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ID3 | Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein. (119 aa) | ||||
NRAS | Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa) | ||||
RIT1 | Ras like without CAAX 1. (236 aa) | ||||
MAPKAPK2 | Mitogen-activated protein kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
HRAS | V-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa) | ||||
AP2A2 | AP2A2 isoform 4. (380 aa) | ||||
FNBP4 | Formin binding protein 4. (1019 aa) | ||||
FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) | ||||
PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) | ||||
GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) | ||||
ATF1 | Activating transcription factor 1. (270 aa) | ||||
NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2). (525 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
IRS2 | IRS2 isoform 1. (1340 aa) | ||||
SHC4 | SHC adaptor protein 4. (630 aa) | ||||
TCF12 | Transcription factor 12. (706 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (355 aa) | ||||
FURIN | Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family. (794 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2. (217 aa) | ||||
ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
PTPRS | Protein tyrosine phosphatase receptor type S. (1948 aa) | ||||
PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) | ||||
NKPD1 | NTPase KAP family P-loop domain containing 1. (612 aa) | ||||
NTF4 | NTF4 isoform 1; Belongs to the NGF-beta family. (210 aa) | ||||
VRK3 | VRK serine/threonine kinase 3. (474 aa) | ||||
ID2 | Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein. (134 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1771 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
EGR4 | Early growth response 4. (589 aa) | ||||
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1). (487 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1241 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) | ||||
TIAM1 | T-cell lymphoma invasion and metastasis 1. (1591 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa) | ||||
DNAL4 | Dynein light chain. (105 aa) | ||||
EP300 | E1A binding protein p300. (2175 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) | ||||
DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) | ||||
GAB1 | GRB2-associated-binding protein 1. (724 aa) | ||||
ENSPTRP00000029492 | annotation not available (223 aa) | ||||
MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) | ||||
FRS3 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) | ||||
SRF | Serum response factor (C-fos serum response element-binding transcription factor). (508 aa) | ||||
RALA | V-ral simian leukemia viral oncogene homolog A (Ras related). (206 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (372 aa) | ||||
CLTA | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa) | ||||
PCSK5 | PCSK5 isoform 1; Belongs to the peptidase S8 family. (1860 aa) | ||||
RALGDS | Ral guanine nucleotide dissociation stimulator. (914 aa) | ||||
ELK1 | ELK1, member of ETS oncogene family. (428 aa) | ||||
REST | RE1 silencing transcription factor. (1097 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (295 aa) | ||||
AP2B1 | AP complex subunit beta. (951 aa) | ||||
NELFB | NELFB isoform 1. (730 aa) | ||||
DNM3 | DNM3 isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa) | ||||
PCSK6 | PCSK6 isoform 3; Belongs to the peptidase S8 family. (968 aa) | ||||
CRKL | V-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (303 aa) | ||||
JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) | ||||
PCSK4 | PCSK4 isoform 5; Belongs to the peptidase S8 family. (708 aa) | ||||
PPP4R1 | Protein phosphatase 4, regulatory subunit 1. (950 aa) | ||||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1. (584 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) | ||||
MAPK15 | Mitogen-activated protein kinase. (544 aa) | ||||
ARC | Activity-regulated cytoskeleton-associated protein. (396 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (370 aa) | ||||
ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (155 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) | ||||
CK820_G0014320 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (88 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (393 aa) | ||||
RPS6KA2 | Ribosomal protein S6 kinase alpha-2 isoform X1. (758 aa) | ||||
PPP2CA | PPP2CB isoform 8. (309 aa) | ||||
SHC3 | SHC3 isoform 2. (598 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
ERAS | ES cell expressed Ras. (233 aa) | ||||
