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GRIA1 GRIA1 CAMKK1 CAMKK1 CAMK2G CAMK2G ENSPTRP00000093238 ENSPTRP00000093238 PRKAG1 PRKAG1 THAP6 THAP6 DLG2 DLG2 CK820_G0053542-2 CK820_G0053542-2 PDPK1 PDPK1 ENSPTRP00000090121 ENSPTRP00000090121 PRKAG2 PRKAG2 ENSPTRP00000089644 ENSPTRP00000089644 CAMK2D CAMK2D ENSPTRP00000088253 ENSPTRP00000088253 LOC750209 LOC750209 CK820_G0045118 CK820_G0045118 ENSPTRP00000086254 ENSPTRP00000086254 CAMK1 CAMK1 KRAS KRAS ENSPTRP00000084437 ENSPTRP00000084437 RAC1-2 RAC1-2 LOC738663 LOC738663 ENSPTRP00000083779 ENSPTRP00000083779 CK820_G0051601 CK820_G0051601 DCLK1 DCLK1 RPS6KA3 RPS6KA3 PEX26-2 PEX26-2 CAMK2A CAMK2A ACTN2 ACTN2 PRKAB2 PRKAB2 PRKAG2-2 PRKAG2-2 RASGRF1 RASGRF1 ADCY8 ADCY8 SRC SRC NEFL NEFL ENSPTRP00000074829 ENSPTRP00000074829 TUBA4B TUBA4B CAMK2B CAMK2B RPS6KA6 RPS6KA6 CREB1 CREB1 GRIN2C GRIN2C ENSPTRP00000071983 ENSPTRP00000071983 TUBA1C TUBA1C PNCK PNCK PRKX PRKX DLG3 DLG3 KPNA2 KPNA2 PRKAR1B PRKAR1B RAC1 RAC1 ENSPTRP00000067784 ENSPTRP00000067784 DLG1 DLG1 TUBA1B TUBA1B ENSPTRP00000065686 ENSPTRP00000065686 ADCY1-2 ADCY1-2 ERAS ERAS GRIN2D GRIN2D ENSPTRP00000063748 ENSPTRP00000063748 ERBB4 ERBB4 RPS6KA2 RPS6KA2 TUBA3E TUBA3E ARHGEF7 ARHGEF7 PRKY PRKY TUBB4A TUBB4A PRKAR2B PRKAR2B GIT1 GIT1 ENSPTRP00000056983 ENSPTRP00000056983 GRIN2A GRIN2A TUBB6 TUBB6 MAPK3 MAPK3 TUBB8 TUBB8 PRKAA1 PRKAA1 PRKAR1A PRKAR1A STK33 STK33 PRKACB PRKACB GRIN1 GRIN1 TUBA3C TUBA3C PRKACG PRKACG ADCY1 ADCY1 TUBB4B TUBB4B CAMK4 CAMK4 RASGRF2 RASGRF2 GRIA2 GRIA2 CAMKV CAMKV MAPK1 MAPK1 THAP7 THAP7 PEX26 PEX26 TUBB1 TUBB1 CNBD2 CNBD2 TUBA4A TUBA4A PRKAG3 PRKAG3 LOC107973630 LOC107973630 CALM3 CALM3 PRKACA PRKACA MAPT MAPT DLG4 DLG4 PSKH1 PSKH1 PRKAR2A PRKAR2A PNCK-2 PNCK-2 NRG1 NRG1 ENSPTRP00000008373 ENSPTRP00000008373 TUBA1A TUBA1A PRKAB1 PRKAB1 PRKAA2 PRKAA2 LRRC7 LRRC7 NRAS NRAS CAMK1G CAMK1G CAMKK2 CAMKK2 CK820_G0053542 CK820_G0053542 TUBAL3 TUBAL3 CAMK1D CAMK1D HRAS HRAS NRGN NRGN GRIN2B GRIN2B ENSPTRP00000091139 ENSPTRP00000091139 RPS6KA1 RPS6KA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (532 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (562 aa)
ENSPTRP00000093238Tubulin beta-8 chain-like. (439 aa)
PRKAG1PRKAG1 isoform 12. (333 aa)
THAP6THAP domain containing 6. (222 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
CK820_G0053542-2TUBB8 isoform 4. (119 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
ENSPTRP00000090121annotation not available (331 aa)
PRKAG2PRKAG2 isoform 4. (445 aa)
ENSPTRP00000089644annotation not available (335 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
ENSPTRP00000088253annotation not available (118 aa)
LOC750209Tubulin beta-8 chain isoform X2. (435 aa)
CK820_G0045118TUBB4A isoform 4; Belongs to the tubulin family. (407 aa)
ENSPTRP00000086254Microtubule-associated protein tau. (776 aa)
CAMK1Calcium/calmodulin-dependent protein kinase I; Belongs to the protein kinase superfamily. (380 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
ENSPTRP00000084437annotation not available (441 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
LOC738663Tubulin beta-8 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Has a key role in meiotic spindle assembly and oocyte maturation (By similarity); Belongs to the tubulin family. (444 aa)
ENSPTRP00000083779annotation not available (309 aa)
CK820_G0051601TUBB3 isoform 13. (122 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
PEX26-2Peroxisomal biogenesis factor 26. (454 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ACTN2ACTN2 isoform 2. (894 aa)
