(18 nodes) MPN domain network (Pan troglodytes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BRCC3	BRCA1/BRCA2-containing complex subunit 3. (317 aa)
	MYSM1	Myb-like, SWIRM and MPN domains 1. (828 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa)
	PSMD14	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14. (310 aa)
	COPS6	COP9 constitutive photomorphogenic homolog subunit 6. (327 aa)
	COPS5	COP9 constitutive photomorphogenic homolog subunit 5. (334 aa)
	ABRAXAS2	Family with sequence similarity 175, member B. (415 aa)
	ABRAXAS1	Family with sequence similarity 175, member A. (409 aa)
	PRPF8	PRP8 pre-mRNA processing factor 8 homolog. (2335 aa)
	CK820_G0003646	ABRAXAS1 isoform 9. (311 aa)
	STAMBPL1	STAM binding protein like 1. (461 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (608 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa)
	MPND	MPN domain containing. (501 aa)
	EMC9	Family with sequence similarity 158, member A. (208 aa)
	PSMD7	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7. (324 aa)
	EMC8	ER membrane protein complex subunit 8. (210 aa)
	STAMBP	STAM binding protein. (424 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABRAXAS1	BRCC3	ENSPTRP00000053580	ENSPTRP00000072574	Family with sequence similarity 175, member A.	BRCA1/BRCA2-containing complex subunit 3.	0.986
ABRAXAS1	COPS5	ENSPTRP00000053580	ENSPTRP00000043693	Family with sequence similarity 175, member A.	COP9 constitutive photomorphogenic homolog subunit 5.	0.526
ABRAXAS1	COPS6	ENSPTRP00000053580	ENSPTRP00000033321	Family with sequence similarity 175, member A.	COP9 constitutive photomorphogenic homolog subunit 6.	0.526
ABRAXAS1	EIF3F	ENSPTRP00000053580	ENSPTRP00000005810	Family with sequence similarity 175, member A.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.526
ABRAXAS1	MPND	ENSPTRP00000053580	ENSPTRP00000075711	Family with sequence similarity 175, member A.	MPN domain containing.	0.691
ABRAXAS1	MYSM1	ENSPTRP00000053580	ENSPTRP00000084507	Family with sequence similarity 175, member A.	Myb-like, SWIRM and MPN domains 1.	0.691
ABRAXAS1	PSMD14	ENSPTRP00000053580	ENSPTRP00000021491	Family with sequence similarity 175, member A.	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14.	0.691
ABRAXAS1	PSMD7	ENSPTRP00000053580	ENSPTRP00000014246	Family with sequence similarity 175, member A.	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7.	0.526
ABRAXAS1	STAMBP	ENSPTRP00000053580	ENSPTRP00000020712	Family with sequence similarity 175, member A.	STAM binding protein.	0.526
ABRAXAS1	STAMBPL1	ENSPTRP00000053580	ENSPTRP00000063854	Family with sequence similarity 175, member A.	STAM binding protein like 1.	0.526
ABRAXAS2	BRCC3	ENSPTRP00000045616	ENSPTRP00000072574	Family with sequence similarity 175, member B.	BRCA1/BRCA2-containing complex subunit 3.	0.986
ABRAXAS2	PSMD14	ENSPTRP00000045616	ENSPTRP00000021491	Family with sequence similarity 175, member B.	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14.	0.535
ABRAXAS2	PSMD7	ENSPTRP00000045616	ENSPTRP00000014246	Family with sequence similarity 175, member B.	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7.	0.453
BRCC3	ABRAXAS1	ENSPTRP00000072574	ENSPTRP00000053580	BRCA1/BRCA2-containing complex subunit 3.	Family with sequence similarity 175, member A.	0.986
BRCC3	ABRAXAS2	ENSPTRP00000072574	ENSPTRP00000045616	BRCA1/BRCA2-containing complex subunit 3.	Family with sequence similarity 175, member B.	0.986
BRCC3	CK820_G0003646	ENSPTRP00000072574	ENSPTRP00000061481	BRCA1/BRCA2-containing complex subunit 3.	ABRAXAS1 isoform 9.	0.960
BRCC3	EIF3H	ENSPTRP00000072574	ENSPTRP00000070225	BRCA1/BRCA2-containing complex subunit 3.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	0.745
BRCC3	MYSM1	ENSPTRP00000072574	ENSPTRP00000084507	BRCA1/BRCA2-containing complex subunit 3.	Myb-like, SWIRM and MPN domains 1.	0.401
BRCC3	PSMD7	ENSPTRP00000072574	ENSPTRP00000014246	BRCA1/BRCA2-containing complex subunit 3.	Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7.	0.876
CK820_G0003646	BRCC3	ENSPTRP00000061481	ENSPTRP00000072574	ABRAXAS1 isoform 9.	BRCA1/BRCA2-containing complex subunit 3.	0.960