STRINGSTRING
TERT TERT LOC471907 LOC471907 LOC107971253 LOC107971253 H2AJ H2AJ RBBP5 RBBP5 H2BC21 H2BC21 RUVBL1 RUVBL1 HIST1H2AE HIST1H2AE H2BC13 H2BC13 LOC471883 LOC471883 TLE4 TLE4 H2BC5 H2BC5 SMARCA4 SMARCA4 ENSPTRP00000074115 ENSPTRP00000074115 LOC112209457-4 LOC112209457-4 LOC471883-2 LOC471883-2 LOC107971249-2 LOC107971249-2 CREBBP CREBBP MYC MYC LOC746430 LOC746430 HDAC1 HDAC1 H4C8 H4C8 LOC457262-5 LOC457262-5 ENSPTRP00000078054 ENSPTRP00000078054 CK820_G0051198 CK820_G0051198 LOC112209457-5 LOC112209457-5 LOC107966300 LOC107966300 LOC457262-6 LOC457262-6 LEF1 LEF1 TCF7 TCF7 TCF7L2 TCF7L2 LOC457262-7 LOC457262-7 ENSPTRP00000084305 ENSPTRP00000084305 CK820_G0031483 CK820_G0031483 LOC457262-8 LOC457262-8 PYGO1 PYGO1 H2BC14 H2BC14 H3F3B H3F3B LOC462509 LOC462509 LOC457262-9 LOC457262-9 TRRAP TRRAP TLE2 TLE2 TLE1 TLE1 CTNNB1 CTNNB1 KMT2D KMT2D LOC107971249 LOC107971249 H2AFV H2AFV H2AC14 H2AC14 H2BC11 H2BC11 LOC112209457 LOC112209457 H2AC6 H2AC6 LOC462501 LOC462501 LOC457262-2 LOC457262-2 HIST1H2BB HIST1H2BB LOC748495 LOC748495 HIST1H2BA HIST1H2BA TERT-2 TERT-2 H2BC9 H2BC9 H2AZ1 H2AZ1 EP300 EP300 HIST1H3A HIST1H3A TCF7L1 TCF7L1 TLE6 TLE6 AXIN2 AXIN2 TLE3 TLE3 LEO1 LEO1 H2AC7 H2AC7 LOC457262 LOC457262 H2AFX H2AFX BCL9L BCL9L KAT5 KAT5 MEN1 MEN1 LOC469702 LOC469702 PYGO2 PYGO2 H3-4 H3-4 BCL9 BCL9 RUNX3 RUNX3 H2BU1 H2BU1 CDC73 CDC73 LOC457262-10 LOC457262-10 ENSPTRP00000090987 ENSPTRP00000090987 H2BC6 H2BC6 LOC471875 LOC471875 H2AC20 H2AC20 ENSPTRP00000092628 ENSPTRP00000092628 LOC112209457-6 LOC112209457-6 H3C13 H3C13 LOC104001083 LOC104001083 LOC471880 LOC471880 H2AFV-2 H2AFV-2 ASH2L ASH2L LOC112209457-3 LOC112209457-3 LOC457262-4 LOC457262-4 LOC471876 LOC471876 SLC39A13 SLC39A13 LOC746468 LOC746468 LOC748850 LOC748850 ENSPTRP00000065421 ENSPTRP00000065421 LOC457262-3 LOC457262-3 LOC104001101 LOC104001101 LOC112209457-2 LOC112209457-2 LOC462508 LOC462508
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TERTTelomerase reverse transcriptase. (360 aa)
LOC471907Histone H3.1. (104 aa)
LOC107971253Histone H2A-Bbd type 2/3. (115 aa)
H2AJH2AFJ isoform 2. (129 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (548 aa)
H2BC21HIST2H2BE isoform 1. (126 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
HIST1H2AEHistone cluster 1 H2A family member e. (130 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC471883Histone H2B type 1. (126 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
H2BC5HIST1H2BD isoform 1. (126 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ENSPTRP00000074115annotation not available (54 aa)
LOC112209457-4Histone H3.1. (136 aa)
LOC471883-2Histone H2B type 1. (126 aa)
LOC107971249-2Histone H2A-Bbd type 2/3. (115 aa)
CREBBPCREB binding protein. (2442 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (454 aa)
LOC746430Uncharacterized LOC746430. (136 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
H4C8Histone H4. (103 aa)
LOC457262-5Histone H4. (103 aa)
ENSPTRP00000078054annotation not available (132 aa)
CK820_G0051198TLE2 isoform 3. (113 aa)
LOC112209457-5Histone H3.1. (136 aa)
LOC107966300Histone H3. (136 aa)
LOC457262-6Histone H4. (103 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
