STRINGSTRING
ANO2 ANO2 SRI-2 SRI-2 ASIC3 ASIC3 ASIC1 ASIC1 STOM STOM TRPC1 TRPC1 ENSPTRP00000083926 ENSPTRP00000083926 MBNL1 MBNL1 ENSPTRP00000085164 ENSPTRP00000085164 SGK1 SGK1 TRPV4 TRPV4 ENSPTRP00000085680 ENSPTRP00000085680 TRPV5 TRPV5 ANO8 ANO8 BEST2 BEST2 MCOLN1 MCOLN1 ALPK2 ALPK2 TTYH2 TTYH2 CNTD1 CNTD1 WNK4 WNK4 ASIC2 ASIC2 TRPV2 TRPV2 TRPV1 TRPV1 TRPV3 TRPV3 MLKL MLKL ASPHD1 ASPHD1 SCNN1B SCNN1B CK820_G0030361 CK820_G0030361 RYR3 RYR3 PMFBP1 PMFBP1 RYR1 RYR1 CK820_G0029100 CK820_G0029100 GIGYF1-2 GIGYF1-2 WWC2 WWC2 SCNN1G SCNN1G CLCN7 CLCN7 STOML1 STOML1 TRPM7 TRPM7 UNC79 UNC79 RIPK3 RIPK3 NALCN NALCN TSC22D1 TSC22D1 STOML3 STOML3 TPCN1 TPCN1 BEST3 BEST3 ZC3H10 ZC3H10 TRPC6 TRPC6 ANO5 ANO5 SLC9C2 SLC9C2 CASQ1 CASQ1 CASQ2 CASQ2 CLCA1 CLCA1 CLCA4 CLCA4 CLCA2 CLCA2 MCOLN3 MCOLN3 BSND BSND BEST4 BEST4 CLCNKB CLCNKB CLCN6 CLCN6 ENSPTRP00000086815 ENSPTRP00000086815 CLCN3 CLCN3 CLCNKA CLCNKA TRPM6 TRPM6 RAF1 RAF1 TTYH3-2 TTYH3-2 TRPM3 TRPM3 CALM3 CALM3 TRPM4 TRPM4 FKBP1B FKBP1B RPS27A RPS27A ASIC4 ASIC4 ANO7 ANO7 SGK2 SGK2 ANO10 ANO10 TSC22D2 TSC22D2 SLC9B1 SLC9B1 ASIC5 ASIC5 C5H5orf15 C5H5orf15 TRPC7 TRPC7 REEP2 REEP2 RIPK1 RIPK1 SLC17A4 SLC17A4 SLC17A2 SLC17A2 OSTM1 OSTM1 TTYH3 TTYH3 TSC22D4 TSC22D4 TRPV5-2 TRPV5-2 CLCN1 CLCN1 REEP4 REEP4 SGK3 SGK3 WWP1 WWP1 WNK3 WNK3 TSC22D3 TSC22D3 TRPC5 TRPC5 WWC3 WWC3 CLCN5 CLCN5 CK820_G0047614 CK820_G0047614 SLC17A3 SLC17A3 TRPV6 TRPV6 TRPM5 TRPM5 TRPC4 TRPC4 TRPA1 TRPA1 CLIC2 CLIC2 TTYH1 TTYH1 UBC UBC MCOLN2 MCOLN2 ASPH ASPH TRPC3 TRPC3 SDR42E2 SDR42E2 SCNN1D SCNN1D ASPHD2 ASPHD2 REEP3 REEP3 MBNL2 MBNL2 SLC9C1 SLC9C1 TRDN TRDN ANO4 ANO4 ENSPTRP00000059607 ENSPTRP00000059607 ENSPTRP00000059986 ENSPTRP00000059986 KXD1 KXD1 ENSPTRP00000060412 ENSPTRP00000060412 ANO9 ANO9 TMEM177 TMEM177 CK820_G0042363 CK820_G0042363 TPCN2 TPCN2 NEDD4L NEDD4L LOC469373 LOC469373 ALPK3 ALPK3 CLCN1-2 CLCN1-2 SCNN1A SCNN1A RYR2 RYR2 TRPM1 TRPM1 ANO6 ANO6 CLIC2-2 CLIC2-2 CLCN2 CLCN2 MBNL3 MBNL3 ENSPTRP00000067263 ENSPTRP00000067263 TRPM2 TRPM2 ENSPTRP00000068002 ENSPTRP00000068002 BEST1 BEST1 CK820_G0010776 CK820_G0010776 ENSPTRP00000071568 ENSPTRP00000071568 CCDC88B-2 CCDC88B-2 CCDC88B CCDC88B GIGYF1 GIGYF1 TRPM8 TRPM8 CLCN4 CLCN4 TRPC4AP TRPC4AP SLC9B2 SLC9B2 WNK1 WNK1 ANO1 ANO1 ENSPTRP00000078047 ENSPTRP00000078047 ANO3 ANO3 LOC471113 LOC471113 ENSPTRP00000079594 ENSPTRP00000079594 ENSPTRP00000080278 ENSPTRP00000080278 UNC80 UNC80 SRI SRI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANO2Anoctamin. (999 aa)
SRI-2SRI isoform 5. (237 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (549 aa)
ASIC1ASIC1 isoform 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (562 aa)
STOMSTOM isoform 3. (288 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
ENSPTRP00000083926annotation not available (290 aa)
MBNL1Muscleblind like splicing regulator 1. (400 aa)
ENSPTRP00000085164annotation not available (395 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
TRPV4Transient receptor potential cation channel, subfamily V, member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
ENSPTRP00000085680annotation not available (88 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5. (732 aa)
ANO8Anoctamin. (1234 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (509 aa)
MCOLN1MCOLN1 isoform 1. (601 aa)
ALPK2ALPK2 isoform 1. (2171 aa)
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (534 aa)
