STRINGSTRING
FNDC3B FNDC3B LCK LCK NRAS NRAS HRAS HRAS CBL CBL KITLG KITLG SH2B3 SH2B3 CMA1 CMA1 FES FES SOCS1 SOCS1 STAT5A STAT5A PRKCA PRKCA GRB2 GRB2 SOCS6 SOCS6 JAK2 JAK2 ENSPTRP00000081537 ENSPTRP00000081537 FYN FYN ENSPTRP00000077211 ENSPTRP00000077211 PIK3R1 PIK3R1 SRC SRC GRAPL GRAPL CK820_G0050194 CK820_G0050194 ENSPTRP00000074763 ENSPTRP00000074763 SH2B2 SH2B2 PTPN11-2 PTPN11-2 TEC TEC PTPRU PTPRU GRB7 GRB7 CSDE1 CSDE1 RAC1 RAC1 TEC-2 TEC-2 CHEK1 CHEK1 ENSPTRP00000067174 ENSPTRP00000067174 ERAS ERAS PIK3R3 PIK3R3 ENSPTRP00000062007 ENSPTRP00000062007 PTPN11 PTPN11 GRB10 GRB10 GAB4 GAB4 SOS1 SOS1 PTPN6 PTPN6 ELSPBP1 ELSPBP1 LYN LYN GAB2 GAB2 FER FER KIT KIT GRAP2 GRAP2 MMP9 MMP9 PIK3R2 PIK3R2 PIK3CA PIK3CA KRAS KRAS RAC1-2 RAC1-2 FNDC3A FNDC3A ENSPTRP00000083456 ENSPTRP00000083456 ENSPTRP00000085461 ENSPTRP00000085461 VAV1 VAV1 STAT5B STAT5B YES1 YES1 STAT1 STAT1 ENSPTRP00000091157 ENSPTRP00000091157 STAT3 STAT3 ENSPTRP00000092364 ENSPTRP00000092364
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
LCKTyrosine-protein kinase. (539 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
CBLCas-Br-M (Murine) ecotropic retroviral transforming sequence. (906 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
SH2B3SH2B adaptor protein 3. (575 aa)
CMA1CMA1 isoform 1; Belongs to the peptidase S1 family. (252 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
STAT5ASignal transducer and activator of transcription. (783 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
JAK2Tyrosine-protein kinase. (1143 aa)
ENSPTRP00000081537annotation not available (449 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSPTRP00000077211annotation not available (269 aa)
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa)
SRCTyrosine-protein kinase. (542 aa)
GRAPLGRAP isoform 4. (100 aa)
CK820_G0050194GRAP isoform 1. (153 aa)
ENSPTRP00000074763annotation not available (520 aa)
SH2B2Uncharacterized protein. (677 aa)
PTPN11-2Protein tyrosine phosphatase non-receptor type 11. (579 aa)
TECTyrosine-protein kinase. (631 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1454 aa)
GRB7Growth factor receptor bound protein 7. (555 aa)
CSDE1Cold shock domain containing E1. (844 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
TEC-2Tec protein tyrosine kinase. (51 aa)
CHEK1CHEK1 isoform 10. (485 aa)
ENSPTRP00000067174annotation not available (502 aa)
ERASES cell expressed Ras. (233 aa)
PIK3R3Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma). (478 aa)
ENSPTRP00000062007SH2B adapter protein 2-like. (570 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
GRB10Growth factor receptor-bound protein 10. (594 aa)
GAB4GAB4 isoform 1. (685 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ELSPBP1ELSPBP1 isoform 6. (219 aa)
LYNTyrosine-protein kinase. (512 aa)
GAB2GRB2-associated-binding protein 2. (676 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
MMP9Matrix metallopeptidase 9. (699 aa)
PIK3R2Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSPTRP00000083456annotation not available (649 aa)
ENSPTRP00000085461annotation not available (478 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
STAT5BSignal transducer and activator of transcription. (772 aa)
YES1Tyrosine-protein kinase. (558 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
ENSPTRP00000091157annotation not available (617 aa)
STAT3Signal transducer and activator of transcription. (790 aa)
ENSPTRP00000092364annotation not available (574 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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