40 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	GNAI3	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	GNB5	GNB5 isoform 1. (409 aa)
	GNA13	Guanine nucleotide binding protein (G protein), alpha 13. (377 aa)
	AAMP	Angio associated migratory cell protein. (435 aa)
	GNAI2	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. (355 aa)
	P2RY1	Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	GNB4	Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
	MAPK14	Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10. (68 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	GNAQ	Guanine nucleotide binding protein (G protein), q polypeptide. (359 aa)
	GNAT3	G protein subunit alpha transducin 3. (354 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
	TBXA2R	Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
	GNG13	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	GNB1	Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSPTRP00000070111	annotation not available (324 aa)
	ENSPTRP00000071036	annotation not available (68 aa)
	GNAI1	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa)
	GNA11	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class). (359 aa)
	ENSPTRP00000075783	annotation not available (149 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	ENSPTRP00000077377	annotation not available (149 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)
	GNB2	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	GNA14	Guanine nucleotide binding protein (G protein), alpha 14. (355 aa)
	GNB2-2	G protein subunit beta 2. (372 aa)
	ENSPTRP00000093443	annotation not available (57 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	CK820_G0040666	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAMP	TBXA2R	ENSPTRP00000022072	ENSPTRP00000062372	Angio associated migratory cell protein.	Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family.	0.801
CK820_G0040666	ENSPTRP00000070111	ENSPTRP00000093662	ENSPTRP00000070111	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	annotation not available	0.779
CK820_G0040666	ENSPTRP00000071036	ENSPTRP00000093662	ENSPTRP00000071036	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	annotation not available	0.741
CK820_G0040666	ENSPTRP00000075783	ENSPTRP00000093662	ENSPTRP00000075783	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	annotation not available	0.541
CK820_G0040666	ENSPTRP00000077377	ENSPTRP00000093662	ENSPTRP00000077377	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	annotation not available	0.541
CK820_G0040666	ENSPTRP00000093443	ENSPTRP00000093662	ENSPTRP00000093443	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	annotation not available	0.705
CK820_G0040666	GNA11	ENSPTRP00000093662	ENSPTRP00000074292	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha 11 (Gq class).	0.783
CK820_G0040666	GNA13	ENSPTRP00000093662	ENSPTRP00000016220	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha 13.	0.833
CK820_G0040666	GNA14	ENSPTRP00000093662	ENSPTRP00000091799	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha 14.	0.783
CK820_G0040666	GNA15	ENSPTRP00000093662	ENSPTRP00000093570	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit alpha 15.	0.818
CK820_G0040666	GNAI1	ENSPTRP00000093662	ENSPTRP00000071974	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.848
CK820_G0040666	GNAI2	ENSPTRP00000093662	ENSPTRP00000025802	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.847
CK820_G0040666	GNAI3	ENSPTRP00000093662	ENSPTRP00000001821	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.915
CK820_G0040666	GNAQ	ENSPTRP00000093662	ENSPTRP00000049267	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.779
CK820_G0040666	GNAT3	ENSPTRP00000093662	ENSPTRP00000055752	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit alpha transducin 3.	0.806
CK820_G0040666	GNB1	ENSPTRP00000093662	ENSPTRP00000067330	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.996
CK820_G0040666	GNB2	ENSPTRP00000093662	ENSPTRP00000085287	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.936
CK820_G0040666	GNB2-2	ENSPTRP00000093662	ENSPTRP00000092592	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 2.	0.969
CK820_G0040666	GNB3	ENSPTRP00000093662	ENSPTRP00000045189	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 3.	0.996
CK820_G0040666	GNB4	ENSPTRP00000093662	ENSPTRP00000026924	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 4.	0.996