36 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HDAC2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa)
	MAML1	MAML1 isoform 1. (1016 aa)
	NOTCH4	NOTCH4 isoform 3. (2006 aa)
	SNW1	SNW domain containing 1. (571 aa)
	MAMLD1	MAMLD1 isoform 3. (984 aa)
	LOC748850	HDAC2 isoform 9. (445 aa)
	TBL1X	Transducin (Beta)-like 1X-linked. (571 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)
	CREBBP	CREB binding protein. (2442 aa)
	HDAC10	Histone deacetylase 10. (669 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
	NOTCH1	NOTCH1 isoform 1. (2555 aa)
	MAML2	Mastermind like transcriptional coactivator 2. (1150 aa)
	KAT2A	Histone acetyltransferase KAT2A isoform X1. (837 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1115 aa)
	ENSPTRP00000082196	annotation not available (376 aa)
	TBL1XR1	Transducin (Beta)-like 1 X-linked receptor 1. (562 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1016 aa)
	NCOR2	Nuclear receptor corepressor 2. (2514 aa)
	TBL1Y	TBL1X isoform 5. (533 aa)
	HDAC6	Histone deacetylase 6. (146 aa)
	ENSPTRP00000087746	annotation not available (429 aa)
	HDAC11	HDAC11 isoform 14. (374 aa)
	HDAC8	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (396 aa)
	ENSPTRP00000081714	annotation not available (310 aa)
	MAMLD1-2	Mastermind-like domain containing 1. (722 aa)
	MAML3	MAML3 isoform 1. (1134 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (500 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	NOTCH2	NOTCH2 isoform 1. (2612 aa)
	NCOR1	Nuclear receptor corepressor 1. (2442 aa)
	NOTCH3	NOTCH3 isoform 1. (2321 aa)
	RBPJL	Recombination signal binding protein for immunoglobulin kappa J region like. (517 aa)
	CRB1	Crumbs cell polarity complex component 1. (1406 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRB1	ENSPTRP00000082196	ENSPTRP00000046227	ENSPTRP00000082196	Crumbs cell polarity complex component 1.	annotation not available	0.408
CRB1	ENSPTRP00000087746	ENSPTRP00000046227	ENSPTRP00000087746	Crumbs cell polarity complex component 1.	annotation not available	0.408
CRB1	NOTCH1	ENSPTRP00000046227	ENSPTRP00000036924	Crumbs cell polarity complex component 1.	NOTCH1 isoform 1.	0.440
CRB1	RBPJ	ENSPTRP00000046227	ENSPTRP00000079413	Crumbs cell polarity complex component 1.	Recombination signal binding protein for immunoglobulin kappa J region.	0.408
CRB1	RBPJL	ENSPTRP00000046227	ENSPTRP00000023259	Crumbs cell polarity complex component 1.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.408
CREBBP	ENSPTRP00000081714	ENSPTRP00000074980	ENSPTRP00000081714	CREB binding protein.	annotation not available	0.654
CREBBP	ENSPTRP00000082196	ENSPTRP00000074980	ENSPTRP00000082196	CREB binding protein.	annotation not available	0.647
CREBBP	ENSPTRP00000087746	ENSPTRP00000074980	ENSPTRP00000087746	CREB binding protein.	annotation not available	0.647
CREBBP	HDAC1	ENSPTRP00000074980	ENSPTRP00000075891	CREB binding protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.808
CREBBP	HDAC10	ENSPTRP00000074980	ENSPTRP00000025053	CREB binding protein.	Histone deacetylase 10.	0.491
CREBBP	HDAC11	ENSPTRP00000074980	ENSPTRP00000084825	CREB binding protein.	HDAC11 isoform 14.	0.559
CREBBP	HDAC2	ENSPTRP00000074980	ENSPTRP00000049696	CREB binding protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.803
CREBBP	HDAC3	ENSPTRP00000074980	ENSPTRP00000029652	CREB binding protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.810
CREBBP	HDAC4	ENSPTRP00000074980	ENSPTRP00000073000	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.568
CREBBP	HDAC5	ENSPTRP00000074980	ENSPTRP00000015756	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.665
CREBBP	HDAC6	ENSPTRP00000074980	ENSPTRP00000037550	CREB binding protein.	Histone deacetylase 6.	0.564
CREBBP	HDAC7	ENSPTRP00000074980	ENSPTRP00000088885	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.540
CREBBP	HDAC8	ENSPTRP00000074980	ENSPTRP00000082283	CREB binding protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.594
CREBBP	HDAC9	ENSPTRP00000074980	ENSPTRP00000032389	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.668
CREBBP	KAT2A	ENSPTRP00000074980	ENSPTRP00000015659	CREB binding protein.	Histone acetyltransferase KAT2A isoform X1.	0.980