STRINGSTRING
MYH7B MYH7B NPPA NPPA NPPB NPPB MAST2 MAST2 HIPK1 HIPK1 CASQ2 CASQ2 TMOD4 TMOD4 NPR1 NPR1 ATP1A4 ATP1A4 CASQ1 CASQ1 ATP1B1 ATP1B1 TNNI1 TNNI1 LMOD1 LMOD1 ACTA1 ACTA1 VIM VIM FXYD4 FXYD4 VCL VCL MYOF MYOF KCNK18 KCNK18 MYBPC3 MYBPC3 KCNK4 KCNK4 KCNK7 KCNK7 PAK1 PAK1 LOC466793 LOC466793 SCN3B SCN3B CACNA1C CACNA1C KCNA5 KCNA5 ATP2A2 ATP2A2 ORAI1 ORAI1 FGF14 FGF14 KCNK10 KCNK10 KCNK13 KCNK13 ACTC1 ACTC1 TMOD3 TMOD3 TLN2 TLN2 CACNA1H CACNA1H ASPHD1 ASPHD1 MYLPF MYLPF TRIM72 TRIM72 RANGRF RANGRF RNF222 RNF222 MYH13 MYH13 MYH1 MYH1 MYH1-2 MYH1-2 TCAP TCAP SCN4A SCN4A CACNG5 CACNG5 KCNJ2 KCNJ2 MYL12B MYL12B MAST1 MAST1 PRKACA PRKACA MAST3 MAST3 FXYD1 FXYD1 KCNK6 KCNK6 CALM3 CALM3 KCNJ14 KCNJ14 CACNG7 CACNG7 CACNG6 CACNG6 FKBP1B FKBP1B KCNIP3 KCNIP3 FAHD2A FAHD2A ENSPTRP00000020997 ENSPTRP00000020997 SCN1A SCN1A SCN9A SCN9A TTN TTN MYL1 MYL1 KCNE4 KCNE4 NPPC NPPC MYL9 MYL9 KCNK15 KCNK15 KCNE1 KCNE1 ITPR2 ITPR2 ITPR1 ITPR1 CAV3 CAV3 KAT2B KAT2B SCN11A SCN11A MYL3 MYL3 TNNC1 TNNC1 LMOD3 LMOD3 MYH15 MYH15 ATP1B3 ATP1B3 PAK2 PAK2 SMIM20 SMIM20 CORIN CORIN GUCY1A1 GUCY1A1 SORBS2 SORBS2 ITGA1 ITGA1 NKX2-5 NKX2-5 ITPR3 ITPR3 KCNK17 KCNK17 KCNK16 KCNK16 MYL7 MYL7 MYL10 MYL10 HIPK2 HIPK2 SORBS3 SORBS3 CK820_G0008402 CK820_G0008402 NPR2 NPR2 PHEX PHEX KCND1 KCND1 KCNK5 KCNK5 TMOD1 TMOD1 TPM4 TPM4 TPM1 TPM1 SCN7A SCN7A SCN8A SCN8A SCN10A SCN10A PDE5A PDE5A ATP2A3 ATP2A3 ATP2B1 ATP2B1 WWTR1 WWTR1 CES1 CES1 CACNB2 CACNB2 MYL4 MYL4 FXYD6 FXYD6 KCNIP4 KCNIP4 DNAAF3 DNAAF3 CLIC2 CLIC2 KCNH2 KCNH2 LMOD2 LMOD2 AKAP9 AKAP9 KCNJ11 KCNJ11 TNNI3 TNNI3 CACNG8 CACNG8 ANXA1 ANXA1 ITGB5 ITGB5 TNNC2 TNNC2 MYH4 MYH4 ATP1B2 ATP1B2 ASPH ASPH SDR42E2 SDR42E2 KCNE2 KCNE2 SCN3A SCN3A ASPHD2 ASPHD2 DYSF DYSF KCNK2 KCNK2 CACNA1I CACNA1I TRDN TRDN ENSPTRP00000059986 ENSPTRP00000059986 KCNE5 KCNE5 KCND3 KCND3 KCNE3 KCNE3 ENSPTRP00000062109 ENSPTRP00000062109 ENSPTRP00000062239 ENSPTRP00000062239 MAST4 MAST4 ENSPTRP00000063164 ENSPTRP00000063164 TNNT1 TNNT1 GUCY1B1 GUCY1B1 MYH11 MYH11 SLC8A1 SLC8A1 LOC452727 LOC452727 MYL12A MYL12A RYR2 RYR2 ENSPTRP00000064617 ENSPTRP00000064617 AKAP9-2 AKAP9-2 CK820_G0045217 CK820_G0045217 CLIC2-2 CLIC2-2 ENSPTRP00000065799 ENSPTRP00000065799 CACNA1G CACNA1G ENSPTRP00000066121 ENSPTRP00000066121 AHCYL1 AHCYL1 CK820_G0008402-2 CK820_G0008402-2 MYBPC2 MYBPC2 TNNI2 TNNI2 FXYD5 FXYD5 FGF13 FGF13 ENSPTRP00000067815 ENSPTRP00000067815 KCNIP2 KCNIP2 SPEGNB SPEGNB DMPK DMPK ATP2B3 ATP2B3 KCND2 KCND2 ATP1A3 ATP1A3 LOC101058464 LOC101058464 ENSPTRP00000068927 ENSPTRP00000068927 TBX5 TBX5 ENSPTRP00000069052 ENSPTRP00000069052 ATP2B4 ATP2B4 SCN5A SCN5A DMD DMD ORAI2-2 ORAI2-2 GATD1 GATD1 TPM2 TPM2 PXN PXN ACTL10-2 ACTL10-2 TNNT2 TNNT2 TLN1 TLN1 CACNA2D1 CACNA2D1 MYH3 MYH3 KCNK12 KCNK12 SCN2B SCN2B NEB NEB FER1L5 FER1L5 CAMK2B CAMK2B KCNJ4 KCNJ4 TNNT3 TNNT3 GUCY1A2 GUCY1A2 MYL6B MYL6B SCN2A SCN2A ENSPTRP00000074981 ENSPTRP00000074981 CK820_G0026206 CK820_G0026206 PXN-2 PXN-2 STIM2 STIM2 CK820_G0026206-2 CK820_G0026206-2 GATA4 GATA4 PLN PLN FXYD7 FXYD7 MYL10-2 MYL10-2 STIM1 STIM1 CACNG4 CACNG4 ORAI3 ORAI3 ENSPTRP00000078278 ENSPTRP00000078278 ORAI2 ORAI2 ENSPTRP00000078400 ENSPTRP00000078400 TGFB1I1 TGFB1I1 MYL2 MYL2 FXYD3 FXYD3 KCNJ12 KCNJ12 ACTN2 ACTN2 CAMK2A CAMK2A SRI