STRINGSTRING
PIKFYVE PIKFYVE VPS36 VPS36 PCID2-2 PCID2-2 CUL4A CUL4A PAX9 PAX9 PLEK2 PLEK2 FOXB1 FOXB1 LARP6 LARP6 BLM BLM NSMCE1 NSMCE1 EIF3C EIF3C HSF4 HSF4 FOXF1 FOXF1 FOXL1 FOXL1 DVL2 DVL2 FOXN1 FOXN1 TADA2A TADA2A CDC6 CDC6 PSMC3IP PSMC3IP ETV4 ETV4 KAT7 KAT7 HSF5 HSF5 RGS9 RGS9 FOXJ1 FOXJ1 FOXK2 FOXK2 GTF2F1 GTF2F1 EIF3K EIF3K FOXA3 FOXA3 E2F6 E2F6 FOXN2 FOXN2 PLEK PLEK SNRNP200 SNRNP200 RFX8 RFX8 SSB SSB GPR155 GPR155 FOXO1 FOXO1 CUL3 CUL3 POLR3F POLR3F PAX1 PAX1 FOXS1 FOXS1 E2F1 E2F1 SPO11 SPO11 SMARCC1 SMARCC1 H1-10 H1-10 H1FOO H1FOO DVL3 DVL3 ETV5 ETV5 TADA2B TADA2B DEPDC1B DEPDC1B IRF1 IRF1 LARP1 LARP1 FOXI1 FOXI1 IRF4 IRF4 KDM1B KDM1B H1-1 H1-1 HIST1H1C HIST1H1C HIST1H1T HIST1H1T HIST1H1E HIST1H1E HIST1H1D HIST1H1D HIST1H1B HIST1H1B LOC104001113 LOC104001113 SPDEF SPDEF CUL7 CUL7 CUL9 CUL9 PEX14 PEX14 PAX7 PAX7 E2F2 E2F2 DEPDC1 DEPDC1 POLR3C POLR3C FOXR1 FOXR1 RFX5 RFX5 ETV3L ETV3L ELK4 ELK4 KAT6B KAT6B STN1 STN1 FOXI2 FOXI2 MGMT MGMT E2F8 E2F8 DEPDC7 DEPDC7 ELF5 ELF5 KAT5 KAT5 MUS81 MUS81 CUL5 CUL5 ASCC3 ASCC3 RFX6 RFX6 PAX4 PAX4 ZC3HAV1L ZC3HAV1L CUL1 CUL1 KAT6A KAT6A LACTB2 LACTB2 E2F5 E2F5 DEPTOR DEPTOR PLEC PLEC FOXH1 FOXH1 ANAPC2 ANAPC2 ELK1 ELK1 FOXP3 FOXP3 CUL4B CUL4B LOC473816 LOC473816 GTF2E2 GTF2E2 GTF2F2 GTF2F2 GABPA GABPA ZC3HAV1 ZC3HAV1 APAF1 APAF1 ETS2 ETS2 DDRGK1 DDRGK1 FLI1 FLI1 ERF ERF FOXK1 FOXK1 FOXE1 FOXE1 TFDP3 TFDP3 FOXB2 FOXB2 FOXD4L4 FOXD4L4 PAX5 PAX5 SHPRH SHPRH FOXO3 FOXO3 FOXF2 FOXF2 FOXN4 FOXN4 ELK3 ELK3 METAP2 METAP2 RAPGEF3 RAPGEF3 ARID2 ARID2 ETV6 ETV6 FOXJ2 FOXJ2 RPS25 RPS25 FOXQ1 FOXQ1 FOXD3 FOXD3 FOXE3 FOXE3 FOXG1 FOXG1 FOXC2 FOXC2 IRF9 IRF9 RAPGEF5 RAPGEF5 HFM1 HFM1 LARP4 LARP4 RECQL RECQL DEPDC4 DEPDC4 KAT8 KAT8 H1-0 H1-0 RAPGEF4 RAPGEF4 ELF2 ELF2 KDM1A KDM1A FOXA1 FOXA1 FOXP4 FOXP4 CUL2 CUL2 RIOK2 RIOK2 FOXN3 FOXN3 FOXC1 FOXC1 IRF3 IRF3 PAX6 PAX6 CK820_G0024573 CK820_G0024573 SPIB SPIB RPA2 RPA2 COPS4 COPS4 E2F3 E2F3 FEV FEV ETV2 ETV2 RFX1 RFX1 RGS11 RGS11 FOXD4L4-2 FOXD4L4-2 FOXP2 FOXP2 ETV3 ETV3 RGS6 RGS6 TFDP2 TFDP2 SNF8 SNF8 IRF7 IRF7 FOXD2 FOXD2 HSF2 HSF2 DVL1 DVL1 CK820_G0021068 CK820_G0021068 SETMAR SETMAR CK820_G0031740 CK820_G0031740 PREX2 PREX2 CK820_G0036339 CK820_G0036339 FOXP1 FOXP1 ERFL ERFL ETV1 ETV1 LARP4B LARP4B HP1BP3 HP1BP3 RFX4 RFX4 FOXM1 FOXM1 IRF5 IRF5 ELF3 ELF3 IRF2 IRF2 HSFX3 HSFX3 E2F4 E2F4 ERG ERG LARP7 LARP7 PSMD12 PSMD12 ELF4 ELF4 LOC453234 LOC453234 EHF EHF DEPDC5 DEPDC5 PREX1 PREX1 TFDP1 TFDP1 SMARCC2 SMARCC2 SPIC SPIC SPI1 SPI1 MYSM1 MYSM1 PAX8 PAX8 ADAR ADAR IRF8 IRF8 RFX3 RFX3 LARP1B LARP1B ETS1 ETS1 ELF1 ELF1 HSF1 HSF1 FOXO6 FOXO6 E2F7 E2F7 ZBP1 ZBP1 RFX2 RFX2 FOXI3 FOXI3 FOXJ3 FOXJ3 FOXR2 FOXR2 TIGD5 TIGD5 RPS19 RPS19 RGS7 RGS7 FOXA2 FOXA2 VPS25 VPS25 ASMT ASMT PAX3 PAX3 RFX7 RFX7 PAX2 PAX2 ETV7 ETV7 WRN WRN FOXD1 FOXD1 IRF6 IRF6 ASMTL ASMTL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
PCID2-2PCI domain-containing protein 2. (399 aa)
CUL4ACUL4A isoform 5; Belongs to the cullin family. (759 aa)
PAX9Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. (347 aa)
PLEK2PLEK2 isoform 1. (353 aa)
FOXB1FOXB1 isoform 3. (325 aa)
LARP6La ribonucleoprotein domain family, member 6. (491 aa)
BLMBLM isoform 1. (1417 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