PRKAB2Protein kinase, AMP-activated, beta 2 non-catalytic subunit. (272 aa)
PRKAG2-2PRKAG2 isoform 10. (204 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
SRCTyrosine-protein kinase. (542 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
ENSPTRP00000074829annotation not available (385 aa)
TUBA4BTUBA4B isoform 1. (241 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GRIN2CGRIN2C isoform 4. (1240 aa)
ENSPTRP00000071983annotation not available (346 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (519 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (426 aa)
PRKXProtein kinase, X-linked; Belongs to the protein kinase superfamily. (358 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (853 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
ENSPTRP00000067784annotation not available (357 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (458 aa)
ENSPTRP00000065686annotation not available (506 aa)
ADCY1-2Adenylate cyclase 1. (1119 aa)
ERASES cell expressed Ras. (233 aa)
GRIN2DGRIN2D isoform 1. (1265 aa)
ENSPTRP00000063748annotation not available (459 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
RPS6KA2Ribosomal protein S6 kinase alpha-2 isoform X1. (758 aa)
TUBA3ETubulin, alpha 3e. (459 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
PRKYSerine/threonine-protein kinase PRKX. (358 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
PRKAR2BProtein kinase, cAMP-dependent, regulatory, type II, beta. (418 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
ENSPTRP00000056983annotation not available (477 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...] (1471 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (548 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TUBB8Tubulin beta chain-like. (424 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PRKAR1AProtein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1). (381 aa)
STK33Serine/threonine kinase 33. (514 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GRIN1Glutamate receptor, ionotropic, N-methyl D-aspartate 1. (845 aa)
TUBA3CTubulin alpha 3c. (450 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (547 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
CAMKVCaM kinase like vesicle associated. (501 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
THAP7THAP domain containing 7. (309 aa)
PEX26Tubulin alpha-8 chain. (454 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CNBD2CNBD2 isoform 3. (511 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PRKAG3PRKAG3 isoform 1. (489 aa)
LOC107973630Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
MAPTMicrotubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] (776 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
PNCK-2Calcium/calmodulin-dependent protein kinase type 1B isoform X4. (343 aa)
NRG1NRG1 isoform 3. (713 aa)
ENSPTRP00000008373annotation not available (448 aa)
TUBA1ADetyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). (451 aa)
PRKAB1Protein kinase, AMP-activated, beta 1 non-catalytic subunit. (270 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
LRRC7LRRC7 isoform 11. (1542 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2, beta. (588 aa)
CK820_G0053542TUBB8 isoform 7. (435 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
NRGNNRGN isoform 1. (78 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ENSPTRP00000091139annotation not available (114 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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