SRI MMEL1 MMEL1 ANXA6 ANXA6 SRI-2 SRI-2 MYH7 MYH7 ATP1A2 ATP1A2 DES DES ATP2A1 ATP2A1 TRPC1 TRPC1 ENSPTRP00000083926 ENSPTRP00000083926 ACTG2 ACTG2 TPM3 TPM3 CALD1 CALD1 ANXA2 ANXA2 ABCC9 ABCC9 DMD-2 DMD-2 KCNK3 KCNK3 ENSPTRP00000085289 ENSPTRP00000085289 ENSPTRP00000085680 ENSPTRP00000085680 FAHD2B FAHD2B KCNK1 KCNK1 ACTN3 ACTN3 SLN SLN CACNB1 CACNB1 ATP2B2 ATP2B2 ENSPTRP00000086934 ENSPTRP00000086934 CK820_G0056661 CK820_G0056661 MYBPC1 MYBPC1 SORBS1 SORBS1 KCNQ1 KCNQ1 CAMK2D CAMK2D KCNIP1 KCNIP1 MYH6 MYH6 MYL6 MYL6 CACNA2D2 CACNA2D2 MYLK MYLK FGF11 FGF11 SCN1B SCN1B FGF12 FGF12 ATP1A1 ATP1A1 ACTL10 ACTL10 ALDH2 ALDH2 MME MME SLC8A3 SLC8A3 CK820_G0030361 CK820_G0030361 RYR3 RYR3 ENSPTRP00000091063 ENSPTRP00000091063 SCN4B SCN4B TMOD2 TMOD2 ENSPTRP00000091918 ENSPTRP00000091918 NOS1 NOS1 LOC460237 LOC460237 LPXN LPXN RYR1 RYR1 CK820_G0029100 CK820_G0029100 MYL5 MYL5 CAMK2G CAMK2G KCNK9 KCNK9 LOC468314 LOC468314 SLC8A2 SLC8A2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
NPPANatriuretic peptide A. (153 aa)
NPPBNatriuretic peptide B. (134 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1798 aa)
HIPK1HIPK1 isoform 10. (1210 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
TMOD4TMOD4 isoform 2. (345 aa)
NPR1Guanylate cyclase. (1061 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (396 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (By similarity). (303 aa)
TNNI1Troponin I type 1 (Skeletal, slow). (187 aa)
LMOD1LMOD1 isoform 2. (600 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
VIMVimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
VCLVCL isoform 2. (1134 aa)
MYOFMYOF isoform 3. (2061 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa)
MYBPC3Myosin binding protein C, cardiac. (1274 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (393 aa)
KCNK7Potassium channel subfamily K member. (307 aa)
PAK1Non-specific serine/threonine protein kinase. (553 aa)
LOC466793FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ORAI1ORAI1 isoform 1. (301 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (408 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
TMOD3Tropomodulin 3 (Ubiquitous). (352 aa)
TLN2TLN2 isoform 1. (2544 aa)
CACNA1HCACNA1H isoform 1. (2240 aa)
ASPHD1Aspartate beta-hydroxylase domain containing 1. (390 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (169 aa)
TRIM72Tripartite motif containing 72. (477 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
RNF222Ring finger protein 222. (220 aa)
MYH13MYH13 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1888 aa)
MYH1MYH8 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
MYH1-2MYH1 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
TCAPTCAP isoform 1. (167 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
KCNJ2Potassium inwardly-rectifying channel, subfamily J, member 2. (427 aa)
MYL12BMyosin light chain 12B. (172 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1570 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
MAST3MAST3 isoform 1. (1227 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (81 aa)
KCNK6Potassium channel subfamily K member. (313 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
FAHD2AFumarylacetoacetate hydrolase domain containing 2A. (314 aa)
