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CATSPER4 CATSPER4 KCNC3 KCNC3 RYR1 RYR1 RYR3 RYR3 TRPM3 TRPM3 KCNC4 KCNC4 TRPM6 TRPM6 KCNQ1 KCNQ1 KCNH6 KCNH6 HVCN1 HVCN1 KCNA7 KCNA7 TRPV4 TRPV4 TRPC1 TRPC1 CACNA1A CACNA1A CNGA3 CNGA3 CK820_G0013720 CK820_G0013720 KCNC2 KCNC2 CACNA1D CACNA1D TRPM8 TRPM8 CACNA1S CACNA1S SCN2A SCN2A KCNH8 KCNH8 KCNQ5 KCNQ5 SCN5A SCN5A KCND2 KCND2 TRPM2 TRPM2 CACNA1G CACNA1G KCNG1 KCNG1 TRPM1 TRPM1 RYR2 RYR2 TPCN2 TPCN2 KCNA2 KCNA2 KCNMA1 KCNMA1 KCNS2 KCNS2 KCND3 KCND3 CACNA1I CACNA1I KCNU1 KCNU1 SCN3A SCN3A TRPC3 TRPC3 KCNH5 KCNH5 KCNF1 KCNF1 KCNA6 KCNA6 CNGA4 CNGA4 KCNH2 KCNH2 TRPA1 TRPA1 TRPC4 TRPC4 TRPM5 TRPM5 SCN10A SCN10A TRPV6 TRPV6 SCN8A SCN8A SCN7A SCN7A CNGA2 CNGA2 TRPC5 TRPC5 CACNA1F CACNA1F KCND1 KCND1 CACNA1B CACNA1B KCNV2 KCNV2 KCNQ3 KCNQ3 KCNV1 KCNV1 KCNB2 KCNB2 TRPV5-2 TRPV5-2 ITPR3 ITPR3 TRPC7 TRPC7 CATSPER3 CATSPER3 HCN1 HCN1 CNGA1-2 CNGA1-2 SCN11A SCN11A ITPR1 ITPR1 ITPR2 ITPR2 KCNQ2 KCNQ2 KCNB1 KCNB1 KCNS1 KCNS1 SCN9A SCN9A SCN1A SCN1A KCNH7 KCNH7 KCNG3 KCNG3 KCNS3 KCNS3 TRPM4 TRPM4 KCNG2 KCNG2 SCN4A SCN4A KCNH4 KCNH4 TRPV2 TRPV2 TRPV1 TRPV1 TRPV3 TRPV3 KCNG4 KCNG4 CACNA1H CACNA1H HCN4 HCN4 TRPM7 TRPM7 LOC107966461 LOC107966461 NALCN NALCN TPCN1 TPCN1 KCNH3 KCNH3 KCNA5 KCNA5 KCNA1 KCNA1 CACNA1C CACNA1C TRPC6 TRPC6 CATSPER1 CATSPER1 KCNC1 KCNC1 CACNA1E CACNA1E HCN3 HCN3 KCNA3 KCNA3 KCNA10 KCNA10 KCNQ4 KCNQ4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CATSPER4Cation channel sperm associated 4. (464 aa)
KCNC3KCNC3 isoform 4; Belongs to the potassium channel family. (742 aa)
RYR1RYR1 isoform 3. (5037 aa)
RYR3Ryanodine receptor 3. (4873 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1711 aa)
KCNC4KCNC4 isoform 6; Belongs to the potassium channel family. (644 aa)
TRPM6TRPM6 isoform 2. (2017 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
HVCN1Hydrogen voltage-gated channel 1. (274 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (456 aa)
TRPV4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2504 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (698 aa)
CK820_G0013720HCN2 isoform 1. (847 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
TRPM8TRPM8 isoform 2. (1104 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
KCND2Potassium voltage-gated channel, Shal-related subfamily, member 2; Belongs to the potassium channel family. (630 aa)
TRPM2TRPM2 isoform 4. (1393 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (513 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
RYR2RYR2 isoform 1. (4941 aa)
TPCN2Two pore segment channel 2. (752 aa)
KCNA2KCNA2 isoform 1; Belongs to the potassium channel family. (356 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
KCND3Potassium voltage-gated channel, Shal-related subfamily, member 3; Belongs to the potassium channel family. (655 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2223 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
KCNF1KCNF1 isoform 1; Belongs to the potassium channel family. (506 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (529 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
TRPC4Transient receptor potential cation channel, subfamily C, member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1172 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6. (765 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1682 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1984 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2312 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (545 aa)
KCNQ3KCNQ3 isoform 1; Belongs to the potassium channel family. (843 aa)
KCNV1KCNV1 isoform 1; Belongs to the potassium channel family. (502 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
TRPV5-2Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
HCN1HCN1 isoform 1. (886 aa)
CNGA1-2Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1792 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
KCNQ2KCNQ2 isoform 7; Belongs to the potassium channel family. (871 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. (526 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1988 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1196 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (436 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (467 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1017 aa)
TRPV2Transient receptor potential cation channel, subfamily V, member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (519 aa)
CACNA1HCACNA1H isoform 1. (2240 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
TRPM7Transient receptor potential cation channel, subfamily M, member 7. (1865 aa)
LOC107966461CATSPER2 isoform 1. (563 aa)
NALCNSodium leak channel, non-selective. (1738 aa)
TPCN1TPCN1 isoform 2. (888 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa)
KCNA1Potassium voltage-gated channel, shaker-related subfamily, member 1 (Episodic ataxia with myokymia); Belongs to the potassium channel family. (495 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
TRPC6Transient receptor potential cation channel, subfamily C, member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
CATSPER1Cation channel sperm associated 1. (780 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (774 aa)
KCNA3KCNA3 isoform 1; Belongs to the potassium channel family. (575 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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