41 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

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	CTH	Cystathionase (Cystathionine gamma-lyase). (405 aa)
	KYAT3	Cysteine conjugate-beta lyase 2. (454 aa)
	GOT1	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] (413 aa)
	OAT	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	SPTLC2	Serine palmitoyltransferase, long chain base subunit 2. (564 aa)
	HDC	Histidine decarboxylase. (662 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
	GPT2	Glutamic pyruvate transaminase (Alanine aminotransferase) 2. (523 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	TAT	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (888 aa)
	GAD1	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (594 aa)
	AGXT	Serine--pyruvate aminotransferase. (367 aa)
	ALAS1	5-aminolevulinate synthase. (640 aa)
	SEPSECS	O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (500 aa)
	ETNPPL	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (499 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	GPT	Glutamic--pyruvic transaminase. (496 aa)
	ACCSL	1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like. (568 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1020 aa)
	GCAT	Glycine C-acetyltransferase. (445 aa)
	SPTLC3	Serine palmitoyltransferase, long chain base subunit 3. (552 aa)
	SCLY	Selenocysteine lyase. (453 aa)
	CK820_G0055659	PDXDC1 isoform 1. (783 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	NFS1	NFS1 nitrogen fixation 1 homolog. (605 aa)
	KYAT1	Kynurenine aminotransferase 1. (516 aa)
	PHYKPL	Alanine-glyoxylate aminotransferase 2-like 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (568 aa)
	PDXDC1	PDXDC1 isoform 10. (809 aa)
	ALAS2	5-aminolevulinate synthase. (587 aa)
	SPTLC1	Aminotran_1_2 domain-containing protein. (463 aa)
	CK820_G0027673	GCAT isoform 4. (82 aa)
	CSAD	Cysteine sulfinic acid decarboxylase. (520 aa)
	DDC	Dopa decarboxylase. (489 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	GOT1L1	GOT1L1 isoform 1. (415 aa)
	GADL1	Glutamate decarboxylase like 1. (521 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	ABAT	ENSPTRP00000028475	ENSPTRP00000013232	Aminoadipate aminotransferase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
AADAT	AGXT	ENSPTRP00000028475	ENSPTRP00000022452	Aminoadipate aminotransferase.	Serine--pyruvate aminotransferase.	0.418
AADAT	AGXT2	ENSPTRP00000028475	ENSPTRP00000028785	Aminoadipate aminotransferase.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.426
AADAT	ETNPPL	ENSPTRP00000028475	ENSPTRP00000028096	Aminoadipate aminotransferase.	Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
AADAT	GOT1	ENSPTRP00000028475	ENSPTRP00000004968	Aminoadipate aminotransferase.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.461
AADAT	GOT2	ENSPTRP00000028475	ENSPTRP00000013976	Aminoadipate aminotransferase.	Aspartate aminotransferase.	0.428
AADAT	KYAT1	ENSPTRP00000028475	ENSPTRP00000063694	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.968
AADAT	KYAT3	ENSPTRP00000028475	ENSPTRP00000001612	Aminoadipate aminotransferase.	Cysteine conjugate-beta lyase 2.	0.935
AADAT	KYNU	ENSPTRP00000028475	ENSPTRP00000067734	Aminoadipate aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.	0.959
AADAT	PHYKPL	ENSPTRP00000028475	ENSPTRP00000067067	Aminoadipate aminotransferase.	Alanine-glyoxylate aminotransferase 2-like 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.401
ABAT	AADAT	ENSPTRP00000013232	ENSPTRP00000028475	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminoadipate aminotransferase.	0.401
ABAT	AGXT	ENSPTRP00000013232	ENSPTRP00000022452	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine--pyruvate aminotransferase.	0.556
ABAT	AGXT2	ENSPTRP00000013232	ENSPTRP00000028785	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.938
ABAT	CSAD	ENSPTRP00000013232	ENSPTRP00000083350	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Cysteine sulfinic acid decarboxylase.	0.524
ABAT	DDC	ENSPTRP00000013232	ENSPTRP00000091008	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dopa decarboxylase.	0.476
ABAT	GAD1	ENSPTRP00000013232	ENSPTRP00000021575	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family.	0.963
ABAT	GAD2	ENSPTRP00000013232	ENSPTRP00000092080	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase 2.	0.963
ABAT	GADL1	ENSPTRP00000013232	ENSPTRP00000093466	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase like 1.	0.950
ABAT	GOT1	ENSPTRP00000013232	ENSPTRP00000004968	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.748
ABAT	GOT1L1	ENSPTRP00000013232	ENSPTRP00000093290	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	GOT1L1 isoform 1.	0.449