ENSPTRP00000020997LOW QUALITY PROTEIN: fumarylacetoacetate hydrolase domain-containing protein 2A-like. (314 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1988 aa)
TTNTTN isoform 3. (32000 aa)
MYL1Myosin light chain 1. (192 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (221 aa)
NPPCNatriuretic peptide C. (126 aa)
MYL9Myosin, light chain 9, regulatory. (172 aa)
KCNK15Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (330 aa)
KCNE1KCNE1B isoform 1. (132 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor, type 2. (2727 aa)
ITPR1ITPR1 isoform 3. (2700 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1792 aa)
MYL3Myosin, light chain 3, alkali ventricular, skeletal, slow. (224 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
LMOD3LMOD3 isoform 1. (560 aa)
MYH15MYH15 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1946 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
PAK2Non-specific serine/threonine protein kinase. (476 aa)
SMIM20SMIM20 isoform 1. (168 aa)
CORINCorin, serine peptidase. (1042 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
NKX2-5NKX2-5 isoform 1. (325 aa)
ITPR3ITPR3 isoform 1. (2677 aa)
KCNK17Potassium channel subfamily K member. (332 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (309 aa)
MYL7Myosin light chain 7. (175 aa)
MYL10ADCY7 isoform 13. (226 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
CK820_G0008402Annexin. (233 aa)
NPR2Guanylate cyclase. (1047 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
TMOD1TMOD1 isoform 1. (359 aa)
TPM4TPM4 isoform 4; Belongs to the tropomyosin family. (239 aa)
TPM1TPM1 isoform 3; Belongs to the tropomyosin family. (326 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1682 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
PDE5APhosphodiesterase. (875 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
CES1Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (537 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
MYL4Myosin, light chain 4, alkali atrial, embryonic. (193 aa)
FXYD6FXYD domain-containing ion transport regulator 6 precursor. (95 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (250 aa)
DNAAF3Dynein axonemal assembly factor 3. (487 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
LMOD2LMOD2 isoform 1. (548 aa)
AKAP9A kinase (PRKA) anchor protein (Yotiao) 9. (3908 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
TNNI3TNNI3 isoform 2. (169 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (427 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...] (346 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
TNNC2Troponin C2, fast skeletal type. (160 aa)
MYH4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ASPHASPH isoform 1. (762 aa)
SDR42E2Short chain dehydrogenase/reductase family 42E, member 2. (422 aa)
KCNE2KCNE2 isoform 1. (123 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (369 aa)
DYSFDYSF isoform 8. (2119 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2223 aa)
TRDNTRDN isoform 1. (730 aa)
ENSPTRP00000059986annotation not available (209 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
