61 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TXNRD1	TXNRD1 isoform 3. (648 aa)
	GPX8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	GPX5	Glutathione peroxidase 5. (211 aa)
	NCF4	Neutrophil cytosolic factor 4. (368 aa)
	LOC100615743	Peroxiredoxin-1-like. (171 aa)
	ERO1A	Endoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
	NME9	NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
	PDIA2	PDIA2 isoform 1. (306 aa)
	ENSPTRP00000079686	annotation not available (213 aa)
	ENSPTRP00000081633	annotation not available (139 aa)
	LOC104002760	Cytochrome c. (110 aa)
	SOD2	Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (238 aa)
	ENSPTRP00000084892	annotation not available (374 aa)
	TXN2	Thioredoxin, mitochondrial. (201 aa)
	ENSPTRP00000089486	annotation not available (110 aa)
	ENSPTRP00000091402	annotation not available (93 aa)
	CYBA	Cytochrome b-245 alpha chain. (210 aa)
	TXNDC8	TXNDC8 isoform 1. (123 aa)
	ENSPTRP00000091826	annotation not available (117 aa)
	ENSPTRP00000093174	annotation not available (208 aa)
	LOC742456	Cytochrome c-like. (105 aa)
	SOD3	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
	TXNRD3	TXNRD3 isoform 1. (642 aa)
	SOD1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	PRDX2	PRDX2 isoform 1. (198 aa)
	P4HB	Protein disulfide-isomerase. (508 aa)
	AQP8	AQP8 isoform 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	CCS	Copper chaperone for superoxide dismutase. (274 aa)
	PRDX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (214 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	PRDX3	PRDX3 isoform 1. (256 aa)
	NCF2	Neutrophil cytosolic factor 2. (526 aa)
	PRDX1	PRDX1 isoform 1. (199 aa)
	CYCS	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
	NPVF	Neuropeptide VF precursor. (196 aa)
	NME8	NME/NM23 family member 8. (588 aa)
	NCF1	Neutrophil cytosolic factor 1. (390 aa)
	GSR	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
	NUDT2	Nudix (Nucleoside diphosphate linked moiety X)-type motif 2. (147 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	GPX7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa)
	CYBB	Cytochrome b-245 beta chain. (570 aa)
	NOX4	NADPH oxidase 4. (578 aa)
	GSTP1	Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
	GPX3	GPX3 isoform 3. (225 aa)
	TXNDC2	TXNDC2 isoform 2. (520 aa)
	GPX6	Glutathione peroxidase 6 precursor. (220 aa)
	GPX1	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (200 aa)
	NOX5	NADPH oxidase 5. (737 aa)
	GPX2	GPX2 isoform 4. (150 aa)
	TXNRD2	TXNRD2 isoform 6. (517 aa)
	PRDX6	PRDX6 isoform 1. (224 aa)
	ENSPTRP00000063547	Cytochrome c. (105 aa)
	ATP7A	ATPase, Cu++ transporting, alpha polypeptide. (1500 aa)
	LOC107972317	Cytochrome c-like. (102 aa)
	ATOX1	Antioxidant 1 copper chaperone. (73 aa)
	ENSPTRP00000066724	annotation not available (166 aa)
	LOC100616026	Thioredoxin-like. (106 aa)
	ENSPTRP00000068695	annotation not available (105 aa)
	NOX4-2	NADPH oxidase 4. (225 aa)
	LOC736283	Glutathione peroxidase 1 pseudogene. (188 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOX1	ATP7A	ENSPTRP00000066520	ENSPTRP00000064175	Antioxidant 1 copper chaperone.	ATPase, Cu++ transporting, alpha polypeptide.	0.992
ATOX1	CCS	ENSPTRP00000066520	ENSPTRP00000006775	Antioxidant 1 copper chaperone.	Copper chaperone for superoxide dismutase.	0.762
ATOX1	ENSPTRP00000079686	ENSPTRP00000066520	ENSPTRP00000079686	Antioxidant 1 copper chaperone.	annotation not available	0.501
ATOX1	PRDX3	ENSPTRP00000066520	ENSPTRP00000005275	Antioxidant 1 copper chaperone.	PRDX3 isoform 1.	0.501
ATOX1	PRDX5	ENSPTRP00000066520	ENSPTRP00000006599	Antioxidant 1 copper chaperone.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.489
ATOX1	SOD1	ENSPTRP00000066520	ENSPTRP00000023837	Antioxidant 1 copper chaperone.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.791
ATOX1	SOD3	ENSPTRP00000066520	ENSPTRP00000027474	Antioxidant 1 copper chaperone.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.775
ATP7A	ATOX1	ENSPTRP00000064175	ENSPTRP00000066520	ATPase, Cu++ transporting, alpha polypeptide.	Antioxidant 1 copper chaperone.	0.992
ATP7A	CCS	ENSPTRP00000064175	ENSPTRP00000006775	ATPase, Cu++ transporting, alpha polypeptide.	Copper chaperone for superoxide dismutase.	0.985
ATP7A	GSTP1	ENSPTRP00000064175	ENSPTRP00000047877	ATPase, Cu++ transporting, alpha polypeptide.	Glutathione S-transferase pi 1; Belongs to the GST superfamily.	0.517
ATP7A	SOD1	ENSPTRP00000064175	ENSPTRP00000023837	ATPase, Cu++ transporting, alpha polypeptide.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.596
ATP7A	SOD2	ENSPTRP00000064175	ENSPTRP00000083441	ATPase, Cu++ transporting, alpha polypeptide.	Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.415
ATP7A	SOD3	ENSPTRP00000064175	ENSPTRP00000027474	ATPase, Cu++ transporting, alpha polypeptide.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.738
CAT	ENSPTRP00000066724	ENSPTRP00000006074	ENSPTRP00000066724	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	annotation not available	0.630
CAT	ENSPTRP00000079686	ENSPTRP00000006074	ENSPTRP00000079686	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	annotation not available	0.630
CAT	ENSPTRP00000081633	ENSPTRP00000006074	ENSPTRP00000081633	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	annotation not available	0.429
CAT	ENSPTRP00000093174	ENSPTRP00000006074	ENSPTRP00000093174	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	annotation not available	0.674
CAT	GPX1	ENSPTRP00000006074	ENSPTRP00000051383	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.	0.429
CAT	GPX2	ENSPTRP00000006074	ENSPTRP00000052602	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	GPX2 isoform 4.	0.429
CAT	GPX3	ENSPTRP00000006074	ENSPTRP00000047900	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	GPX3 isoform 3.	0.429