STRINGSTRING
NCOR2 NCOR2 HOXD3 HOXD3 TIGD5 TIGD5 VAX1 VAX1 HOXD4 HOXD4 MTA3 MTA3 HOXB8 HOXB8 CUX2 CUX2 HOXD1 HOXD1 POU5F1B POU5F1B CUX1 CUX1 PAX3 PAX3 PAX2 PAX2 SHOX2 SHOX2 MIER1 MIER1 ESX1 ESX1 HOMEZ HOMEZ CASP8AP2 CASP8AP2 ZEB2 ZEB2 POU6F2 POU6F2 SATB1 SATB1 EN2-2 EN2-2 NKX2-1 NKX2-1 LHX8 LHX8 MEIS3 MEIS3 TLX1 TLX1 PKNOX1 PKNOX1 CDC5L CDC5L HOXC5 HOXC5 MIXL1 MIXL1 ARX ARX CDX2 CDX2 SIX1 SIX1 SHOX SHOX JRK JRK JRKL JRKL NKX3-2 NKX3-2 TIGD6 TIGD6 DBX1 DBX1 CERS6 CERS6 HOXA3 HOXA3 IRX5 IRX5 PBX3 PBX3 HMX1 HMX1 HOXA10 HOXA10 MEIS1 MEIS1 ONECUT3 ONECUT3 RHOXF1 RHOXF1 HOPX HOPX PAX6 PAX6 GSC2 GSC2 TIGD2 TIGD2 CK820_G0042706 CK820_G0042706 MTA2 MTA2 UNCX UNCX LHX3 LHX3 POGZ POGZ HOXB3 HOXB3 ZEB1 ZEB1 NKX1-2 NKX1-2 KDM1A KDM1A HDX HDX PBX1 PBX1 DUXB DUXB ANHX ANHX NKX1-1 NKX1-1 POU3F4 POU3F4 HOXD12 HOXD12 TIGD1 TIGD1 HOXA6 HOXA6 DLX6 DLX6 CERS3 CERS3 EMX1 EMX1 HOXD11 HOXD11 NOTO NOTO MSX1 MSX1 HOXD8 HOXD8 LHX1 LHX1 TERF2 TERF2 NKX6-3 NKX6-3 ZHX2 ZHX2 ZFHX2 ZFHX2 POU3F1 POU3F1 RCOR1 RCOR1 LBX2 LBX2 POGK POGK PROX1 PROX1 NANOGNB NANOGNB LBX1 LBX1 PAX5 PAX5 EN1 EN1 PBX4 PBX4 SIX5 SIX5 CENPB CENPB CK820_G0042272 CK820_G0042272 DUXA DUXA HOXA13-2 HOXA13-2 PHOX2A PHOX2A DNAJC2 DNAJC2 MNX1 MNX1 BARX1 BARX1 DMBX1 DMBX1 TERF1 TERF1 HOXB9 HOXB9 SIX4 SIX4 HOXA4 HOXA4 CERS2 CERS2 ZFHX4 ZFHX4 DLX1 DLX1 LOC107966504 LOC107966504 TGIF2LX TGIF2LX CDX4 CDX4 SNAPC4 SNAPC4 BARHL1 BARHL1 PRRX2 PRRX2 LMX1B LMX1B LHX2 LHX2 ZHX1 ZHX1 NKX2-6 NKX2-6 GBX1 GBX1 NOBOX NOBOX PAX4 PAX4 DLX5 DLX5 DMTF1 DMTF1 EVX1 EVX1 HOXA11 HOXA11 HOXA7 HOXA7 HOXA5 HOXA5 HOXA2 HOXA2 HOXA1 HOXA1 MEOX2 MEOX2 MYB MYB TRERF1 TRERF1 PBX2 PBX2 POU5F1 POU5F1 KDM1B KDM1B PROP1 PROP1 MSX2 MSX2 NKX2-5 NKX2-5 TLX3 TLX3 CDX1 CDX1 PITX1 PITX1 OTP OTP BDP1 BDP1 MIER3 MIER3 ISL1 ISL1 IRX1 IRX1 IRX2 IRX2 TIGD4 TIGD4 POU4F2 POU4F2 SMARCA5 SMARCA5 PITX2 PITX2 NKX6-1 NKX6-1 GSX2 GSX2 PHOX2B PHOX2B TADA2B TADA2B ARGFX ARGFX POU1F1 POU1F1 HESX1 HESX1 SMARCC1 SMARCC1 ISX ISX ADNP ADNP MYBL2 MYBL2 PAX1 PAX1 NKX2-2 NKX2-2 NKX2-4 NKX2-4 GBX2 GBX2 HOXD10 HOXD10 HOXD13 HOXD13 EVX2 EVX2 DLX2 DLX2 TLX2 TLX2 VAX2 VAX2 OTX1 OTX1 SIX2 SIX2 SIX3 SIX3 CRX CRX ZNF541 ZNF541 CERS4 CERS4 RAX2 RAX2 ADNP2 ADNP2 RAX RAX TGIF1 TGIF1 DLX3 DLX3 DLX4 DLX4 HOXB13 HOXB13 HOXB7 HOXB7 HOXB6 HOXB6 HOXB5 HOXB5 HOXB4 HOXB4 HOXB2 HOXB2 HOXB1 HOXB1 MEOX1 MEOX1 TADA2A TADA2A TERF2IP TERF2IP ZFHX3 ZFHX3 TERB1 TERB1 IRX6 IRX6 IRX3 IRX3 TIGD7 TIGD7 ISL2 ISL2 MEIS2 MEIS2 GSC GSC PROX2 PROX2 VSX2 VSX2 ELMSAN1 ELMSAN1 SIX6 SIX6 OTX2 OTX2 MIS18BP1 MIS18BP1 PAX9 PAX9 NKX2-8 NKX2-8 PDX1 PDX1 GSX1 GSX1 LHX5 LHX5 ALX1 ALX1 HOXC6 HOXC6 HOXC8 HOXC8 HOXC9 HOXC9 HOXC11 HOXC11 HOXC12 HOXC12 HOXC13 HOXC13 POU6F1 POU6F1 CERS5 CERS5 DBX2 DBX2 NANOG NANOG BARX2 BARX2 PKNOX2 PKNOX2 BSX BSX POU2F3 POU2F3 TIGD3 TIGD3 RCOR2 RCOR2 VENTX VENTX NKX6-2 NKX6-2 EMX2 EMX2 PITX3 PITX3 HHEX HHEX DRGX DRGX MKX MKX DNAJC1 DNAJC1 HLX HLX RCOR3 RCOR3 LHX4 LHX4 PRRX1 PRRX1 LMX1A LMX1A ALX3 ALX3 BARHL2 BARHL2 POU4F1 POU4F1 PAX7 PAX7 RERE RERE NKX2-3 NKX2-3 POU3F3 POU3F3 MIER2 MIER2 NCOR1 NCOR1 HMBOX1 HMBOX1 ZZZ3 ZZZ3 POU2F1 POU2F1 HMX3 HMX3 LHX9 LHX9 HOXD9 HOXD9 SATB2 SATB2 POU2F2 POU2F2 ONECUT2 ONECUT2 NKX3-1 NKX3-1 MYBL1 MYBL1 SMARCA1 SMARCA1 HNF1B HNF1B SMARCC2 SMARCC2 MTA1 MTA1 ALX4 ALX4 HOXC4 HOXC4 IRX4 IRX4 ONECUT1 ONECUT1 HMX2 HMX2 CPHXL CPHXL MYSM1 MYSM1 VSX1 VSX1 HNF1A HNF1A LEUTX LEUTX LHX6 LHX6 PAX8 PAX8 ZHX3 ZHX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCOR2Nuclear receptor corepressor 2. (2514 aa)
