(14 nodes) Pre-ATP-grasp domain superfamily network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYN2	SYN2 isoform 1. (570 aa)
	SYN3	SYN3 isoform 1. (580 aa)
	CPS1	Carbamoyl-phosphate synthase 1, mitochondrial. (1507 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2229 aa)
	CK820_G0015962	ACACB isoform 16. (191 aa)
	ACACB	ACACB isoform 2. (2458 aa)
	SYN1	SYN1 isoform 1. (705 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2383 aa)
	CK820_G0024610	SYN3 isoform 12. (251 aa)
	GART	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
	PC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
	MCCC1	Methylcrotonoyl-CoA carboxylase 1 (Alpha). (725 aa)
	GSS	Glutathione synthetase. (474 aa)
	PCCA	Propionyl CoA carboxylase, alpha polypeptide. (728 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACACB	ENSPTRP00000074254	ENSPTRP00000079596	Acetyl-CoA carboxylase alpha.	ACACB isoform 2.	0.934
ACACA	GART	ENSPTRP00000074254	ENSPTRP00000045223	Acetyl-CoA carboxylase alpha.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.893
ACACA	MCCC1	ENSPTRP00000074254	ENSPTRP00000026948	Acetyl-CoA carboxylase alpha.	Methylcrotonoyl-CoA carboxylase 1 (Alpha).	0.619
ACACA	PC	ENSPTRP00000074254	ENSPTRP00000045149	Acetyl-CoA carboxylase alpha.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.627
ACACA	PCCA	ENSPTRP00000074254	ENSPTRP00000010202	Acetyl-CoA carboxylase alpha.	Propionyl CoA carboxylase, alpha polypeptide.	0.619
ACACB	ACACA	ENSPTRP00000079596	ENSPTRP00000074254	ACACB isoform 2.	Acetyl-CoA carboxylase alpha.	0.934
ACACB	GART	ENSPTRP00000079596	ENSPTRP00000045223	ACACB isoform 2.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.893
ACACB	MCCC1	ENSPTRP00000079596	ENSPTRP00000026948	ACACB isoform 2.	Methylcrotonoyl-CoA carboxylase 1 (Alpha).	0.609
ACACB	PC	ENSPTRP00000079596	ENSPTRP00000045149	ACACB isoform 2.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.564
ACACB	PCCA	ENSPTRP00000079596	ENSPTRP00000010202	ACACB isoform 2.	Propionyl CoA carboxylase, alpha polypeptide.	0.608
CAD	CPS1	ENSPTRP00000086335	ENSPTRP00000087073	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.902
CAD	GART	ENSPTRP00000086335	ENSPTRP00000045223	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.792
CAD	MCCC1	ENSPTRP00000086335	ENSPTRP00000026948	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Methylcrotonoyl-CoA carboxylase 1 (Alpha).	0.473
CAD	PCCA	ENSPTRP00000086335	ENSPTRP00000010202	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	Propionyl CoA carboxylase, alpha polypeptide.	0.473
CK820_G0015962	GART	ENSPTRP00000082482	ENSPTRP00000045223	ACACB isoform 16.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.893
CK820_G0015962	MCCC1	ENSPTRP00000082482	ENSPTRP00000026948	ACACB isoform 16.	Methylcrotonoyl-CoA carboxylase 1 (Alpha).	0.609
CK820_G0015962	PC	ENSPTRP00000082482	ENSPTRP00000045149	ACACB isoform 16.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.564
CK820_G0015962	PCCA	ENSPTRP00000082482	ENSPTRP00000010202	ACACB isoform 16.	Propionyl CoA carboxylase, alpha polypeptide.	0.608
CK820_G0024610	SYN2	ENSPTRP00000073111	ENSPTRP00000090775	SYN3 isoform 12.	SYN2 isoform 1.	0.571
CPS1	CAD	ENSPTRP00000087073	ENSPTRP00000086335	Carbamoyl-phosphate synthase 1, mitochondrial.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.902