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COL4A3 COL4A3 COL9A1 COL9A1 ST8SIA4 ST8SIA4 CK820_G0023028 CK820_G0023028 COL4A1 COL4A1 ENSPTRP00000089337 ENSPTRP00000089337 GFRA1 GFRA1 CACNB3 CACNB3 CACNB1 CACNB1 CNTN2 CNTN2 ARTN ARTN KRAS KRAS PTK2 PTK2 FYN FYN ST8SIA2 ST8SIA2 SRC SRC COL9A2 COL9A2 CACNA1D CACNA1D SPTBN5 SPTBN5 PRNP PRNP CACNA1S CACNA1S SPTBN4 SPTBN4 COL5A1 COL5A1 CREB1 CREB1 CSDE1 CSDE1 SPTBN1 SPTBN1 NCAM2 NCAM2 PSPN PSPN COL4A5 COL4A5 RPS6KA5 RPS6KA5 CACNA1G CACNA1G FGFR1 FGFR1 SPTAN1 SPTAN1 ERAS ERAS NCAM1 NCAM1 COL4A2 COL4A2 CACNA1I CACNA1I CACNB4 CACNB4 PTPRA PTPRA MAPK3 MAPK3 SPTB SPTB SOS1 SOS1 COL5A2 COL5A2 COL4A4 COL4A4 PTPRE PTPRE CACNB2 CACNB2 COL2A1 COL2A1 SPTBN2 SPTBN2 AGRN AGRN GFRA2 GFRA2 COL6A5 COL6A5 COL6A6 COL6A6 MAPK1 MAPK1 COL6A2 COL6A2 COL9A3 COL9A3 GFRA4 GFRA4 COL6A3 COL6A3 COL3A1 COL3A1 COL5A3 COL5A3 NRTN NRTN GRB2 GRB2 CACNA1H CACNA1H CACNA1C CACNA1C HRAS HRAS SPTA1 SPTA1 NRAS NRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL4A3Collagen type IV alpha 3 chain. (1670 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
ST8SIA4CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. (359 aa)
CK820_G0023028COL6A2 isoform 1. (417 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
ENSPTRP00000089337annotation not available (2012 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
ARTNARTN isoform 11. (235 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
FYNTyrosine-protein kinase. (537 aa)
ST8SIA2Alpha-2,8-sialyltransferase 8B; May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression. (375 aa)
SRCTyrosine-protein kinase. (542 aa)
COL9A2Collagen type IX alpha 2 chain. (689 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
SPTBN5LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 5. (3705 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
COL5A1Collagen type V alpha 1 chain. (1841 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CSDE1Cold shock domain containing E1. (844 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2366 aa)
NCAM2Neural cell adhesion molecule 2. (862 aa)
PSPNPSPN isoform 2. (156 aa)
COL4A5Collagen type IV alpha 5 chain. (1691 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
FGFR1Fibroblast growth factor receptor. (854 aa)
SPTAN1SPTAN1 isoform 9. (2498 aa)
ERASES cell expressed Ras. (233 aa)
NCAM1Neural cell adhesion molecule 1. (884 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2223 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2265 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
COL4A4COL4A4 isoform 1. (1690 aa)
PTPREReceptor-type tyrosine-protein phosphatase. (700 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
AGRNAGRN isoform 2. (2066 aa)
GFRA2GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (464 aa)
COL6A5COL6A5 isoform 2. (2625 aa)
COL6A6Collagen, type VI, alpha 6. (2263 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
COL6A2COL6A2 isoform 4. (444 aa)
COL9A3Collagen type IX alpha 3 chain. (684 aa)
GFRA4GFRA4 isoform 1. (269 aa)
COL6A3COL6A3 isoform 2. (3177 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL5A3Collagen type V alpha 3 chain. (1745 aa)
NRTNNRTN isoform 1. (197 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
CACNA1HCACNA1H isoform 1. (2240 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
SPTA1SPTA1 isoform 1. (2419 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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