STRINGSTRING
ARHGAP4 ARHGAP4 MCF2L MCF2L DLG2 DLG2 ARHGEF26 ARHGEF26 ABL2 ABL2 NEDD9 NEDD9 FCHSD2 FCHSD2 MYO15B MYO15B ITSN1-2 ITSN1-2 SH3GLB1 SH3GLB1 ARHGEF9 ARHGEF9 DST DST TNK2 TNK2 STAC2 STAC2 YES1 YES1 FYB1 FYB1 VAV3 VAV3 DOCK3 DOCK3 SASH1 SASH1 MPP2 MPP2 CASS4 CASS4 ARHGEF16 ARHGEF16 ARHGEF19 ARHGEF19 FGR FGR LCK LCK FYB2 FYB2 EPS8L3 EPS8L3 RUSC1 RUSC1 SPTA1 SPTA1 NCF2 NCF2 MAP3K21 MAP3K21 STAM STAM NEBL NEBL DLG5 DLG5 ZDHHC6 ZDHHC6 DOCK1 DOCK1 MAPK8IP1 MAPK8IP1 PACSIN3 PACSIN3 SHANK2 SHANK2 ARHGAP42 ARHGAP42 ARHGAP32 ARHGAP32 EPS8 EPS8 STAC3 STAC3 EFS EFS FUT8 FUT8 MPP5 MPP5 MAP3K9 MAP3K9 PPP1R13B PPP1R13B TJP1 TJP1 MYO1E MYO1E CSK CSK SNX33 SNX33 SH3GL3 SH3GL3 CASKIN1 CASKIN1 PPL PPL DLG4 DLG4 TNK1 TNK1 GAS7 GAS7 ARHGAP27 ARHGAP27 SKAP1 SKAP1 ABI3 ABI3 GRB2 GRB2 CASKIN2 CASKIN2 EVPL EVPL TJP3 TJP3 SH3GL1 SH3GL1 VAV1 VAV1 PRAM1 PRAM1 PIK3R2 PIK3R2 ARHGAP33 ARHGAP33 MAP3K10 MAP3K10 PPP1R13L PPP1R13L EPS8L1 EPS8L1 ITSN2 ITSN2 PEX13 PEX13 NCK2 NCK2 BIN1 BIN1 MYO7B MYO7B ARHGEF4 ARHGEF4 NGEF NGEF HCK HCK SLA2 SLA2 PLCG1 PLCG1 SRMS SRMS UBASH3A UBASH3A BAIAP2L2 BAIAP2L2 GRAP2 GRAP2 SGSM3 SGSM3 PACSIN2 PACSIN2 STAC STAC NCKIPSD NCKIPSD HCLS1 HCLS1 NCK1 NCK1 CK820_G0024137 CK820_G0024137 ARHGAP10 ARHGAP10 SH3RF1 SH3RF1 SORBS2 SORBS2 TRIO TRIO SNX18 SNX18 RASA1 RASA1 ARHGAP26 ARHGAP26 SH3TC2 SH3TC2 ARHGEF37 ARHGEF37 ITK ITK DOCK2 DOCK2 DSP DSP PACSIN1 PACSIN1 FRK FRK AHI1 AHI1 DBNL DBNL NCF1 NCF1 ARHGEF5 ARHGEF5 SORBS3 SORBS3 ASAP1 ASAP1 PLEC PLEC FNBP1 FNBP1 BTK BTK MPP1 MPP1 PRMT2 PRMT2 MPP3 MPP3 AMPH AMPH SASH3 SASH3 BAIAP2L1 BAIAP2L1 TSPOAP1 TSPOAP1 SRGAP1 SRGAP1 MATK MATK LASP1 LASP1 ARHGEF6 ARHGEF6 MPP7 MPP7 CACNB2 CACNB2 ABI1 ABI1 FCHSD1 FCHSD1 SH3RF2 SH3RF2 SH3BP4 SH3BP4 LYN LYN CRKL CRKL SRGAP3 SRGAP3 CASK CASK BLK BLK MPP4 MPP4 MYO1F MYO1F RUSC2 RUSC2 MAPK8IP2 MAPK8IP2 SRGAP2 SRGAP2 OTOR OTOR SH3D21 SH3D21 CACNB4 CACNB4 MIA2 MIA2 ARHGEF7 ARHGEF7 PTK6 PTK6 MIA MIA SH3PXD2B SH3PXD2B MACF1 MACF1 SLA SLA SHANK3 SHANK3 LOC101059173 LOC101059173 TJP2 TJP2 BAIAP2 BAIAP2 SPTAN1 SPTAN1 SNX9 SNX9 SHANK1 SHANK1 DLG1 DLG1 FNBP1L FNBP1L OBSCN OBSCN DOCK5 DOCK5 UBASH3B UBASH3B DLG3 DLG3 NOXA1 NOXA1 TEC TEC EPS8L2 EPS8L2 ABL1 ABL1 NEB NEB ABI2 ABI2 NPHP1 NPHP1 NCF4 NCF4 CK820_G0050194 CK820_G0050194 DOCK4 DOCK4 ARHGAP12 ARHGAP12 GRAPL GRAPL STAM2 STAM2 MYO7A MYO7A PLCG2 PLCG2 SRC SRC PIK3R1 PIK3R1 FYN FYN MPP6 MPP6 TP53BP2 TP53BP2 SH3PXD2A SH3PXD2A MIA3 MIA3 TRIP10 TRIP10 SH3D19 SH3D19 BCAR1 BCAR1 OSTF1 OSTF1 NOXO1 NOXO1 SH3TC1 SH3TC1 SH3GL2 SH3GL2 DNMBP DNMBP CTTN CTTN CRK CRK ITSN1 ITSN1 SH3YL1 SH3YL1 ASAP2 ASAP2 VAV2 VAV2 ARHGAP9 ARHGAP9 SKAP2 SKAP2 CD2AP CD2AP KALRN KALRN TXK TXK CACNB1 CACNB1 SH3GLB2-2 SH3GLB2-2 RIMBP2 RIMBP2 MACC1 MACC1 MCF2L-2 MCF2L-2 CACNB3 CACNB3 SORBS1 SORBS1 NOSTRIN NOSTRIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGAP4Rho GTPase activating protein 4. (986 aa)
MCF2LMCF2L isoform 9. (1202 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
ARHGEF26Src homology 3 domain-containing guanine nucleotide exchange factor. (871 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
FCHSD2FCH and double SH3 domains 2. (764 aa)
MYO15BMYO15B isoform 5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3036 aa)
ITSN1-2ITSN1 isoform 7. (1716 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (394 aa)
ARHGEF9ARHGEF9 isoform 17. (587 aa)
DSTDST isoform 9. (7462 aa)
TNK2TNK2 isoform 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
YES1Tyrosine-protein kinase. (558 aa)
FYB1FYB1 isoform 3. (839 aa)
VAV3VAV3 isoform 2. (927 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2030 aa)
SASH1SAM and SH3 domain containing 1. (1251 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (597 aa)
CASS4CASS4 isoform 2. (812 aa)
ARHGEF16ARHGEF16 isoform 1. (701 aa)
ARHGEF19Rho guanine nucleotide exchange factor (GEF) 19. (804 aa)
FGRTyrosine-protein kinase. (529 aa)
LCKTyrosine-protein kinase. (539 aa)
FYB2FYN binding protein 2. (728 aa)
EPS8L3EPS8L3 isoform 1. (594 aa)
RUSC1RUN and SH3 domain containing 1. (902 aa)
SPTA1SPTA1 isoform 1. (2419 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1036 aa)