CNTD1Cyclin N-terminal domain containing 1. (330 aa)
WNK4WNK lysine deficient protein kinase 4. (1282 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (563 aa)
TRPV2Transient receptor potential cation channel, subfamily V, member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
MLKLMixed lineage kinase domain like pseudokinase. (471 aa)
ASPHD1Aspartate beta-hydroxylase domain containing 1. (390 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception; Belongs to the amiloride-sensit [...] (685 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
RYR3Ryanodine receptor 3. (4873 aa)
PMFBP1Polyamine modulated factor 1 binding protein 1. (1022 aa)
RYR1RYR1 isoform 3. (5037 aa)
CK820_G0029100SRI isoform 2. (98 aa)
GIGYF1-2GRB10 interacting GYF protein 1. (1046 aa)
WWC2WW and C2 domain containing 2. (1196 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. (649 aa)
CLCN7Chloride channel protein. (805 aa)
STOML1Stomatin (EPB72)-like 1. (398 aa)
TRPM7Transient receptor potential cation channel, subfamily M, member 7. (1865 aa)
UNC79UNC79 isoform 1. (2648 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
NALCNSodium leak channel, non-selective. (1738 aa)
TSC22D1TSC22 domain family, member 1. (1072 aa)
STOML3STOML3 isoform 1. (291 aa)
TPCN1TPCN1 isoform 2. (888 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (668 aa)
ZC3H10Zinc finger CCCH-type containing 10. (434 aa)
TRPC6Transient receptor potential cation channel, subfamily C, member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
ANO5Anoctamin. (913 aa)
SLC9C2Solute carrier family 9 member C2 (putative). (1124 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
CLCA1CLCA1 isoform 1. (914 aa)
CLCA4CLCA4 isoform 1. (939 aa)
CLCA2CLCA2 isoform 1. (943 aa)
MCOLN3MCOLN3 isoform 1. (553 aa)
BSNDBSND isoform 1. (320 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (473 aa)
CLCNKBChloride channel protein. (699 aa)
CLCN6CLCN6 isoform 4; Belongs to the chloride channel (TC 2.A.49) family. (952 aa)
ENSPTRP00000086815annotation not available (145 aa)
CLCN3Chloride channel protein. (866 aa)
CLCNKAChloride channel protein. (686 aa)
TRPM6TRPM6 isoform 2. (2017 aa)
RAF1RAF1 isoform 2; Belongs to the protein kinase superfamily. (668 aa)
TTYH3-2Protein tweety homolog; Probable chloride channel. (526 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1711 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
TRPM4Transient receptor potential cation channel, subfamily M, member 4. (1306 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
RPS27ARPS27A isoform 1. (156 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (666 aa)
ANO7Anoctamin. (933 aa)
SGK2Serine/threonine-protein kinase Sgk2 isoform X1. (429 aa)
ANO10Anoctamin. (660 aa)
TSC22D2TSC22 domain family, member 2. (780 aa)
SLC9B1Solute carrier family 9 member B1. (515 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
C5H5orf15Chromosome 5 open reading frame 15. (265 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
REEP2Receptor expression-enhancing protein. (214 aa)
RIPK1Receptor (TNFRSF)-interacting serine-threonine kinase 1. (671 aa)
SLC17A4Solute carrier family 17 member 4. (497 aa)
SLC17A2Solute carrier family 17 member 2. (478 aa)
OSTM1Osteoclastogenesis associated transmembrane protein 1. (334 aa)
TTYH3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (523 aa)