TCF7Transcription factor 7. (481 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
LOC457262-7Histone H4. (103 aa)
ENSPTRP00000084305annotation not available (104 aa)
CK820_G0031483H2AFV isoform 8. (118 aa)
LOC457262-8Histone H4. (103 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
H2BC14HIST1H2BM isoform 1. (126 aa)
H3F3BH3 histone family member 3B. (136 aa)
LOC462509HIST1H2BO isoform 1. (126 aa)
LOC457262-9Histone H4. (103 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa)
TLE2Transducin-like enhancer of split 2. (716 aa)
TLE1Transducin-like enhancer of split 1. (814 aa)
CTNNB1Catenin (Cadherin-associated protein), beta 1, 88kDa. (781 aa)
KMT2DKMT2D isoform 2. (5542 aa)
LOC107971249Histone H2A; Belongs to the histone H2A family. (115 aa)
H2AFVH2AFV isoform 6. (128 aa)
H2AC14HIST1H2AJ isoform 1. (128 aa)
H2BC11HIST1H2BJ isoform 1. (126 aa)
LOC112209457HIST1H3A isoform 1. (136 aa)
H2AC6HIST1H2AC isoform 1. (130 aa)
LOC462501HIST1H2BK isoform 1. (126 aa)
LOC457262-2Histone H4. (103 aa)
HIST1H2BBHIST1H2BB isoform 1. (126 aa)
LOC748495HIST1H2AB isoform 1. (130 aa)
HIST1H2BAHIST1H2BA isoform 1. (127 aa)
TERT-2Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (762 aa)
H2BC9HIST1H2BH isoform 1. (126 aa)
H2AZ1H2AFZ isoform 3. (128 aa)
EP300E1A binding protein p300. (2175 aa)
HIST1H3AH3F3B isoform 13. (136 aa)
TCF7L1Transcription factor 7 like 1. (587 aa)
TLE6TLE family member 6, subcortical maternal complex member. (572 aa)
AXIN2AXIN2 isoform 1. (843 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog. (666 aa)
H2AC7Histone H2A type 1-D. (130 aa)
LOC457262HIST1H4A isoform 1. (103 aa)
H2AFXH2AFX isoform 1. (143 aa)
BCL9LB-cell CLL/lymphoma 9-like. (1499 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
MEN1MEN1 isoform 14. (615 aa)
LOC469702Histone H2B type 3-A. (126 aa)
PYGO2Pygopus family PHD finger 2. (405 aa)
H3-4HIST3H3 isoform 1. (136 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
H2BU1HIST3H2BB isoform 1. (126 aa)
CDC73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog. (531 aa)
LOC457262-10Histone H4. (103 aa)
ENSPTRP00000090987annotation not available (87 aa)
H2BC6Histone H2B type 1. (126 aa)
LOC471875Histone H3.1-like. (136 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSPTRP00000092628annotation not available (129 aa)
LOC112209457-6Histone H3.1. (136 aa)
H3C13HIST2H3A isoform 1. (136 aa)
LOC104001083Histone H3.1. (136 aa)
LOC471880Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AFV-2H2A histone family member V. (127 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (639 aa)
LOC112209457-3Histone H3.1. (136 aa)
LOC457262-4Histone H4. (103 aa)
LOC471876Histone H3.1. (136 aa)
SLC39A13Solute carrier family 39 (Zinc transporter), member 13. (364 aa)
LOC746468HIST2H2AA3 isoform 1. (130 aa)
LOC748850HDAC2 isoform 9. (445 aa)
ENSPTRP00000065421annotation not available (120 aa)
LOC457262-3Histone H4. (103 aa)
LOC104001101Histone H3.1. (136 aa)
LOC112209457-2Histone H3.1. (136 aa)
LOC462508Histone H2B type 1-N. (167 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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