KCND3Potassium voltage-gated channel, Shal-related subfamily, member 3; Belongs to the potassium channel family. (655 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
ENSPTRP00000062109annotation not available (93 aa)
ENSPTRP00000062239annotation not available (93 aa)
MAST4MAST4 isoform 1. (2623 aa)
ENSPTRP00000063164annotation not available (1061 aa)
TNNT1Troponin T1, slow skeletal type. (278 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (644 aa)
MYH11MYH11 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
LOC452727Guanylate cyclase soluble subunit beta-2. (664 aa)
MYL12AMyosin light chain 12A. (177 aa)
RYR2RYR2 isoform 1. (4941 aa)
ENSPTRP00000064617annotation not available (92 aa)
AKAP9-2A-kinase anchoring protein 9. (3896 aa)
CK820_G0045217TPM3 isoform 8; Belongs to the tropomyosin family. (245 aa)
CLIC2-2Chloride intracellular channel 2. (247 aa)
ENSPTRP00000065799annotation not available (264 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
ENSPTRP00000066121annotation not available (305 aa)
AHCYL1Adenosylhomocysteinase. (499 aa)
CK820_G0008402-2Annexin. (325 aa)
MYBPC2MYBPC2 isoform 1. (1143 aa)
TNNI2Troponin I type 2 (Skeletal, fast). (179 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (194 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ENSPTRP00000067815annotation not available (246 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
SPEGNBSPEG isoform 3. (238 aa)
DMPKDystrophia myotonica-protein kinase. (639 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
KCND2Potassium voltage-gated channel, Shal-related subfamily, member 2; Belongs to the potassium channel family. (630 aa)
ATP1A3ATP1A3 isoform 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1287 aa)
LOC101058464TPM3 isoform 13; Belongs to the tropomyosin family. (245 aa)
ENSPTRP00000068927annotation not available (480 aa)
TBX5T-box transcription factor 5. (518 aa)
ENSPTRP00000069052annotation not available (151 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
DMDDMD isoform 3. (3685 aa)
ORAI2-2ORAI calcium release-activated calcium modulator 2. (262 aa)
GATD1Glutamine amidotransferase like class 1 domain containing 1. (220 aa)
TPM2TPM2 isoform 3; Belongs to the tropomyosin family. (284 aa)
PXNPXN isoform 20. (1078 aa)
ACTL10-2Chromosome 20 open reading frame 134; Belongs to the actin family. (245 aa)
TNNT2Troponin T type 2 (Cardiac). (298 aa)
TLN1TLN1 isoform 1. (2558 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
MYH3Myosin, heavy chain 3, skeletal muscle, embryonic; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (430 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
NEBNEB isoform 5. (8417 aa)
FER1L5FER1L5 isoform 5. (1974 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
TNNT3Troponin T3, fast skeletal type. (269 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (765 aa)
MYL6BMyosin light chain 6B. (210 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
ENSPTRP00000074981annotation not available (80 aa)
CK820_G0026206TPM4 isoform 9. (233 aa)
PXN-2PXN isoform 9. (1081 aa)
STIM2STIM2 isoform 3. (841 aa)
CK820_G0026206-2TPM4 isoform 13. (206 aa)
GATA4GATA binding protein 4. (443 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (117 aa)
MYL10-2MYL10 isoform 1. (226 aa)
