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ENSPTRP00000074059 | annotation not available (180 aa) | ||||
RALB | V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein). (212 aa) | ||||
DNM2 | DNM2 isoform 5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) | ||||
PTPN11-2 | Protein tyrosine phosphatase non-receptor type 11. (579 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
ENSPTRP00000070794 | annotation not available (426 aa) | ||||
MEF2A | Myocyte enhancer factor 2A. (507 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) | ||||
ENSPTRP00000069037 | annotation not available (328 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) | ||||
AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa) | ||||
ENSPTRP00000067174 | annotation not available (502 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) | ||||
LOC736439 | AP-2 complex subunit beta pseudogene. (893 aa) | ||||
ENSPTRP00000065064 | annotation not available (405 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
SHC3 | SHC3 isoform 2. (598 aa) | ||||
PPP2CA | PPP2CB isoform 8. (309 aa) | ||||
RPS6KA2 | Ribosomal protein S6 kinase alpha-2 isoform X1. (758 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa) | ||||
CK820_G0014320 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (88 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa) | ||||
ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (155 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (370 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
ARC | Activity-regulated cytoskeleton-associated protein. (396 aa) | ||||
MAPK15 | Mitogen-activated protein kinase. (544 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1. (584 aa) | ||||
PPP4R1 | Protein phosphatase 4, regulatory subunit 1. (950 aa) | ||||
PCSK4 | PCSK4 isoform 5; Belongs to the peptidase S8 family. (708 aa) | ||||
JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) | ||||
CRKL | V-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa) | ||||
PCSK6 | PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa) | ||||
DNM3 | DNM3 isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa) | ||||
NELFB | NELFB isoform 1. (730 aa) | ||||
AP2B1 | AP complex subunit beta. (951 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) | ||||
REST | RE1 silencing transcription factor. (1097 aa) | ||||
ELK1 | ELK1, member of ETS oncogene family. (428 aa) | ||||
RALGDS | Ral guanine nucleotide dissociation stimulator. (914 aa) | ||||
PCSK5 | PCSK5 isoform 1; Belongs to the peptidase S8 family. (1860 aa) | ||||
CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (372 aa) | ||||
DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
RALA | V-ral simian leukemia viral oncogene homolog A (Ras related). (206 aa) | ||||
SRF | Serum response factor (C-fos serum response element-binding transcription factor). (508 aa) | ||||
PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) | ||||
FRS3 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) | ||||
ENSPTRP00000029492 | annotation not available (223 aa) | ||||
GAB1 | GRB2-associated-binding protein 1. (724 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) | ||||
DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) | ||||
MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
EP300 | E1A binding protein p300. (2175 aa) | ||||
DNAL4 | Dynein light chain. (105 aa) | ||||
ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
TIAM1 | T-cell lymphoma invasion and metastasis 1. (1591 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1). (487 aa) | ||||
EGR4 | Early growth response 4. (589 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1771 aa) | ||||
ID2 | Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa) | ||||
VRK3 | VRK serine/threonine kinase 3. (474 aa) | ||||
NTF4 | NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa) | ||||
NKPD1 | NTPase KAP family P-loop domain containing 1. (612 aa) | ||||
PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) | ||||
PTPRS | Protein tyrosine phosphatase receptor type S. (1948 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2. (217 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) | ||||
FURIN | Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family. (794 aa) | ||||
SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (355 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
TCF12 | Transcription factor 12. (706 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
IRS2 | IRS2 isoform 1. (1340 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2). (525 aa) | ||||
ATF1 | Activating transcription factor 1. (270 aa) | ||||
GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) | ||||
PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) | ||||
FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) | ||||
FNBP4 | Formin binding protein 4. (1019 aa) | ||||
AP2A2 | AP2A2 isoform 4. (380 aa) | ||||
HRAS | V-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
MAPKAPK2 | Mitogen-activated protein kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
RIT1 | Ras like without CAAX 1. (236 aa) | ||||
NRAS | Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa) | ||||
ID3 | Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein. (119 aa) | ||||
CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa) | ||||
RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) | ||||
ENSPTRP00000092364 | annotation not available (574 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (790 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
CREM | cAMP responsive element modulator. (345 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
PPP4R4 | Protein phosphatase 4, regulatory subunit 4. (873 aa) | ||||
ENSPTRP00000090382 | annotation not available (493 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) | ||||
DOCK3 | Dedicator of cytokinesis 3; Belongs to the DOCK family. (2030 aa) | ||||
ENSPTRP00000089450 | annotation not available (303 aa) | ||||
BRAF-2 | BRAF isoform 2. (766 aa) | ||||
AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
CDK5R2 | Cyclin-dependent kinase 5 activator. (367 aa) | ||||
DNM1-2 | Dynamin 1. (867 aa) | ||||
LOC100612020 | Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1. (954 aa) | ||||
FOSB | FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa) | ||||
NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa) | ||||
ID1-2 | Inhibitor of DNA binding 1, HLH protein. (155 aa) | ||||
SGK1 | Non-specific serine/threonine protein kinase. (526 aa) | ||||
ENSPTRP00000085189 | annotation not available (1896 aa) | ||||
FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa) | ||||
RAC1-2 | Rac family small GTPase 1. (212 aa) | ||||
DNM1 | DNM1 isoform 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa) | ||||
ENSPTRP00000084126 | annotation not available (117 aa) | ||||
FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) | ||||
CHD4 | Chromodomain helicase DNA binding protein 4. (1912 aa) | ||||
PPP2R1A | Protein phosphatase 2, regulatory subunit A, alpha. (637 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) | ||||
MAPK13 | Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] (366 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) | ||||
SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (352 aa) | ||||
ASCL2 | Achaete-scute family bHLH transcription factor 2. (193 aa) | ||||
FRS3-2 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa) | ||||
BRAF | BRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) | ||||
TPH1 | Tryptophan hydroxylase 1. (444 aa) | ||||
AP2M1 | AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family. (459 aa) | ||||
ASCL1 | Achaete-scute family bHLH transcription factor 1. (232 aa) | ||||
JUND | JUND isoform 1. (346 aa) | ||||
ADCYAP1R1-2 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (517 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
ENSPTRP00000077211 | annotation not available (269 aa) | ||||
ENSPTRP00000076988 | annotation not available (871 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
ENSPTRP00000076429 | annotation not available (110 aa) | ||||
RIT2 | Ras like without CAAX 2. (217 aa) | ||||
ENSPTRP00000074910 | annotation not available (405 aa) | ||||
ENSPTRP00000074763 | annotation not available (520 aa) | ||||
LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) | ||||
RAPGEF1 | RAPGEF1 isoform 5. (1065 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) | ||||
MEF2D | Myocyte enhancer factor 2D. (521 aa) |