HOXD3HOXD3 isoform 3. (432 aa)
TIGD5Tigger transposable element derived 5. (643 aa)
VAX1Ventral anterior homeobox 1. (334 aa)
HOXD4Homeobox protein Hox-D4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Deformed subfamily. (255 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
HOXB8HOXB8 isoform 1. (243 aa)
CUX2Homeobox protein cut-like. (1489 aa)
HOXD1HOXD1 isoform 1. (328 aa)
POU5F1BPOU domain protein. (359 aa)
CUX1Homeobox protein cut-like. (1515 aa)
PAX3PAX3 isoform 4. (505 aa)
PAX2PAX2 isoform 1. (417 aa)
SHOX2SHOX2 isoform 2. (343 aa)
MIER1Mesoderm induction early response 1 homolog. (565 aa)
ESX1ESX homeobox 1. (431 aa)
HOMEZHomeobox and leucine zipper encoding. (548 aa)
CASP8AP2CASP8AP2 isoform 4. (2049 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
POU6F2POU domain protein. (708 aa)
SATB1DNA-binding protein SATB. (795 aa)
EN2-2Homeobox protein engrailed-like. (336 aa)
NKX2-1NKX2-1 isoform 1. (401 aa)
LHX8LHX8 isoform 2. (377 aa)
MEIS3MEIS3 isoform 5. (463 aa)
TLX1T cell leukemia homeobox 1. (330 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
CDC5LCDC5 cell division cycle 5-like. (802 aa)
HOXC5HOXC5 isoform 1. (222 aa)
MIXL1Mix paired-like homeobox. (232 aa)
ARXARX isoform 1. (559 aa)
CDX2Caudal type homeobox 2. (313 aa)
SIX1SIX homeobox 1. (284 aa)
SHOXShort stature homeobox. (292 aa)
JRKJrk helix-turn-helix protein. (556 aa)
JRKLJerky homolog-like. (524 aa)
NKX3-2NKX3-2 isoform 1. (333 aa)
TIGD6Tigger transposable element derived 6. (521 aa)
DBX1Developing brain homeobox 1. (345 aa)
CERS6Ceramide synthase 6. (392 aa)
HOXA3HOXA3 isoform 3. (443 aa)
IRX5Iroquois homeobox 5. (483 aa)
PBX3PBX homeobox 3. (455 aa)
HMX1H6 family homeobox 1. (348 aa)
HOXA10HOXA10 isoform 2. (410 aa)
MEIS1MEIS1 isoform 7. (465 aa)
ONECUT3One cut domain family member. (472 aa)
RHOXF1RHOXF1 isoform 1. (184 aa)
HOPXHOPX isoform 3. (112 aa)
PAX6PAX6 isoform 13. (436 aa)
GSC2Goosecoid homeobox 2. (205 aa)
TIGD2Tigger transposable element derived 2. (525 aa)
CK820_G0042706T0150490 isoform 1. (400 aa)
MTA2Metastasis associated 1 family, member 2. (673 aa)
UNCXUNCX isoform 1. (531 aa)
LHX3LHX3 isoform 2. (402 aa)
POGZPOGZ isoform 8. (1410 aa)
HOXB3HOXB3 isoform 13. (431 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1127 aa)
NKX1-2NKX1-2 isoform 1. (310 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
HDXHighly divergent homeobox. (690 aa)
PBX1Pre-B-cell leukemia homeobox 1. (486 aa)
DUXBDouble homeobox B. (345 aa)
ANHXAnomalous homeobox. (379 aa)
NKX1-1NKX1-1 isoform 1. (408 aa)
POU3F4POU domain protein. (361 aa)
HOXD12HOXD12 isoform 1. (270 aa)
TIGD1Tigger transposable element derived 1. (591 aa)
HOXA6HOXA6 isoform 2. (233 aa)