EIF3CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (311 aa)
HSF4Heat shock transcription factor 4. (498 aa)
FOXF1FOXF1 isoform 1. (433 aa)
FOXL1FOXL1 isoform 2. (345 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
FOXN1FOXN1 isoform 2. (648 aa)
TADA2ATranscriptional adapter. (443 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
ETV4ETV4 isoform 3. (484 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
HSF5Heat shock transcription factor 5. (598 aa)
RGS9Regulator of G protein signaling 9. (674 aa)
FOXJ1FOXJ1 isoform 1. (421 aa)
FOXK2FOXK2 isoform 5. (533 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
EIF3KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
FOXA3FOXA3 isoform 2. (350 aa)
E2F6E2F transcription factor 6. (281 aa)
FOXN2FOXN2 isoform 2. (431 aa)
PLEKPLEK isoform 1. (350 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
RFX8RFX8 isoform 3. (454 aa)
SSBSmall RNA binding exonuclease protection factor La. (408 aa)
GPR155G protein-coupled receptor 155. (870 aa)
FOXO1FOXO1 isoform 1. (655 aa)
CUL3CUL3 isoform 2; Belongs to the cullin family. (768 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
PAX1PAX1 isoform 1. (457 aa)
FOXS1FOXS1 isoform 1. (330 aa)
E2F1E2F transcription factor 1. (437 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1. (1105 aa)
H1-10H1FX isoform 1. (213 aa)
H1FOOH1FOO isoform 2. (346 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
ETV5ETV5 isoform 1. (510 aa)
TADA2BTranscriptional adapter. (420 aa)
DEPDC1BDEP domain containing 1B. (529 aa)
IRF1Interferon regulatory factor. (325 aa)
LARP1La ribonucleoprotein domain family member 1. (1063 aa)
FOXI1FOXI1 isoform 2. (378 aa)
IRF4Interferon regulatory factor 4. (451 aa)
KDM1BKDM1B isoform 4. (922 aa)
H1-1HIST1H1A isoform 1. (215 aa)
HIST1H1CHIST1H1C isoform 1. (213 aa)
HIST1H1THIST1H1T isoform 1. (209 aa)
HIST1H1EHistone cluster 1 H1 family member e. (219 aa)
HIST1H1DHIST1H1D isoform 1. (221 aa)
HIST1H1BHIST1H1B isoform 1. (226 aa)
LOC104001113RPS10-NUDT3 isoform 1. (172 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
CUL7CUL7 isoform 2; Belongs to the cullin family. (1782 aa)
CUL9CUL9 isoform 1; Belongs to the cullin family. (2517 aa)
PEX14Peroxisomal biogenesis factor 14. (377 aa)
PAX7PAX7 isoform 2. (505 aa)
E2F2E2F transcription factor 2. (437 aa)
DEPDC1DEPDC1 isoform 2. (812 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
FOXR1FOXR1 isoform 1. (292 aa)
RFX5Regulatory factor X, 5 (Influences HLA class II expression). (616 aa)
ETV3LETS variant 3 like. (361 aa)
ELK4ELK4, ETS-domain protein (SRF accessory protein 1). (431 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2070 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)
FOXI2FOXI2 isoform 1. (318 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (238 aa)
E2F8E2F transcription factor 8. (867 aa)
DEPDC7DEP domain containing 7. (511 aa)
ELF5E74 like ETS transcription factor 5. (265 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
MUS81MUS81 structure-specific endonuclease subunit. (551 aa)
CUL5CUL5 isoform 1; Belongs to the cullin family. (780 aa)
ASCC3ASCC3 isoform 2. (2202 aa)
RFX6RFX6 isoform 1. (928 aa)
PAX4PAX4 isoform 1. (351 aa)
