STRINGSTRING
AP2B1 AP2B1 ACTRT1 ACTRT1 ACTL7A ACTL7A ACTL7B ACTL7B CLTA CLTA CK820_G0053598 CK820_G0053598 EPHA1 EPHA1 EPHB6 EPHB6 EPHB4 EPHB4 PSENEN PSENEN ENSPTRP00000016618 ENSPTRP00000016618 APH1B APH1B ADAM10 ADAM10 PSEN1 PSEN1 EFNB2 EFNB2 AP2A2 AP2A2 EFNA1 EFNA1 EFNA3 EFNA3 EFNA4 EFNA4 EPHA10 EPHA10 EPHA8 EPHA8 EPHA2 EPHA2 ACTRT2 ACTRT2 EPHA7 EPHA7 EFNA5 EFNA5 EPHA5 EPHA5 EPHA6 EPHA6 EPHA3 EPHA3 TIAM1 TIAM1 CLTC CLTC NCSTN NCSTN ENSPTRP00000093517 ENSPTRP00000093517 YES1 YES1 EPHA1-2 EPHA1-2 VAV3 VAV3 EFNB1 EFNB1 AP2S1 AP2S1 EFNB3 EFNB3 MMP2 MMP2 DNM1-2 DNM1-2 EPHA4 EPHA4 FNDC3B FNDC3B MMP9 MMP9 RAC1-2 RAC1-2 DNM1 DNM1 VAV2 VAV2 FNDC3A FNDC3A ENSPTRP00000081537 ENSPTRP00000081537 CLTB CLTB ENSPTRP00000080740 ENSPTRP00000080740 ACTG1 ACTG1 CK820_G0023066 CK820_G0023066 AP2M1 AP2M1 EPHB4-2 EPHB4-2 FYN FYN ENSPTRP00000076988 ENSPTRP00000076988 SRC SRC CLTCL1 CLTCL1 EPHB3 EPHB3 ENSPTRP00000070878 ENSPTRP00000070878 RAC1 RAC1 AP2A1 AP2A1 LOC736439 LOC736439 ENSPTRP00000064849 ENSPTRP00000064849 ACTL9 ACTL9 ACTB ACTB EPHB1 EPHB1 EPHB2 EPHB2 PSEN2 PSEN2 EFNA2 EFNA2 ELSPBP1 ELSPBP1 LYN LYN LOC744297 LOC744297 APH1A APH1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP2B1AP complex subunit beta. (951 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (376 aa)
ACTL7AActin-like protein 7A; Belongs to the actin family. (435 aa)
ACTL7BActin-like protein 7B; Belongs to the actin family. (415 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
CK820_G0053598POTEJ isoform 1; Belongs to the actin family. (1078 aa)
EPHA1EPH receptor A1. (976 aa)
EPHB6Ephrin type-B receptor 6; Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity). (1020 aa)
EPHB4EPH receptor B4. (987 aa)
PSENENT0105581 isoform 1. (101 aa)
ENSPTRP00000016618Actin beta like 2. (375 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)
AP2A2AP2A2 isoform 4. (380 aa)
EFNA1EFNA1 isoform 2; Belongs to the ephrin family. (205 aa)
EFNA3Ephrin-A3 isoform X1. (238 aa)
EFNA4EFNA4 isoform 1; Belongs to the ephrin family. (201 aa)
EPHA10EPH receptor A10. (1014 aa)
EPHA8EPHA8 isoform 1. (997 aa)
EPHA2EPH receptor A2. (976 aa)
ACTRT2ACTRT2 isoform 1; Belongs to the actin family. (377 aa)
EPHA7EPHA7 isoform 2. (998 aa)
EFNA5EFNA5 isoform 1; Belongs to the ephrin family. (228 aa)
EPHA5EPH receptor A5. (1038 aa)
EPHA6EPH receptor A6. (1130 aa)
EPHA3EPH receptor A3. (983 aa)
TIAM1T-cell lymphoma invasion and metastasis 1. (1591 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
NCSTNNCSTN isoform 1. (721 aa)
ENSPTRP00000093517annotation not available (149 aa)
YES1Tyrosine-protein kinase. (558 aa)
EPHA1-2EPH receptor A1. (976 aa)
VAV3VAV3 isoform 2. (927 aa)
EFNB1EFNB1 isoform 1; Belongs to the ephrin family. (346 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
EFNB3EFNB3 isoform 1; Belongs to the ephrin family. (340 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
DNM1-2Dynamin 1. (867 aa)
EPHA4EPH receptor A4. (986 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
MMP9Matrix metallopeptidase 9. (699 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
DNM1DNM1 isoform 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSPTRP00000081537annotation not available (449 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
ENSPTRP00000080740annotation not available (150 aa)
ACTG1ACTG1 isoform 13. (375 aa)
CK820_G0023066ACTA1 isoform 2. (150 aa)
AP2M1AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family. (459 aa)
EPHB4-2EPH receptor B4. (987 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSPTRP00000076988annotation not available (871 aa)
SRCTyrosine-protein kinase. (542 aa)
CLTCL1CLTCL1 isoform 5. (1510 aa)
EPHB3EPHB3 isoform 1. (1031 aa)
ENSPTRP00000070878annotation not available (324 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
LOC736439AP-2 complex subunit beta pseudogene. (893 aa)
ENSPTRP00000064849annotation not available (150 aa)
ACTL9ACTL9 isoform 1; Belongs to the actin family. (416 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
EPHB1EPH receptor B1. (984 aa)
EPHB2EPH receptor B2. (1055 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (485 aa)
EFNA2EFNA2 isoform 1; Belongs to the ephrin family. (190 aa)
ELSPBP1ELSPBP1 isoform 6. (219 aa)
LYNTyrosine-protein kinase. (512 aa)
LOC744297POTE ankyrin domain family member G-like. (956 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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