DLX6DLX6 isoform 1. (295 aa)
CERS3CERS3 isoform 1. (383 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
HOXD11HOXD11 isoform 2. (339 aa)
NOTONotochord homeobox. (251 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
HOXD8Homeobox protein Hox-D8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (289 aa)
LHX1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
NKX6-3NKX6-3 isoform 1. (265 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
ZFHX2ZFHX2 isoform 1. (2572 aa)
POU3F1POU domain protein. (451 aa)
RCOR1REST corepressor 1. (482 aa)
LBX2Ladybird homeobox 2. (198 aa)
POGKPogo transposable element derived with KRAB domain. (609 aa)
PROX1Prospero homeobox 1. (737 aa)
NANOGNBNANOGNB isoform 1. (189 aa)
LBX1Ladybird homeobox 1. (281 aa)
PAX5PAX5 isoform 1. (391 aa)
EN1Homeobox protein engrailed-like. (396 aa)
PBX4PBX homeobox 4. (374 aa)
SIX5SIX homeobox 5. (738 aa)
CENPBCentromere protein B. (599 aa)
CK820_G0042272TPRX1 isoform 2. (510 aa)
DUXADouble homeobox A. (204 aa)
HOXA13-2HOXA13 isoform 1. (388 aa)
PHOX2APaired like homeobox 2A. (284 aa)
DNAJC2DnaJ heat shock protein family (Hsp40) member C2. (621 aa)
MNX1Motor neuron and pancreas homeobox 1. (398 aa)
BARX1BARX homeobox 1. (254 aa)
DMBX1Diencephalon/mesencephalon homeobox 1. (377 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (439 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
SIX4SIX homeobox 4. (781 aa)
HOXA4HOXA4 isoform 1. (320 aa)
CERS2LAG1 homolog, ceramide synthase 2. (380 aa)
ZFHX4Zinc finger homeobox 4. (3615 aa)
DLX1Distal-less homeobox 1. (255 aa)
LOC107966504RHOXF2 isoform 1. (281 aa)
TGIF2LXHomeobox protein TGIF2LX; May have a transcription role in testis; Belongs to the TALE/TGIF homeobox family. (241 aa)
CDX4Caudal type homeobox 4. (284 aa)
SNAPC4SNAPC4 isoform 2. (1442 aa)
BARHL1BarH like homeobox 1. (327 aa)
PRRX2Paired related homeobox 2. (253 aa)
LMX1BLIM homeobox transcription factor 1 beta. (402 aa)
LHX2LHX2 isoform 1. (406 aa)
ZHX1Zinc fingers and homeoboxes protein 1; Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins (By similarity). (854 aa)
NKX2-6NKX2-6 isoform 1. (301 aa)
GBX1Gastrulation brain homeobox 1. (363 aa)
NOBOXNOBOX isoform 1. (690 aa)
PAX4PAX4 isoform 1. (351 aa)
DLX5Distal-less homeobox 5. (289 aa)
DMTF1DMTF1 isoform 19. (759 aa)
EVX1EVX1 isoform 2. (407 aa)
HOXA11HOXA11 isoform 2. (313 aa)
HOXA7Homeobox protein Hox-A7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (230 aa)
HOXA5HOXA5 isoform 1. (270 aa)
HOXA2HOXA2 isoform 1. (376 aa)
HOXA1HOXA1 isoform 2. (335 aa)
MEOX2Mesenchyme homeobox 2. (302 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
TRERF1Transcriptional regulating factor 1. (1219 aa)
PBX2Pre-B-cell leukemia homeobox 2. (430 aa)
POU5F1POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). (360 aa)
KDM1BKDM1B isoform 4. (922 aa)
PROP1PROP paired-like homeobox 1. (226 aa)
MSX2Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity); Belongs to the Msh homeobox family. (267 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
TLX3TLX3 isoform 1. (291 aa)