ZC3HAV1LZC3HAV1L isoform 1. (300 aa)
CUL1CUL1 isoform 1; Belongs to the cullin family. (776 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa)
LACTB2LACTB2 isoform 1. (288 aa)
E2F5E2F transcription factor 5. (345 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (409 aa)
PLECPLEC isoform 2. (4684 aa)
FOXH1FOXH1 isoform 1. (365 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
ELK1ELK1, member of ETS oncogene family. (428 aa)
FOXP3FOXP3 isoform 4. (456 aa)
CUL4BCUL4B isoform 3; Belongs to the cullin family. (932 aa)
LOC473816HSFX2 isoform 1. (423 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GABPAGA binding protein transcription factor, alpha subunit 60kDa. (454 aa)
ZC3HAV1Zinc finger CCCH-type containing, antiviral 1. (1024 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
DDRGK1DDRGK domain containing 1. (314 aa)
FLI1Fli-1 proto-oncogene, ETS transcription factor. (452 aa)
ERFEts2 repressor factor. (548 aa)
FOXK1FOXK1 isoform 1. (733 aa)
FOXE1FOXE1 isoform 1. (371 aa)
TFDP3Transcription factor. (405 aa)
FOXB2FOXB2 isoform 1. (432 aa)
FOXD4L4FOXD4L4 isoform 1. (414 aa)
PAX5PAX5 isoform 1. (391 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1683 aa)
FOXO3FOXO3 isoform 1. (673 aa)
FOXF2FOXF2 isoform 1. (444 aa)
FOXN4FOXN4 isoform 2. (517 aa)
ELK3ELK3, ETS-domain protein (SRF accessory protein 2). (407 aa)
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (477 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
ARID2AT-rich interaction domain 2. (1835 aa)
ETV6ETV6 isoform 1. (452 aa)
FOXJ2FOXJ2 isoform 1. (573 aa)
RPS2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
FOXQ1FOXQ1 isoform 1. (403 aa)
FOXD3FOXD3 isoform 1. (478 aa)
FOXE3FOXE3 isoform 1. (319 aa)
FOXG1FOXG1 isoform 8. (489 aa)
FOXC2Forkhead box C2 (MFH-1, mesenchyme forkhead 1). (501 aa)
IRF9Interferon regulatory factor 9. (391 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
HFM1HFM1 isoform 1. (1435 aa)
LARP4La ribonucleoprotein domain family, member 4. (724 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (778 aa)
DEPDC4DEPDC4 isoform 3. (293 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
H1-0H1F0 isoform 1. (194 aa)
RAPGEF4RAPGEF4 isoform 2. (1011 aa)
ELF2E74 like ETS transcription factor 2. (593 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
FOXA1FOXA1 isoform 1. (471 aa)
FOXP4FOXP4 isoform 3. (668 aa)
CUL2CUL2 isoform 8; Belongs to the cullin family. (764 aa)
RIOK2RIOK2 isoform 1. (552 aa)
FOXN3FOXN3 isoform 2. (490 aa)
FOXC1FOXC1 isoform 1. (550 aa)
IRF3Interferon regulatory factor 3. (452 aa)
PAX6PAX6 isoform 13. (436 aa)
CK820_G0024573DEPDC5 isoform 16. (1595 aa)
SPIBT0182711 isoform 1. (1107 aa)
RPA2Replication protein A2, 32kDa. (282 aa)
COPS4COP9 constitutive photomorphogenic homolog subunit 4. (437 aa)
E2F3E2F transcription factor 3. (465 aa)
FEVFEV transcription factor, ETS family member. (238 aa)
ETV2ETV2 isoform 5. (370 aa)
RFX1Regulatory factor X1. (983 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
FOXD4L4-2FOXD4L6 isoform 1. (335 aa)
FOXP2Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (741 aa)
ETV3ETS translocation variant 3; Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity (By similarity); Belongs to the ETS family. (512 aa)
