39 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNBP4	Formin binding protein 4. (1019 aa)
	PPP2CA	PPP2CB isoform 8. (309 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	PPP4R1	Protein phosphatase 4, regulatory subunit 1. (950 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
	ENSPTRP00000029492	annotation not available (223 aa)
	CD86	CD86 isoform 3. (329 aa)
	CD80	CD80 isoform 1. (288 aa)
	CD276	CD276 isoform 13. (534 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (667 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	ENSPTRP00000064286	annotation not available (260 aa)
	LCK	Tyrosine-protein kinase. (539 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
	ENSPTRP00000092364	annotation not available (574 aa)
	YES1	Tyrosine-protein kinase. (558 aa)
	PPP4R4	Protein phosphatase 4, regulatory subunit 4. (873 aa)
	CK820_G0024820	PPP2R5C isoform 26. (479 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (454 aa)
	LOC100612020	Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1. (954 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	PPP2R1A	Protein phosphatase 2, regulatory subunit A, alpha. (637 aa)
	AKT1	AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
	ENSPTRP00000081537	annotation not available (449 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (223 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	ENSPTRP00000077211	annotation not available (269 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	ENSPTRP00000074763	annotation not available (520 aa)
	PTPN11-2	Protein tyrosine phosphatase non-receptor type 11. (579 aa)
	ENSPTRP00000067174	annotation not available (502 aa)
	ENSPTRP00000065717	annotation not available (260 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSPTRP00000082849	ENSPTRP00000089692	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.988
AKT1	AKT3	ENSPTRP00000082849	ENSPTRP00000086046	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.951
AKT1	CD80	ENSPTRP00000082849	ENSPTRP00000026304	AKT1 isoform 3; Belongs to the protein kinase superfamily.	CD80 isoform 1.	0.603
AKT1	CD86	ENSPTRP00000082849	ENSPTRP00000026356	AKT1 isoform 3; Belongs to the protein kinase superfamily.	CD86 isoform 3.	0.627
AKT1	CK820_G0024820	ENSPTRP00000082849	ENSPTRP00000089833	AKT1 isoform 3; Belongs to the protein kinase superfamily.	PPP2R5C isoform 26.	0.426
AKT1	CTLA4	ENSPTRP00000082849	ENSPTRP00000080210	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Cytotoxic T-lymphocyte associated protein 4.	0.615
AKT1	ENSPTRP00000029492	ENSPTRP00000082849	ENSPTRP00000029492	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.894
AKT1	ENSPTRP00000067174	ENSPTRP00000082849	ENSPTRP00000067174	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.531
AKT1	ENSPTRP00000074763	ENSPTRP00000082849	ENSPTRP00000074763	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.457
AKT1	ENSPTRP00000077211	ENSPTRP00000082849	ENSPTRP00000077211	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.457
AKT1	ENSPTRP00000081537	ENSPTRP00000082849	ENSPTRP00000081537	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.582
AKT1	ENSPTRP00000092364	ENSPTRP00000082849	ENSPTRP00000092364	AKT1 isoform 3; Belongs to the protein kinase superfamily.	annotation not available	0.457
AKT1	FYN	ENSPTRP00000082849	ENSPTRP00000077482	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.707
AKT1	LCK	ENSPTRP00000082849	ENSPTRP00000000842	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.707
AKT1	LYN	ENSPTRP00000082849	ENSPTRP00000046608	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.682
AKT1	PPP2CA	ENSPTRP00000082849	ENSPTRP00000063523	AKT1 isoform 3; Belongs to the protein kinase superfamily.	PPP2CB isoform 8.	0.961
AKT1	PPP2CB	ENSPTRP00000082849	ENSPTRP00000087981	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.860
AKT1	PPP2R1A	ENSPTRP00000082849	ENSPTRP00000083529	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Protein phosphatase 2, regulatory subunit A, alpha.	0.873
AKT1	PPP2R1B	ENSPTRP00000082849	ENSPTRP00000007340	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Protein phosphatase 2 scaffold subunit Abeta.	0.837
AKT1	PPP2R5A	ENSPTRP00000082849	ENSPTRP00000079578	AKT1 isoform 3; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.800