20 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PECAM1	Platelet/endothelial cell adhesion molecule. (745 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	ENSPTRP00000081537	annotation not available (449 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)
	YES1	Tyrosine-protein kinase. (558 aa)
	ENSPTRP00000092364	annotation not available (574 aa)
	PTPN11-2	Protein tyrosine phosphatase non-receptor type 11. (579 aa)
	ITGB3	Integrin beta-3 isoform X2. (837 aa)
	ENSPTRP00000067174	annotation not available (502 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	ITGAV	Integrin, alpha V (Vitronectin receptor, alpha polypeptide, antigen CD51); Belongs to the integrin alpha chain family. (1048 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
	INPP5D	Inositol polyphosphate-5-phosphatase D. (1189 aa)
	LCK	Tyrosine-protein kinase. (539 aa)
	ENSPTRP00000074763	annotation not available (520 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	ENSPTRP00000077211	annotation not available (269 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000067174	ENSPTRP00000081537	ENSPTRP00000067174	ENSPTRP00000081537	annotation not available	annotation not available	0.614
ENSPTRP00000067174	FYN	ENSPTRP00000067174	ENSPTRP00000077482	annotation not available	Tyrosine-protein kinase.	0.842
ENSPTRP00000067174	INPP5D	ENSPTRP00000067174	ENSPTRP00000022311	annotation not available	Inositol polyphosphate-5-phosphatase D.	0.569
ENSPTRP00000067174	ITGB3	ENSPTRP00000067174	ENSPTRP00000068323	annotation not available	Integrin beta-3 isoform X2.	0.425
ENSPTRP00000067174	LCK	ENSPTRP00000067174	ENSPTRP00000000842	annotation not available	Tyrosine-protein kinase.	0.565
ENSPTRP00000067174	LYN	ENSPTRP00000067174	ENSPTRP00000046608	annotation not available	Tyrosine-protein kinase.	0.604
ENSPTRP00000067174	PECAM1	ENSPTRP00000067174	ENSPTRP00000080846	annotation not available	Platelet/endothelial cell adhesion molecule.	0.983
ENSPTRP00000067174	PLCG1	ENSPTRP00000067174	ENSPTRP00000023178	annotation not available	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.545
ENSPTRP00000067174	PTPN6	ENSPTRP00000067174	ENSPTRP00000050501	annotation not available	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.508
ENSPTRP00000067174	SRC	ENSPTRP00000067174	ENSPTRP00000076797	annotation not available	Tyrosine-protein kinase.	0.861
ENSPTRP00000067174	YES1	ENSPTRP00000067174	ENSPTRP00000090543	annotation not available	Tyrosine-protein kinase.	0.614
ENSPTRP00000074763	ENSPTRP00000081537	ENSPTRP00000074763	ENSPTRP00000081537	annotation not available	annotation not available	0.579
ENSPTRP00000074763	FYN	ENSPTRP00000074763	ENSPTRP00000077482	annotation not available	Tyrosine-protein kinase.	0.757
ENSPTRP00000074763	INPP5D	ENSPTRP00000074763	ENSPTRP00000022311	annotation not available	Inositol polyphosphate-5-phosphatase D.	0.547
ENSPTRP00000074763	LCK	ENSPTRP00000074763	ENSPTRP00000000842	annotation not available	Tyrosine-protein kinase.	0.527
ENSPTRP00000074763	LYN	ENSPTRP00000074763	ENSPTRP00000046608	annotation not available	Tyrosine-protein kinase.	0.569
ENSPTRP00000074763	PECAM1	ENSPTRP00000074763	ENSPTRP00000080846	annotation not available	Platelet/endothelial cell adhesion molecule.	0.914
ENSPTRP00000074763	PLCG1	ENSPTRP00000074763	ENSPTRP00000023178	annotation not available	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.503
ENSPTRP00000074763	PTPN6	ENSPTRP00000074763	ENSPTRP00000050501	annotation not available	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.472
ENSPTRP00000074763	SRC	ENSPTRP00000074763	ENSPTRP00000076797	annotation not available	Tyrosine-protein kinase.	0.795