STRINGSTRING
ENSPTRP00000068916 ENSPTRP00000068916 NEDD9 NEDD9 PDPK1 PDPK1 CASS4 CASS4 FNDC3B FNDC3B RAP1A RAP1A FNDC3A FNDC3A PTK2 PTK2 FGG FGG CRK CRK AKT1 AKT1 BCAR1 BCAR1 SRC SRC ENSPTRP00000076429 ENSPTRP00000076429 SYK SYK RASGRP1 RASGRP1 TLN1 TLN1 RAP1B RAP1B ITGB3 ITGB3 RAPGEFL1 RAPGEFL1 RAPGEF4 RAPGEF4 RAPGEF5 RAPGEF5 SOS1 SOS1 SHC1 SHC1 RAPH1 RAPH1 PTPN1 PTPN1 FN1 FN1 FGA FGA FGB FGB GRB2 GRB2 ITGA2B ITGA2B CSK CSK TLN2 TLN2 EFS EFS RAPGEF3 RAPGEF3 VWF VWF RASGRP2 RASGRP2 APBB1IP APBB1IP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPTRP00000068916annotation not available (99 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
CASS4CASS4 isoform 2. (812 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
FGGFibrinogen gamma chain. (453 aa)
CRKV-crk sarcoma virus CT10 oncogene homolog (Avian). (304 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
SRCTyrosine-protein kinase. (542 aa)
ENSPTRP00000076429annotation not available (110 aa)
SYKTyrosine-protein kinase. (635 aa)
RASGRP1RASGRP1 isoform 4. (848 aa)
TLN1TLN1 isoform 1. (2558 aa)
RAP1BRas-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa)
ITGB3Integrin beta-3 isoform X2. (837 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (662 aa)
RAPGEF4RAPGEF4 isoform 2. (1011 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SHC1SHC (Src homology 2 domain containing) transforming protein 1. (584 aa)
RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1302 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
FN1FN1 isoform 1. (2477 aa)
FGAFibrinogen alpha chain. (866 aa)
FGBFibrinogen beta chain. (491 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
ITGA2BITGA2B isoform 3; Belongs to the integrin alpha chain family. (1032 aa)
CSKTyrosine-protein kinase. (450 aa)
TLN2TLN2 isoform 1. (2544 aa)
EFSEmbryonal Fyn-associated substrate. (560 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
VWFVon Willebrand factor. (2813 aa)
RASGRP2RAS guanyl releasing protein 2. (609 aa)
APBB1IPAPBB1IP isoform 1. (665 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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