STRINGSTRING
AKT3 AKT3 PLCB3 PLCB3 GNB2 GNB2 PIK3R6 PIK3R6 AKT1 AKT1 ENSPTRP00000081694 ENSPTRP00000081694 CDC42 CDC42 PDPK1 PDPK1 GNB2-2 GNB2-2 ENSPTRP00000072507 ENSPTRP00000072507 ENSPTRP00000071036 ENSPTRP00000071036 GNG7 GNG7 GNG4 GNG4 ENSPTRP00000093443 ENSPTRP00000093443 CK820_G0040666 CK820_G0040666 GNG3 GNG3 PAK1 PAK1 PLCB2 PLCB2 GNB5 GNB5 MFSD6L MFSD6L PIK3R5 PIK3R5 MFSD6 MFSD6 PLCB1 PLCB1 RHOA RHOA GNB4 GNB4 GNGT1 GNGT1 GNG11 GNG11 GNG10 GNG10 BTK BTK ARHGEF6 ARHGEF6 PIK3CG PIK3CG GNB3 GNB3 GNGT2 GNGT2 GNG2 GNG2 GNB1 GNB1 GNG13 GNG13 GNG12 GNG12 ENSPTRP00000066583 ENSPTRP00000066583 GNG8 GNG8 AKT2 AKT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
GNB2Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
AKT1AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa)
ENSPTRP00000081694annotation not available (182 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
GNB2-2G protein subunit beta 2. (372 aa)
ENSPTRP00000072507annotation not available (659 aa)
ENSPTRP00000071036annotation not available (68 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSPTRP00000093443annotation not available (57 aa)
CK820_G0040666Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PAK1Non-specific serine/threonine protein kinase. (553 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GNB5GNB5 isoform 1. (409 aa)
MFSD6LMajor facilitator superfamily domain containing 6 like. (586 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (882 aa)
MFSD6Major facilitator superfamily domain containing 6. (791 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
RHOARas homolog family member A. (193 aa)
GNB4Guanine nucleotide binding protein (G protein), beta polypeptide 4. (340 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG10Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10. (68 aa)
BTKBTK isoform 2. (693 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (783 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
GNB3G protein subunit beta 3. (340 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GNB1Guanine nucleotide binding protein (G protein), beta polypeptide 1. (340 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSPTRP00000066583annotation not available (181 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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