STAMSignal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (540 aa)
NEBLNEBL isoform 5. (1014 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
ZDHHC6Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (413 aa)
DOCK1DOCK1 isoform 1; Belongs to the DOCK family. (1854 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (711 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1849 aa)
ARHGAP42Rho GTPase activating protein 42. (874 aa)
ARHGAP32ARHGAP32 isoform 2. (2095 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
EFSEmbryonal Fyn-associated substrate. (560 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. (575 aa)
MPP5Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (675 aa)
MAP3K9MAP3K9 isoform 3. (1119 aa)
PPP1R13BProtein phosphatase 1, regulatory (Inhibitor) subunit 13B. (1090 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1748 aa)
MYO1EMYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
CSKTyrosine-protein kinase. (450 aa)
SNX33Sorting nexin. (574 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (355 aa)
CASKIN1CASK interacting protein 1. (1430 aa)
PPLPPL isoform 2. (1756 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
TNK1TNK1 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (661 aa)
GAS7Growth arrest-specific 7. (476 aa)
ARHGAP27ARHGAP27 isoform 5. (890 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
ABI3ABI3 isoform 1. (366 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CASKIN2CASK interacting protein 2. (1202 aa)
EVPLEVPL isoform 2. (2055 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (928 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
PRAM1PML-RARA regulated adaptor molecule 1. (646 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
ARHGAP33Rho GTPase activating protein 33. (1142 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (954 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (828 aa)
EPS8L1EPS8L1 isoform 2. (718 aa)
ITSN2ITSN2 isoform 1. (1684 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
NCK2Cytoplasmic protein. (380 aa)
BIN1Bridging integrator 1. (597 aa)
MYO7BMYO7B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (1876 aa)
NGEFNeuronal guanine nucleotide exchange factor. (710 aa)
HCKTyrosine-protein kinase. (526 aa)
SLA2Src like adaptor 2. (261 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
SRMSTyrosine-protein kinase. (447 aa)
UBASH3AUbiquitin associated and SH3 domain containing A. (661 aa)
BAIAP2L2BAIAP2L2 isoform 1. (518 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
SGSM3Small G protein signaling modulator 3. (749 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (486 aa)
STACSH3 and cysteine rich domain. (402 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
NCK1Cytoplasmic protein. (377 aa)
CK820_G0024137ARHGEF38 isoform 4. (547 aa)
ARHGAP10Rho GTPase activating protein 10. (786 aa)
SH3RF1SH3 domain containing ring finger 1. (888 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3096 aa)
SNX18Sorting nexin. (591 aa)
RASA1RAS p21 protein activator (GTPase activating protein) 1. (1047 aa)
ARHGAP26Rho GTPase activating protein 26. (814 aa)
SH3TC2SH3TC2 isoform 8. (1288 aa)
ARHGEF37ARHGEF37 isoform 2. (817 aa)
ITKTyrosine-protein kinase. (620 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
DSPDSP isoform 1. (2871 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
FRKTyrosine-protein kinase. (505 aa)
AHI1Abelson helper integration site 1. (1196 aa)
DBNLDBNL isoform 5. (439 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ARHGEF5ARHGEF5 isoform 2. (1597 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
PLECPLEC isoform 2. (4684 aa)
FNBP1Formin binding protein 1. (620 aa)
BTKBTK isoform 2. (693 aa)
MPP1Membrane protein, palmitoylated 1, 55kDa; Belongs to the MAGUK family. (466 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (433 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (610 aa)
AMPHAMPH isoform 1. (669 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
BAIAP2L1BAI1-associated protein 2-like 1. (511 aa)
