 SLC14A1 SLC14A1 MYO1D MYO1D SLC22A10 SLC22A10 EZR EZR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQP1Aquaporin-1 isoform X2. (269 aa)
TRPC4Transient receptor potential cation channel, subfamily C, member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
ANK1ANK1 isoform 1. (1897 aa)
TFRCTransferrin receptor (P90, CD71). (760 aa)
MLC1MLC1 isoform 2. (347 aa)
ENPP1ENPP1 isoform 1. (925 aa)
CD300LGCD300 molecule like family member g. (332 aa)
RHBGAmmonium transporter Rh type B; Functions as a specific ammonium transporter; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (458 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. (351 aa)
RHCGAmmonium transporter Rh type C; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion (By similarity); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (479 aa)
PHLDB2Pleckstrin homology-like domain family B member 2 isoform X4. (1253 aa)
SLC47A1Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (586 aa)
SLC26A7Anion exchange transporter. (663 aa)
SLC39A8Solute carrier family 39 (Zinc transporter), member 8. (460 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1377 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
EPB41Erythrocyte membrane protein band 4.1. (864 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
TFSerotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation (By similarity). (698 aa)
SLC26A6Solute carrier family 26, member 6. (761 aa)
SLC16A8Solute carrier family 16 member 8. (504 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
ANKRD60Ankyrin repeat domain 60. (348 aa)
SLC13A3Solute carrier family 13 member 3. (602 aa)
SPEF1Sperm flagellar 1. (236 aa)
SLC4A11Solute carrier family 4 member 11. (918 aa)
RAB17RAB17, member RAS oncogene family. (211 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (571 aa)
CA11Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family. (328 aa)
PHLDB3PHLDB3 isoform 1. (641 aa)
AQP4AQP4 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
SLC16A3Solute carrier family 16, member 3 (Monocarboxylic acid transporter 4). (463 aa)
LPOLPO isoform 1. (712 aa)
CA10Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family. (328 aa)
SLC4A1Anion exchange protein. (921 aa)
SLC51BSolute carrier family 51 beta subunit. (128 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1748 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4. (1325 aa)
SLC7A1Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1. (629 aa)
ERBB3V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian). (1353 aa)
PIANPPILR alpha associated neural protein. (282 aa)
SLC22A9Solute carrier family 22 member 9. (553 aa)
SLC22A24Solute carrier family 22 member 24. (551 aa)
SLC22A25SLC22A25 isoform 1. (546 aa)
SLC43A3MFS transporter, LAT3 family, solute carrier family 43, member 3. (504 aa)
CNNM2Cyclin and CBS domain divalent metal cation transport mediator 2. (875 aa)
ANK3ANK3 isoform 5. (4377 aa)
CD34CD34 isoform 1. (328 aa)
SLC41A1Solute carrier family 41, member 1. (513 aa)
DSTYKDual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. (930 aa)
SLC16A1Solute carrier family 16, member 1 (Monocarboxylic acid transporter 1). (500 aa)
CLCA2CLCA2 isoform 1. (943 aa)
BSNDBSND isoform 1. (320 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
RAB42RAB42, member RAS oncogene family. (218 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
SLC29A2Solute carrier family 29 (Nucleoside transporters), member 2. (456 aa)
PDZD11PDZ domain containing 11. (140 aa)
S100G-2Protein S100; Belongs to the S-100 family. (79 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
B4GALT1UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1. (398 aa)
MFSD3MFSD3 isoform 1. (412 aa)
NOD1Nucleotide-binding oligomerization domain containing 1. (953 aa)
SLC16A10SLC16A10 isoform 2. (515 aa)
SLC12A2SLC12A2 isoform 1. (1211 aa)
MARVELD2MARVELD2 isoform 3. (559 aa)
SLC51ASolute carrier family 51 alpha subunit. (340 aa)
SLC22A8Solute carrier family 22 member 8. (542 aa)
SLC22A6Solute carrier family 22 member 6. (550 aa)
LOC737297Ras-related protein Rab-42-like. (218 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
ERBINErbb2 interacting protein. (1419 aa)
LOC749156Multidrug resistance-associated protein 6-like. (99 aa)
SLC4A4Anion exchange protein. (1100 aa)
SLC26A10SLC26A10 isoform 6. (553 aa)
HEPHHEPH isoform 1; Belongs to the multicopper oxidase family. (1212 aa)
SLC39A14SLC39A14 isoform 1. (490 aa)
ATP7AATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
CK820_G0056924NPIPA2 isoform 1. (277 aa)
CLASP2CLASP2 isoform 3. (1522 aa)
OSCP1OSCP1 isoform 4. (377 aa)
ENSPTRP00000065470annotation not available (146 aa)
VSIG1V-set and immunoglobulin domain containing 1. (423 aa)
SLCO1C1Solute carrier organic anion transporter family member. (730 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
SLC38A3Solute carrier family 38, member 3. (504 aa)
SLC22A7Solute carrier family 22 member 7. (548 aa)
FRMPD2FERM and PDZ domain containing 2. (1420 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (464 aa)
SLC46A1Solute carrier family 46 (Folate transporter), member 1. (459 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
LRP1LDL receptor related protein 1. (4544 aa)
SLC29A1Solute carrier family 29 (Nucleoside transporters), member 1. (523 aa)
CLASP1Cytoplasmic linker associated protein 1. (1549 aa)
MUC20Mucin 20, cell surface associated. (453 aa)
SLC23A2Solute carrier family 23 (Nucleobase transporters), member 2. (650 aa)
ENSPTRP00000072722annotation not available (129 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
SLC4A7Anion exchange protein. (1259 aa)
ABCC1ATP binding cassette subfamily C member 1. (1530 aa)
ENSPTRP00000075660annotation not available (165 aa)
ENSPTRP00000075827annotation not available (533 aa)
CADM1Cell adhesion molecule 1. (470 aa)
LOC742522ABCC6 isoform 1. (1503 aa)
UMODUMOD isoform 1. (690 aa)
ABCC10ATP-binding cassette, sub-family C (CFTR/MRP), member 10. (1496 aa)
TGFATGFA isoform 6. (193 aa)
CK820_G0045857MUC20 isoform 8. (431 aa)
PLPP3T0036865 isoform 1. (342 aa)
SLC12A6Solute carrier family 12 (Potassium/chloride transporters), member 6. (1151 aa)
HFEHereditary hemochromatosis protein homolog; Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. (348 aa)
ABCC5ATP-binding cassette, sub-family C (CFTR/MRP), member 5. (1437 aa)
CK820_G0029270IQANK1 isoform 1. (91 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (721 aa)
CK820_G0054983ABCC6 isoform 3. (435 aa)
SLC41A1-2Solute carrier family 41 member 1. (513 aa)
CK820_G0054628PKD1 isoform 4. (3384 aa)
CDH17CDH17 isoform 1. (867 aa)
SLC19A1Solute carrier family 19 member 1. (590 aa)
MAP7MAP7 isoform 7. (777 aa)
S100GS100 calcium binding protein G. (79 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
MYO1CMYO1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
SLC7A8Solute carrier family 7 (Amino acid transporter, L-type), member 8. (535 aa)
SLC14A1Urea transporter; Belongs to the urea transporter family. (445 aa)
MYO1DMYO1D isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
SLC22A10SLC22A10 isoform 4. (540 aa)
EZREZR isoform 1. (671 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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