52 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNB2	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
	GNB2-2	G protein subunit beta 2. (372 aa)
	THAP6	THAP domain containing 6. (222 aa)
	ENSPTRP00000093443	annotation not available (57 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	CK820_G0040666	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	ITPR3	ITPR3 isoform 1. (2677 aa)
	GNB4	Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
	ADCY5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1236 aa)
	ITPR1	ITPR1 isoform 3. (2700 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
	THAP7	THAP domain containing 7. (309 aa)
	KCNB1	Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
	FAP	Fibroblast activation protein, alpha; Belongs to the peptidase S9B family. (760 aa)
	KCNS3	Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
	PRKACA	PRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
	KCNG2	Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (467 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	GNB5	GNB5 isoform 1. (409 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (923 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	PRKACG	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10. (68 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	PRKAR1A	Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1). (381 aa)
	GCG	GCG isoform 1. (180 aa)
	AKAP5	A-kinase anchoring protein 5. (427 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (730 aa)
	GNAS	GNAS isoform 19. (1042 aa)
	PRKAR2B	Protein kinase, cAMP-dependent, regulatory, type II, beta. (418 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
	RAPGEF4	RAPGEF4 isoform 2. (1011 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	GNG13	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	GNB1	Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
	RAPGEFL1	Rap guanine nucleotide exchange factor like 1. (662 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	ENSPTRP00000071036	annotation not available (68 aa)
	ENSPTRP00000076429	annotation not available (110 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	KCNC2	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
	ENSPTRP00000083779	annotation not available (309 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	ADCY6	ENSPTRP00000026385	ENSPTRP00000093557	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.957
ADCY5	ADCY8	ENSPTRP00000026385	ENSPTRP00000077396	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.578
ADCY5	AKAP5	ENSPTRP00000026385	ENSPTRP00000052611	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	A-kinase anchoring protein 5.	0.821
ADCY5	CK820_G0040666	ENSPTRP00000026385	ENSPTRP00000093662	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.481
ADCY5	GCG	ENSPTRP00000026385	ENSPTRP00000049083	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GCG isoform 1.	0.421
ADCY5	GNAS	ENSPTRP00000026385	ENSPTRP00000059419	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS isoform 19.	0.982
ADCY5	GNB1	ENSPTRP00000026385	ENSPTRP00000067330	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.776
ADCY5	GNB2	ENSPTRP00000026385	ENSPTRP00000085287	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.770
ADCY5	GNB3	ENSPTRP00000026385	ENSPTRP00000045189	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.774
ADCY5	GNB4	ENSPTRP00000026385	ENSPTRP00000026924	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide binding protein (G protein), beta polypeptide 4.	0.770
ADCY5	GNB5	ENSPTRP00000026385	ENSPTRP00000012110	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNB5 isoform 1.	0.811
ADCY5	GNG10	ENSPTRP00000026385	ENSPTRP00000036311	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10.	0.774
ADCY5	GNG11	ENSPTRP00000026385	ENSPTRP00000033202	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.804
ADCY5	GNG12	ENSPTRP00000026385	ENSPTRP00000062287	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.786
ADCY5	GNG13	ENSPTRP00000026385	ENSPTRP00000062938	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.808
ADCY5	GNG2	ENSPTRP00000026385	ENSPTRP00000065345	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.855
ADCY5	GNG3	ENSPTRP00000026385	ENSPTRP00000006503	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.793
ADCY5	GNG4	ENSPTRP00000026385	ENSPTRP00000003602	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.800
ADCY5	GNG7	ENSPTRP00000026385	ENSPTRP00000069136	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.817
ADCY5	GNG8	ENSPTRP00000026385	ENSPTRP00000090253	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.783