Your Input: | |
| | SHF | Src homology 2 domain containing F. (423 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | ENSPTRP00000076371 | annotation not available (194 aa) |
| | ENSPTRP00000075918 | annotation not available (365 aa) |
| | PXN-2 | PXN isoform 9. (1081 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | NCF4 | Neutrophil cytosolic factor 4. (368 aa) |
| | ABI2 | Abl interactor 2. (513 aa) |
| | ELMO1 | Engulfment and cell motility 1. (769 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | PXN | PXN isoform 20. (1078 aa) |
| | HSP90AA1 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (855 aa) |
| | ENSPTRP00000070878 | annotation not available (324 aa) |
| | MLST8 | MLST8 isoform 3. (327 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa) |
| | ITGB3 | Integrin beta-3 isoform X2. (837 aa) |
| | ENSPTRP00000066583 | annotation not available (181 aa) |
| | AHCYL1 | Adenosylhomocysteinase. (499 aa) |
| | ENSPTRP00000065141 | annotation not available (119 aa) |
| | BAIAP2 | BAI1 associated protein 2. (553 aa) |
| | ENSPTRP00000064849 | annotation not available (150 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | PAK3 | Serine/threonine-protein kinase PAK 3; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstrea [...] (580 aa) |
| | ACTL9 | ACTL9 isoform 1; Belongs to the actin family. (416 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (221 aa) |
| | ARVCF | ARVCF isoform 1. (962 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa) |
| | ELMO3 | Engulfment and cell motility 3. (773 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (370 aa) |
| | SPHK1 | Sphingosine kinase 1. (470 aa) |
| | SH2D2A | SH2D2A isoform 1. (361 aa) |
| | SHB | Src homology 2 domain containing adaptor protein B. (509 aa) |
| | ITGAV | Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | LOC744297 | POTE ankyrin domain family member G-like. (956 aa) |
| | WASF1 | Wiskott-Aldrich syndrome protein family member 1. (559 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | CTNNB1 | Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | WASF3 | WH2 domain-containing protein. (502 aa) |
| | ACTRT1 | Actin related protein T1; Belongs to the actin family. (376 aa) |
| | TENM1 | Teneurin transmembrane protein 1. (2732 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | MAPKAP1 | Mitogen-activated protein kinase associated protein 1. (522 aa) |
| | ACTL7A | Actin-like protein 7A; Belongs to the actin family. (435 aa) |
| | ACTL7B | Actin-like protein 7B; Belongs to the actin family. (415 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa) |
| | CK820_G0053598 | POTEJ isoform 1; Belongs to the actin family. (1078 aa) |
| | PTK2B | PTK2B protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (390 aa) |
| | STX7 | STX7 isoform 4; Belongs to the syntaxin family. (261 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) |
| | ITPR3 | ITPR3 isoform 1. (2677 aa) |
| | TENM2 | Teneurin transmembrane protein 2. (2774 aa) |
| | CTNNA1 | CTNNA1 isoform 21. (906 aa) |
| | RASA1 | RAS p21 protein activator (GTPase activating protein) 1. (1047 aa) |
| | TENM3 | Teneurin transmembrane protein 3. (2699 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (476 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | BRK1 | BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa) |
| | ITPR1 | ITPR1 isoform 3. (2700 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa) |
| | PRR5 | Proline-rich protein 5 isoform X2. (411 aa) |
| | ELMO2 | Engulfment and cell motility 2. (732 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | TRIB3 | TRIB3 isoform 4. (386 aa) |
| | AAMP | Angio associated migratory cell protein. (435 aa) |
| | NRP2 | Neuropilin; Belongs to the neuropilin family. (931 aa) |
| | NCKAP1 | Nck-associated protein 1. (1128 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | CALM3 | Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa) |
| | PIK3R2 | Phosphoinositide-3-kinase, regulatory subunit 2 (Beta). (728 aa) |
| | HSH2D | HSH2D isoform 1. (352 aa) |
| | PRKACA | PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | SHD | Src homology 2 domain containing transforming protein D. (340 aa) |
| | ENSPTRP00000016618 | Actin beta like 2. (375 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | RNF222 | Ring finger protein 222. (220 aa) |
| | CDH5 | CDH5 isoform 1; Cadherins are calcium-dependent cell adhesion proteins. (784 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | EFS | Embryonal Fyn-associated substrate. (560 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1127 aa) |
| | TENM4 | Teneurin transmembrane protein 4. (2769 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (553 aa) |
| | HRAS | V-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa) |
| | DOCK1 | DOCK1 isoform 1; Belongs to the DOCK family. (1854 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | MAPKAPK2 | Mitogen-activated protein kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | NCF2 | Neutrophil cytosolic factor 2. (526 aa) |
| | SHE | Src homology 2 domain containing E. (495 aa) |
| | THEM4 | Thioesterase superfamily member 4. (240 aa) |
| | NRAS | Neuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa) |
| | STX12 | STX12 isoform 1; Belongs to the syntaxin family. (276 aa) |
| | ENSPTRP00000000715 | Wiskott-Aldrich syndrome protein family member 2-like. (492 aa) |
| | WASF2 | WAS protein family, member 2. (498 aa) |
| | ACTL8 | ACTL8 isoform 1; Belongs to the actin family. (366 aa) |
| | SZRD1 | SUZ RNA binding domain containing 1. (152 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | ACTRT2 | ACTRT2 isoform 1; Belongs to the actin family. (377 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase, regulatory subunit 1 (Alpha). (724 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | CDC42 | Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa) |
| | CK820_G0023066 | ACTA1 isoform 2. (150 aa) |
| | CK820_G0040570 | PRKCZ isoform 2. (457 aa) |
| | ENSPTRP00000079105 | annotation not available (149 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | ACTG1 | ACTG1 isoform 13. (375 aa) |
| | ENSPTRP00000080740 | annotation not available (150 aa) |
| | ENSPTRP00000081694 | annotation not available (182 aa) |
| | ENSPTRP00000081707 | annotation not available (149 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | MAPK13 | Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] (366 aa) |
| | CRK | V-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | RAC1-2 | Rac family small GTPase 1. (212 aa) |
| | KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress (By simi [...] (1368 aa) |
| | ENSPTRP00000084892 | annotation not available (374 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CTNND1 | CTNND1 isoform 23. (975 aa) |
| | AXL | AXL receptor tyrosine kinase. (894 aa) |
| | CASS4 | CASS4 isoform 2. (812 aa) |
| | CK820_G0040570-2 | PRKCZ isoform 4. (95 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | VAV3 | VAV3 isoform 2. (927 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase-1. (542 aa) |
| | CYBA | Cytochrome b-245 alpha chain. (210 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (839 aa) |
| | ENSPTRP00000093517 | annotation not available (149 aa) |