CDX1CDX1 isoform 1. (265 aa)
PITX1Homeobox protein. (314 aa)
OTPOrthopedia homeobox. (325 aa)
BDP1B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB. (2624 aa)
MIER3MIER family member 3. (549 aa)
ISL1ISL LIM homeobox 1. (349 aa)
IRX1Iroquois homeobox 1. (480 aa)
IRX2Iroquois homeobox 2. (471 aa)
TIGD4TIGD4 isoform 1. (512 aa)
POU4F2POU domain protein. (406 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
PITX2Homeobox protein. (324 aa)
NKX6-1NKX6-1 isoform 2. (367 aa)
GSX2GSX2 isoform 2. (304 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
TADA2BTranscriptional adapter. (420 aa)
ARGFXArginine-fifty homeobox. (315 aa)
POU1F1POU domain protein. (317 aa)
HESX1Homeobox expressed in ES cells 1; Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity). (185 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
ISXIntestine specific homeobox. (245 aa)
ADNPActivity-dependent neuroprotector homeobox. (1102 aa)
MYBL2V-myb myeloblastosis viral oncogene homolog (Avian)-like 2. (699 aa)
PAX1PAX1 isoform 1. (457 aa)
NKX2-2NKX2-2 isoform 1. (273 aa)
NKX2-4NKX2-4 isoform 1. (354 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
HOXD10Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (410 aa)
HOXD13HOXD13 isoform 1. (344 aa)
EVX2Even-skipped homeobox 2. (476 aa)
DLX2Distal-less homeobox 2. (328 aa)
TLX2T-cell leukemia homeobox 2. (284 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
SIX2SIX homeobox 2. (291 aa)
SIX3SIX homeobox 3. (331 aa)
CRXCone-rod homeobox. (299 aa)
ZNF541Zinc finger protein 541. (1355 aa)
CERS4CERS4 isoform 1. (394 aa)
RAX2Retina and anterior neural fold homeobox protein 2; May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter (By similarity). (184 aa)
ADNP2ADNP homeobox 2. (1125 aa)
RAXRetina and anterior neural fold homeobox. (346 aa)
TGIF1Homeobox protein TGIF1; Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activitie [...] (401 aa)
DLX3Distal-less homeobox 3. (287 aa)
DLX4Distal-less homeobox 4. (240 aa)
HOXB13HOXB13 isoform 1. (284 aa)
HOXB7HOXB7 isoform 2. (217 aa)
HOXB6HOXB6 isoform 1. (224 aa)
HOXB5HOXB5 isoform 1. (269 aa)
HOXB4HOXB4 isoform 1. (251 aa)
HOXB2HOXB2 isoform 1. (356 aa)
HOXB1Homeobox protein Hox-B1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures (By similarity); Belongs to the Antp homeobox family. Labial subfamily. (301 aa)
MEOX1Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independen [...] (254 aa)
TADA2ATranscriptional adapter. (443 aa)
TERF2IPTelomeric repeat binding factor 2, interacting protein. (399 aa)
ZFHX3Zinc finger homeobox 3. (3688 aa)
TERB1Telomere repeat binding bouquet formation protein 1. (727 aa)
IRX6Iroquois homeobox 6. (445 aa)
IRX3Iroquois homeobox 3. (500 aa)
TIGD7Tigger transposable element derived 7. (549 aa)
ISL2ISL LIM homeobox 2. (359 aa)
MEIS2MEIS2 isoform 1. (477 aa)
GSCHomeobox protein goosecoid; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity); Belongs to the paired homeobox family. Bicoid subfamily. (257 aa)
PROX2Prospero homeobox 2. (592 aa)
VSX2VSX2 isoform 1. (380 aa)
