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CACNA1H CACNA1H NRTN NRTN COL5A3 COL5A3 COL3A1 COL3A1 COL4A3 COL4A3 COL6A3 COL6A3 GFRA4 GFRA4 COL9A3 COL9A3 COL6A2 COL6A2 COL6A6 COL6A6 COL6A5 COL6A5 GFRA2 GFRA2 AGRN AGRN COL2A1 COL2A1 CACNB2 CACNB2 COL4A4 COL4A4 COL5A2 COL5A2 CACNB4 CACNB4 CACNA1I CACNA1I COL4A2 COL4A2 NCAM1 NCAM1 CACNA1G CACNA1G COL4A5 COL4A5 PSPN PSPN NCAM2 NCAM2 COL5A1 COL5A1 CACNA1S CACNA1S PRNP PRNP CACNA1D CACNA1D COL9A2 COL9A2 ST8SIA2 ST8SIA2 ARTN ARTN CNTN2 CNTN2 CACNB1 CACNB1 CACNB3 CACNB3 GFRA1 GFRA1 ENSPTRP00000089337 ENSPTRP00000089337 COL4A1 COL4A1 CK820_G0023028 CK820_G0023028 ST8SIA4 ST8SIA4 COL9A1 COL9A1 CACNA1C CACNA1C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNA1HCACNA1H isoform 1. (2240 aa)
NRTNNRTN isoform 1. (197 aa)
COL5A3Collagen type V alpha 3 chain. (1745 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL4A3Collagen type IV alpha 3 chain. (1670 aa)
COL6A3COL6A3 isoform 2. (3177 aa)
GFRA4GFRA4 isoform 1. (269 aa)
COL9A3Collagen type IX alpha 3 chain. (684 aa)
COL6A2COL6A2 isoform 4. (444 aa)
COL6A6Collagen, type VI, alpha 6. (2263 aa)
COL6A5COL6A5 isoform 2. (2625 aa)
GFRA2GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (464 aa)
AGRNAGRN isoform 2. (2066 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
COL4A4COL4A4 isoform 1. (1690 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2223 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
NCAM1Neural cell adhesion molecule 1. (884 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
COL4A5Collagen type IV alpha 5 chain. (1691 aa)
PSPNPSPN isoform 2. (156 aa)
NCAM2Neural cell adhesion molecule 2. (862 aa)
COL5A1Collagen type V alpha 1 chain. (1841 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
COL9A2Collagen type IX alpha 2 chain. (689 aa)
ST8SIA2Alpha-2,8-sialyltransferase 8B; May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression. (375 aa)
ARTNARTN isoform 11. (235 aa)
CNTN2CNTN2 isoform 13. (1040 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (626 aa)
CACNB3Calcium channel, voltage-dependent, beta 3 subunit. (487 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa)
ENSPTRP00000089337annotation not available (2012 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
CK820_G0023028COL6A2 isoform 1. (417 aa)
ST8SIA4CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. (359 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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