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MAPK3 MAPK3 LOC452776 LOC452776 CK820_G0055055 CK820_G0055055 LAT LAT IGKV1D-43 IGKV1D-43 SOS1 SOS1 SHC1 SHC1 FCER1G FCER1G ENSPTRP00000050833 ENSPTRP00000050833 MAP3K1 MAP3K1 LOC451223 LOC451223 LYN LYN SPNS3 SPNS3 FCRL3 FCRL3 MAPK8 MAPK8 MAPK9 MAPK9 LCP2 LCP2 CLNK CLNK PAK2 PAK2 GRAP2 GRAP2 MAPK1 MAPK1 CK820_G0046006 CK820_G0046006 PLCG1 PLCG1 VAV1 VAV1 GRB2 GRB2 MAP2K4 MAP2K4 PAK1 PAK1 MS4A10 MS4A10 MS4A15 MS4A15 MS4A8 MS4A8 MS4A12 MS4A12 MS4A4A MS4A4A MS4A2 MS4A2 HARBI1 HARBI1 HRAS HRAS FCER1A FCER1A FCRL4 FCRL4 NRAS NRAS RAC1 RAC1 MAPK10 MAPK10 ENSPTRP00000070755 ENSPTRP00000070755 ENSPTRP00000071419 ENSPTRP00000071419 CSDE1 CSDE1 CK820_G0030851 CK820_G0030851 CK820_G0054782 CK820_G0054782 ENSPTRP00000072698 ENSPTRP00000072698 CK820_G0056252 CK820_G0056252 MAP2K7 MAP2K7 SPNS1 SPNS1 SYK SYK CK820_G0052109 CK820_G0052109 ENSPTRP00000092307 ENSPTRP00000092307 IGLL5 IGLL5 CK820_G0052128 CK820_G0052128 FCRL5 FCRL5 ERAS ERAS LOC744594 LOC744594 ENSPTRP00000065882 ENSPTRP00000065882 ENSPTRP00000067835 ENSPTRP00000067835 FCRL1 FCRL1 VAV3 VAV3 ENSPTRP00000089740 ENSPTRP00000089740 CK820_G0052139 CK820_G0052139 FOSL2 FOSL2 ENSPTRP00000085718 ENSPTRP00000085718 KRAS KRAS RAC1-2 RAC1-2 VAV2 VAV2 FOS FOS CK820_G0052121 CK820_G0052121 CK820_G0055030 CK820_G0055030 PLCG2 PLCG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LOC452776TRAV22 isoform 1. (185 aa)
CK820_G0055055IGHV2-26 isoform 1. (178 aa)
LATLinker for activation of T cells. (268 aa)
IGKV1D-43IGKV1-39 isoform 1. (125 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SHC1SHC (Src homology 2 domain containing) transforming protein 1. (584 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
ENSPTRP00000050833annotation not available (151 aa)
MAP3K1MAP3K1 isoform 1. (1509 aa)
LOC451223MS4A1 isoform 1. (297 aa)
LYNTyrosine-protein kinase. (512 aa)
SPNS3Sphingolipid transporter 3 (putative). (512 aa)
FCRL3Fc receptor like 3. (742 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
PAK2Non-specific serine/threonine protein kinase. (476 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CK820_G0046006IGKV2-40 isoform 1. (122 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa)
PAK1Non-specific serine/threonine protein kinase. (553 aa)
MS4A10Membrane spanning 4-domains A10. (266 aa)
MS4A15MS4A15 isoform 4. (240 aa)
MS4A8Membrane spanning 4-domains A8. (250 aa)
MS4A12Membrane spanning 4-domains A12. (267 aa)
MS4A4AMembrane spanning 4-domains A4A. (239 aa)
MS4A2Membrane spanning 4-domains A2. (244 aa)
HARBI1Harbinger transposase derived 1. (349 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
FCER1AFCER1A isoform 1. (260 aa)
FCRL4FCRL4 isoform 1. (515 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
MAPK10Mitogen-activated protein kinase. (551 aa)
ENSPTRP00000070755annotation not available (81 aa)
ENSPTRP00000071419annotation not available (371 aa)
CSDE1Cold shock domain containing E1. (844 aa)
CK820_G0030851MS4A4E isoform 1. (154 aa)
CK820_G0054782IGLV9-49 isoform 1. (123 aa)
ENSPTRP00000072698annotation not available (130 aa)
CK820_G0056252IGHV3-30 isoform 1. (198 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (438 aa)
SPNS1Sphingolipid transporter 1 (putative). (476 aa)
SYKTyrosine-protein kinase. (635 aa)
CK820_G0052109IGLV3-1 isoform 1. (166 aa)
ENSPTRP00000092307annotation not available (161 aa)
IGLL5IGLL5 isoform 1. (215 aa)
CK820_G0052128IGLV2-14 isoform 1. (170 aa)
FCRL5Fc receptor like 5. (1027 aa)
ERASES cell expressed Ras. (233 aa)
LOC744594IGHV4-61 isoform 1. (215 aa)
ENSPTRP00000065882annotation not available (152 aa)
ENSPTRP00000067835annotation not available (192 aa)
FCRL1Fc receptor like 1. (508 aa)
VAV3VAV3 isoform 2. (927 aa)
ENSPTRP00000089740annotation not available (123 aa)
CK820_G0052139IGLV2-23 isoform 1. (170 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
ENSPTRP00000085718annotation not available (180 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CK820_G0052121IGLV3-10 isoform 1. (148 aa)
CK820_G0055030IGHV1-2 isoform 1. (159 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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