RGS6RGS6 isoform 14. (538 aa)
TFDP2Transcription factor. (447 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
IRF7Interferon regulatory factor 7. (516 aa)
FOXD2FOXD2 isoform 1. (493 aa)
HSF2Heat shock transcription factor 2. (536 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1; Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By simi [...] (743 aa)
CK820_G0021068Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (341 aa)
SETMARSET domain and mariner transposase fusion gene. (684 aa)
CK820_G0031740IRF2 isoform 7. (122 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1620 aa)
CK820_G0036339TFDP1 isoform 5. (370 aa)
FOXP1FOXP1 isoform 2. (693 aa)
ERFLETS repressor factor like. (354 aa)
ETV1ETV1 isoform 11. (511 aa)
LARP4BLa ribonucleoprotein domain family, member 4B. (753 aa)
HP1BP3Heterochromatin protein 1, binding protein 3. (553 aa)
RFX4Regulatory factor X4. (744 aa)
FOXM1FOXM1 isoform 4. (787 aa)
IRF5Interferon regulatory factor 5. (515 aa)
ELF3E74 like ETS transcription factor 3. (375 aa)
IRF2Interferon regulatory factor. (349 aa)
HSFX3HSFX3 isoform 1. (333 aa)
E2F4E2F transcription factor 4, p107/p130-binding. (414 aa)
ERGV-ets erythroblastosis virus E26 oncogene homolog (Avian). (486 aa)
LARP7La ribonucleoprotein domain family member 7. (589 aa)
PSMD12Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12. (480 aa)
ELF4E74-like factor 4 (Ets domain transcription factor). (663 aa)
LOC453234T0192978 isoform 1. (233 aa)
EHFETS homologous factor; Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter (By similarity). (322 aa)
DEPDC5DEP domain containing 5. (1605 aa)
PREX1Phosphatidylinositol-3,4, 5-trisphosphate-dependent Rac exchange factor 1. (1659 aa)
TFDP1Transcription factor. (352 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa)
SPICSpi-C transcription factor. (250 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
MYSM1Myb-like, SWIRM and MPN domains 1. (828 aa)
PAX8PAX8 isoform 1. (456 aa)
ADARAdenosine deaminase, RNA-specific. (1229 aa)
IRF8Interferon regulatory factor 8. (426 aa)
RFX3RFX3 isoform 4. (761 aa)
LARP1BLa ribonucleoprotein domain family, member 1B. (914 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
ELF1E74-like factor 1 (Ets domain transcription factor). (619 aa)
HSF1Heat shock transcription factor 1. (529 aa)
FOXO6FOXO6 isoform 2. (559 aa)
E2F7E2F transcription factor 7. (911 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
RFX2Regulatory factor X2. (725 aa)
FOXI3FOXI3 isoform 1. (411 aa)
FOXJ3FOXJ3 isoform 1. (622 aa)
FOXR2FOXR2 isoform 1. (311 aa)
TIGD5Tigger transposable element derived 5. (643 aa)
RPS19Ribosomal protein S19. (145 aa)
RGS7Regulator of G-protein signaling 7. (487 aa)
FOXA2FOXA2 isoform 1. (464 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
ASMTAcetylserotonin O-methyltransferase. (373 aa)
PAX3PAX3 isoform 4. (505 aa)
RFX7Regulatory factor X, 7. (1403 aa)
PAX2PAX2 isoform 1. (417 aa)
ETV7ETV7 isoform 4. (362 aa)
WRNWRN RecQ like helicase. (1446 aa)
FOXD1FOXD1 isoform 1. (439 aa)
IRF6Interferon regulatory factor 6. (467 aa)
ASMTLASMTL isoform 3. (588 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (14%) [HD]