STIM1Stromal interaction molecule 1. (791 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
ENSPTRP00000078278annotation not available (260 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
ENSPTRP00000078400annotation not available (305 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
MYL2Myosin, light chain 2, regulatory, cardiac, slow. (166 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (143 aa)
KCNJ12Potassium inwardly-rectifying channel, subfamily J, member 12. (433 aa)
ACTN2ACTN2 isoform 2. (894 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
SRISRI isoform 1. (205 aa)
MMEL1Membrane metalloendopeptidase like 1. (779 aa)
ANXA6Annexin. (788 aa)
SRI-2SRI isoform 5. (237 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
DESDES isoform 1; Belongs to the intermediate filament family. (518 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1068 aa)
TRPC1TRPC1 isoform 3; Belongs to the transient receptor (TC 1.A.4) family. (795 aa)
ENSPTRP00000083926annotation not available (290 aa)
ACTG2ACTG2 isoform 7; Belongs to the actin family. (401 aa)
TPM3TPM3 isoform 3; Belongs to the tropomyosin family. (285 aa)
CALD1CALD1 isoform 8. (793 aa)
ANXA2Annexin. (357 aa)
ABCC9ATP-binding cassette, sub-family C (CFTR/MRP), member 9. (1549 aa)
DMD-2Dystrophin. (643 aa)
KCNK3Potassium channel subfamily K member. (394 aa)
ENSPTRP00000085289annotation not available (322 aa)
ENSPTRP00000085680annotation not available (88 aa)
FAHD2BFumarylacetoacetate hydrolase domain containing 2B. (343 aa)
KCNK1Potassium channel subfamily K member. (337 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (944 aa)
SLNSLN isoform 1. (31 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ENSPTRP00000086934annotation not available (467 aa)
CK820_G0056661KCNJ18 isoform 1. (433 aa)
MYBPC1Myosin binding protein C, slow type. (1173 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (241 aa)
MYH6MYH6 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
MYL6MYL6 isoform 8. (233 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1156 aa)
MYLKMYLK isoform 12. (1919 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
SCN1BSodium channel subunit beta-1; Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A. (268 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ACTL10Actin like 10. (245 aa)
ALDH2T0055793 isoform 1. (517 aa)
MMEMembrane metallo-endopeptidase. (750 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
CK820_G0030361RYR1 isoform 5. (4901 aa)
RYR3Ryanodine receptor 3. (4873 aa)
ENSPTRP00000091063annotation not available (314 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
TMOD2Tropomodulin 2 (Neuronal). (351 aa)
ENSPTRP00000091918annotation not available (454 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
LOC460237TPM4 isoform 1; Belongs to the tropomyosin family. (241 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa)
RYR1RYR1 isoform 3. (5037 aa)
CK820_G0029100SRI isoform 2. (98 aa)
MYL5Myosin light chain 5. (173 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (562 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
LOC468314MYL6 isoform 18. (116 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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