ENSPTRP00000065064 | annotation not available (405 aa) | ||||
LOC736439 | AP-2 complex subunit beta pseudogene. (893 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) | ||||
ENSPTRP00000067174 | annotation not available (502 aa) | ||||
AP2A1 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) | ||||
ENSPTRP00000069037 | annotation not available (328 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (123 aa) | ||||
MEF2A | Myocyte enhancer factor 2A. (507 aa) | ||||
ENSPTRP00000070794 | annotation not available (426 aa) | ||||
CSDE1 | Cold shock domain containing E1. (844 aa) | ||||
ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein. (161 aa) | ||||
CREB1 | cAMP responsive element binding protein 1. (341 aa) | ||||
PTPN11-2 | Protein tyrosine phosphatase non-receptor type 11. (579 aa) | ||||
DNM2 | DNM2 isoform 5; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) | ||||
RALB | V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein). (212 aa) | ||||
ENSPTRP00000074059 | annotation not available (180 aa) | ||||
MEF2D | Myocyte enhancer factor 2D. (521 aa) | ||||
ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
RAPGEF1 | RAPGEF1 isoform 5. (1065 aa) | ||||
LYL1 | LYL1 basic helix-loop-helix family member. (280 aa) | ||||
ENSPTRP00000074763 | annotation not available (520 aa) | ||||
ENSPTRP00000074910 | annotation not available (405 aa) | ||||
RIT2 | Ras like without CAAX 2. (217 aa) | ||||
ENSPTRP00000076429 | annotation not available (110 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) | ||||
ENSPTRP00000076988 | annotation not available (871 aa) | ||||
ENSPTRP00000077211 | annotation not available (269 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
ADCYAP1R1-2 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (517 aa) | ||||
JUND | JUND isoform 1. (346 aa) | ||||
ASCL1 | Achaete-scute family bHLH transcription factor 1. (232 aa) | ||||
AP2M1 | AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family. (459 aa) | ||||
TPH1 | Tryptophan hydroxylase 1. (444 aa) | ||||
PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
BRAF | BRAF isoform 1; Belongs to the protein kinase superfamily. (767 aa) | ||||
CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa) | ||||
FRS3-2 | Fibroblast growth factor receptor substrate 3. (492 aa) | ||||
ASCL2 | Achaete-scute family bHLH transcription factor 2. (193 aa) | ||||
SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (352 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) | ||||
MAPK13 | Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] (366 aa) | ||||
CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (796 aa) | ||||
PPP2R1A | Protein phosphatase 2, regulatory subunit A, alpha. (637 aa) | ||||
CHD4 | Chromodomain helicase DNA binding protein 4. (1912 aa) | ||||
FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) | ||||
ENSPTRP00000084126 | annotation not available (117 aa) | ||||
DNM1 | DNM1 isoform 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa) | ||||
RAC1-2 | Rac family small GTPase 1. (212 aa) | ||||
KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) | ||||
FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) | ||||
ENSPTRP00000085189 | annotation not available (1896 aa) | ||||
SGK1 | Non-specific serine/threonine protein kinase. (526 aa) | ||||
ID1-2 | Inhibitor of DNA binding 1, HLH protein. (155 aa) | ||||
NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. (864 aa) | ||||
FOSB | FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa) | ||||
LOC100612020 | Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1. (954 aa) | ||||
DNM1-2 | Dynamin 1. (867 aa) | ||||
CDK5R2 | Cyclin-dependent kinase 5 activator. (367 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
AP2S1 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa) | ||||
BRAF-2 | BRAF isoform 2. (766 aa) | ||||
ENSPTRP00000089450 | annotation not available (303 aa) | ||||
DOCK3 | Dedicator of cytokinesis 3; Belongs to the DOCK family. (2030 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (275 aa) | ||||
FRS2 | Fibroblast growth factor receptor substrate 2. (521 aa) | ||||
ENSPTRP00000090382 | annotation not available (493 aa) | ||||
PPP4R4 | Protein phosphatase 4, regulatory subunit 4. (873 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
CREM | cAMP responsive element modulator. (345 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (790 aa) | ||||
ENSPTRP00000092364 | annotation not available (574 aa) | ||||
RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) | ||||
CLTC | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa) |