STRINGSTRING
CK820_G0050308 CK820_G0050308 ENSPTRP00000060412 ENSPTRP00000060412 KXD1 KXD1 UBC UBC SMURF1 SMURF1 ARHGEF18 ARHGEF18 PARD3 PARD3 RHOA RHOA FKBP1A FKBP1A PARD3B PARD3B RPS27A RPS27A TGFB1 TGFB1 PARD6A PARD6A F11R F11R ENSPTRP00000081587 ENSPTRP00000081587 CK820_G0040570 CK820_G0040570 CK820_G0040570-2 CK820_G0040570-2 CGN CGN TGFBR2 TGFBR2 TGFBR1 TGFBR1 ENSPTRP00000071568 ENSPTRP00000071568 ENSPTRP00000067263 ENSPTRP00000067263
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CK820_G0050308T0178126 isoform 1. (382 aa)
ENSPTRP00000060412annotation not available (156 aa)
KXD1UBA52 isoform 10. (231 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
ARHGEF18Rho guanine nucleotide exchange factor 18 isoform X6. (1015 aa)
PARD3PARD3 isoform 2. (1356 aa)
RHOARas homolog family member A. (193 aa)
FKBP1APeptidylprolyl isomerase. (139 aa)
PARD3BPartitioning defective 3 homolog B isoform X1. (1205 aa)
RPS27ARPS27A isoform 1. (156 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
F11RF11R isoform 1. (322 aa)
ENSPTRP00000081587annotation not available (103 aa)
CK820_G0040570PRKCZ isoform 2. (457 aa)
CK820_G0040570-2PRKCZ isoform 4. (95 aa)
CGNCGN isoform 6. (1210 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (581 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ENSPTRP00000071568annotation not available (98 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.