ELMSAN1ELMSAN1 isoform 5. (1099 aa)
SIX6SIX homeobox 6. (246 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
MIS18BP1MIS18 binding protein 1. (1132 aa)
PAX9Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. (347 aa)
NKX2-8NKX2-8 isoform 1. (239 aa)
PDX1Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element [...] (283 aa)
GSX1GSX1 isoform 1. (264 aa)
LHX5LHX5 isoform 2. (402 aa)
ALX1ALX homeobox 1. (326 aa)
HOXC6HOXC6 isoform 1. (235 aa)
HOXC8HOXC8 isoform 1. (242 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
HOXC11HOXC11 isoform 1. (304 aa)
HOXC12HOXC12 isoform 1. (280 aa)
HOXC13HOXC13 isoform 1. (330 aa)
POU6F1POU domain protein. (611 aa)
CERS5LAG1 homolog, ceramide synthase 5. (391 aa)
DBX2Developing brain homeobox 2. (339 aa)
NANOGHomeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT] [...] (305 aa)
BARX2BARX homeobox 2. (279 aa)
PKNOX2PBX/knotted 1 homeobox 2. (472 aa)
BSXBrain specific homeobox. (233 aa)
POU2F3POU domain protein. (436 aa)
TIGD3Tigger transposable element derived 3. (471 aa)
RCOR2RCOR2 isoform 1. (318 aa)
VENTXVENTX isoform 1. (258 aa)
NKX6-2NKX6-2 isoform 1. (276 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
PITX3Homeobox protein. (302 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
MKXMohawk homeobox. (352 aa)
DNAJC1DNAJC1 isoform 2. (557 aa)
HLXH2.0-like homeobox. (493 aa)
RCOR3REST corepressor 3. (553 aa)
LHX4LHX4 isoform 1. (390 aa)
PRRX1Paired related homeobox 1. (245 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
ALX3ALX homeobox 3. (343 aa)
BARHL2BarH like homeobox 2. (387 aa)
POU4F1POU domain protein. (350 aa)
PAX7PAX7 isoform 2. (505 aa)
REREArginine-glutamic acid dipeptide (RE) repeats. (1566 aa)
NKX2-3NKX2-3 isoform 1. (366 aa)
POU3F3POU domain protein. (476 aa)
MIER2Mesoderm induction early response 1, family member 2. (536 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
HMBOX1Homeobox containing 1. (420 aa)
ZZZ3Zinc finger, ZZ-type containing 3. (903 aa)
POU2F1POU domain protein. (766 aa)
HMX3H6 family homeobox 3. (357 aa)
LHX9LHX9 isoform 2. (397 aa)
HOXD9HOXD9 isoform 1. (356 aa)
SATB2DNA-binding protein SATB. (733 aa)
POU2F2POU domain protein. (622 aa)
ONECUT2One cut domain family member. (504 aa)
NKX3-1NKX3-1 isoform 1. (234 aa)
MYBL1V-myb myeloblastosis viral oncogene homolog (Avian)-like 1. (754 aa)
SMARCA1SMARCA1 isoform 3. (1111 aa)
HNF1BHNF1 homeobox B. (557 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa)
MTA1Metastasis associated 1. (743 aa)
ALX4ALX homeobox 4. (411 aa)
HOXC4HOXC4 isoform 1. (264 aa)
IRX4IRX4 isoform 3. (543 aa)
ONECUT1One cut domain family member. (465 aa)
HMX2H6 family homeobox 2. (273 aa)
CPHXLCytoplasmic polyadenylated homeobox like. (405 aa)
MYSM1Myb-like, SWIRM and MPN domains 1. (828 aa)
VSX1Visual system homeobox 1. (365 aa)
HNF1AHNF1 homeobox A. (662 aa)
LEUTXLEUTX isoform 2. (198 aa)
LHX6LHX6 isoform 3. (428 aa)
PAX8PAX8 isoform 1. (456 aa)
ZHX3Zinc fingers and homeoboxes 3. (965 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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