TSPOAP1TSPO associated protein 1. (1867 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
MATKTyrosine-protein kinase. (508 aa)
LASP1LIM and SH3 protein 1. (261 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (783 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
ABI1Abl interactor 1. (508 aa)
FCHSD1FCH and double SH3 domains 1. (690 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
SH3BP4SH3 domain-binding protein 4. (963 aa)
LYNTyrosine-protein kinase. (512 aa)
CRKLV-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1099 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (921 aa)
BLKTyrosine-protein kinase. (505 aa)
MPP4MPP4 isoform 2; Belongs to the MAGUK family. (636 aa)
MYO1FMYO1F isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (988 aa)
RUSC2RUN and SH3 domain containing 2. (1516 aa)
MAPK8IP2MAPK8IP2 isoform 2. (824 aa)
SRGAP2SRGAP2 isoform 1. (1071 aa)
OTOROTOR isoform 1. (128 aa)
SH3D21SH3D21 isoform 1. (773 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
MIA2MIA SH3 domain ER export factor 2. (1412 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
PTK6Tyrosine-protein kinase. (451 aa)
MIAMIA-RAB4B isoform 1. (183 aa)
SH3PXD2BSH3 and PX domains 2B. (911 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
SLASrc like adaptor. (316 aa)
SHANK3SHANK3 isoform 2. (1744 aa)
LOC101059173RIMBP3B isoform 1. (1639 aa)
TJP2Tight junction protein 2; Belongs to the MAGUK family. (1249 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
SPTAN1SPTAN1 isoform 9. (2498 aa)
SNX9Sorting nexin. (596 aa)
SHANK1SHANK1 isoform 3. (2161 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
FNBP1LFormin binding protein 1 like. (611 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8919 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1881 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (853 aa)
NOXA1NOXA1 isoform 2. (87 aa)
TECTyrosine-protein kinase. (631 aa)
EPS8L2EPS8L2 isoform 15. (607 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
NEBNEB isoform 5. (8417 aa)
ABI2Abl interactor 2. (513 aa)
NPHP1NPHP1 isoform 1. (729 aa)
NCF4Neutrophil cytosolic factor 4. (368 aa)
CK820_G0050194GRAP isoform 1. (153 aa)
DOCK4DOCK4 isoform 6; Belongs to the DOCK family. (2011 aa)
ARHGAP12Rho GTPase activating protein 12. (846 aa)
GRAPLGRAP isoform 4. (100 aa)
STAM2Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (525 aa)
MYO7AMYO7A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2222 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
SRCTyrosine-protein kinase. (542 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
FYNTyrosine-protein kinase. (537 aa)
MPP6Membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (582 aa)
TP53BP2Tumor protein p53 binding protein 2. (1137 aa)
SH3PXD2ASH3 and PX domains 2A. (1133 aa)
MIA3MIA3 isoform 1. (1983 aa)
TRIP10Thyroid hormone receptor interactor 10. (601 aa)
SH3D19SH3 domain containing 19. (1047 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
OSTF1Osteoclast stimulating factor 1. (214 aa)
NOXO1NOXO1 isoform 6. (482 aa)
SH3TC1SH3TC1 isoform 2. (1336 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
DNMBPDynamin binding protein. (1577 aa)
CTTNCTTN isoform 2. (634 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
ITSN1ITSN1 isoform 4. (1721 aa)
SH3YL1SH3 and SYLF domain containing 1. (416 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ARHGAP9Rho GTPase activating protein 9. (833 aa)
SKAP2Src kinase associated phosphoprotein 2. (359 aa)
CD2APCD2-associated protein. (650 aa)
KALRNKalirin RhoGEF kinase. (2986 aa)
TXKTyrosine-protein kinase. (527 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
SH3GLB2-2SH3 domain containing GRB2 like, endophilin B2. (404 aa)
RIMBP2RIMS binding protein 2. (1362 aa)
MACC1MET transcriptional regulator MACC1. (852 aa)
MCF2L-2MCF2L isoform 7. (395 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
NOSTRINNitric oxide synthase trafficking. (563 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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