TSC22D4TSC22 domain family, member 4. (395 aa)
TRPV5-2Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
CLCN1Chloride channel protein. (989 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
WNK3WNK3 isoform 5. (1797 aa)
TSC22D3TSC22 domain family, member 3. (200 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
WWC3WWC family member 3. (1201 aa)
CLCN5Chloride channel protein. (816 aa)
CK820_G0047614T0168804 isoform 3. (207 aa)
SLC17A3Solute carrier family 17 member 3. (498 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6. (765 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1172 aa)
TRPC4Transient receptor potential cation channel, subfamily C, member 4; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (460 aa)
UBCPolyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa)
MCOLN2MCOLN2 isoform 1. (566 aa)
ASPHASPH isoform 1. (762 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
SDR42E2Short chain dehydrogenase/reductase family 42E, member 2. (422 aa)
SCNN1DAmiloride-sensitive sodium channel subunit delta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. (802 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (369 aa)
REEP3Receptor expression-enhancing protein. (255 aa)
MBNL2MBNL2 isoform 2. (391 aa)
SLC9C1SLC9C1 isoform 1. (1177 aa)
TRDNTRDN isoform 1. (730 aa)
ANO4Anoctamin. (955 aa)
ENSPTRP00000059607annotation not available (407 aa)
ENSPTRP00000059986annotation not available (209 aa)
KXD1UBA52 isoform 10. (231 aa)
ENSPTRP00000060412annotation not available (156 aa)
ANO9Anoctamin. (760 aa)
TMEM177TMEM177 isoform 1. (108 aa)
CK820_G0042363TRPM4 isoform 1. (1251 aa)
TPCN2Two pore segment channel 2. (752 aa)
NEDD4LNEDD4L isoform 6. (1254 aa)
LOC469373LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 1-like. (317 aa)
ALPK3ALPK3 isoform 1. (1901 aa)
CLCN1-2Chloride voltage-gated channel 1. (989 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. (692 aa)
RYR2RYR2 isoform 1. (4941 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
ANO6Anoctamin. (931 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
CLCN2Chloride channel protein. (898 aa)
MBNL3Muscleblind like splicing regulator 3. (369 aa)
ENSPTRP00000067263Ubiquitin-large subunit ribosomal protein L40e. (119 aa)
TRPM2TRPM2 isoform 4. (1393 aa)
ENSPTRP00000068002annotation not available (297 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (664 aa)
CK820_G0010776TRPM8 isoform 5. (1112 aa)
ENSPTRP00000071568annotation not available (98 aa)
CCDC88B-2CCDC88B isoform 1. (1536 aa)
CCDC88BCoiled-coil domain containing 88B. (1481 aa)
GIGYF1GIGYF2 isoform 26. (1040 aa)
TRPM8TRPM8 isoform 2. (1104 aa)
CLCN4Chloride channel protein. (760 aa)
TRPC4APTransient receptor potential cation channel, subfamily C, member 4 associated protein. (797 aa)
SLC9B2Solute carrier family 9B (sodium/hydrogen exchanger), member 1/2. (537 aa)
WNK1WNK1 isoform 4. (2833 aa)
ANO1Anoctamin. (986 aa)
ENSPTRP00000078047annotation not available (132 aa)
ANO3Anoctamin. (1042 aa)
LOC471113NEDD4-like E3 ubiquitin-protein ligase WWP1 pseudogene. (783 aa)
ENSPTRP00000079594annotation not available (460 aa)
ENSPTRP00000080278annotation not available (136 aa)
UNC80Unc-80 homolog, NALCN channel complex subunit. (3323 aa)
SRISRI isoform 1. (205 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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