STRINGSTRING
DLG2 DLG2 KIF17 KIF17 PRKAA2 PRKAA2 LRRC7 LRRC7 NRAS NRAS CAMK1G CAMK1G CK820_G0053542 CK820_G0053542 TUBAL3 TUBAL3 CAMK1D CAMK1D INA INA HRAS HRAS NRGN NRGN GRIN2B GRIN2B ENSPTRP00000008373 ENSPTRP00000008373 TUBA1A TUBA1A LIN7A LIN7A PRKAB1 PRKAB1 CAMKK2 CAMKK2 PSKH1 PSKH1 DLG4 DLG4 MAPT MAPT PRKACA PRKACA CALM3 CALM3 LIN7B LIN7B LOC107973630 LOC107973630 PRKAG3 PRKAG3 TUBA4A TUBA4A CNBD2 CNBD2 TUBB1 TUBB1 PEX26 PEX26 THAP7 THAP7 MAPK1 MAPK1 PPM1F PPM1F CAMKV CAMKV GRIA2 GRIA2 RASGRF2 RASGRF2 CAMK4 CAMK4 TUBB4B TUBB4B ADCY1 ADCY1 PRKACG PRKACG APBA1 APBA1 TUBA3C TUBA3C GRIN3A GRIN3A LIN7C LIN7C GRIN1 GRIN1 PRKACB PRKACB PPM1E PPM1E STK33 STK33 PRKAR1A PRKAR1A LRBA LRBA CASK CASK PRKAA1 PRKAA1 GRIN3B GRIN3B TUBB8 TUBB8 MAPK3 MAPK3 TUBB6 TUBB6 GRIN2A GRIN2A ENSPTRP00000056983 ENSPTRP00000056983 GIT1 GIT1 PRKAR2B PRKAR2B TUBB4A TUBB4A PRKY PRKY ARHGEF7 ARHGEF7 TUBA3E TUBA3E RPS6KA2 RPS6KA2 ERBB4 ERBB4 ENSPTRP00000063748 ENSPTRP00000063748 GRIN2D GRIN2D ERAS ERAS ADCY1-2 ADCY1-2 ENSPTRP00000065686 ENSPTRP00000065686 TUBA1B TUBA1B DLG1 DLG1 ENSPTRP00000067784 ENSPTRP00000067784 RAC1 RAC1 PRKAR1B PRKAR1B KPNA2 KPNA2 DLG3 DLG3 PRKX PRKX PNCK PNCK ENSPTRP00000071372 ENSPTRP00000071372 TUBA1C TUBA1C ENSPTRP00000071983 ENSPTRP00000071983 GRIN2C GRIN2C NBEA NBEA CREB1 CREB1 RPS6KA6 RPS6KA6 CAMK2B CAMK2B NEFM NEFM TUBA4B TUBA4B ENSPTRP00000074829 ENSPTRP00000074829 CK820_G0016908 CK820_G0016908 GRIA3 GRIA3 NEFL NEFL SRC SRC DCLK3 DCLK3 ADCY8 ADCY8 PAPLN PAPLN RASGRF1 RASGRF1 PRKAG2-2 PRKAG2-2 PRKAB2 PRKAB2 ACTN2 ACTN2 CAMK2A CAMK2A PEX26-2 PEX26-2 RPS6KA3 RPS6KA3 DCLK1 DCLK1 CK820_G0051601 CK820_G0051601 ENSPTRP00000083779 ENSPTRP00000083779 LOC738663 LOC738663 GRIA4 GRIA4 RAC1-2 RAC1-2 ENSPTRP00000084386 ENSPTRP00000084386 ENSPTRP00000084437 ENSPTRP00000084437 KRAS KRAS CAMK1 CAMK1 ENSPTRP00000086254 ENSPTRP00000086254 CK820_G0045118 CK820_G0045118 LOC750209 LOC750209 ENSPTRP00000088150 ENSPTRP00000088150 ENSPTRP00000088253 ENSPTRP00000088253 CAMK2D CAMK2D ENSPTRP00000089644 ENSPTRP00000089644 PRKAG2 PRKAG2 ENSPTRP00000090121 ENSPTRP00000090121 PDPK1 PDPK1 CK820_G0053542-2 CK820_G0053542-2 RPS6KA1 RPS6KA1 ENSPTRP00000091139 ENSPTRP00000091139 PRKAR2A PRKAR2A PNCK-2 PNCK-2 GRIA1 GRIA1 NRG1 NRG1 CAMKK1 CAMKK1 CAMK2G CAMK2G ENSPTRP00000093238 ENSPTRP00000093238 PRKAG1 PRKAG1 THAP6 THAP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
KIF17KIF17 isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
LRRC7LRRC7 isoform 11. (1542 aa)
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
CK820_G0053542TUBB8 isoform 7. (435 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
INAInternexin neuronal intermediate filament protein, alpha; Belongs to the intermediate filament family. (499 aa)
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)
NRGNNRGN isoform 1. (78 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ENSPTRP00000008373annotation not available (448 aa)
TUBA1ADetyrosinated tubulin alpha-1A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). (451 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
PRKAB1Protein kinase, AMP-activated, beta 1 non-catalytic subunit. (270 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2, beta. (588 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
MAPTMicrotubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabili [...] (776 aa)
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)
CALM3Calmodulin 1 (Phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
LOC107973630Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
PRKAG3PRKAG3 isoform 1. (489 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
CNBD2CNBD2 isoform 3. (511 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PEX26Tubulin alpha-8 chain. (454 aa)
THAP7THAP domain containing 7. (309 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PPM1FPPM1F isoform 4. (454 aa)
CAMKVCaM kinase like vesicle associated. (501 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (547 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (837 aa)
TUBA3CTubulin alpha 3c. (450 aa)
GRIN3AGRIN3A isoform 1. (1115 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
GRIN1Glutamate receptor, ionotropic, N-methyl D-aspartate 1. (845 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PPM1EPPM1E isoform 1. (753 aa)
STK33Serine/threonine kinase 33. (514 aa)
PRKAR1AProtein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1). (381 aa)
LRBALRBA isoform 8. (747 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (921 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
GRIN3BGRIN3B isoform 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1043 aa)
TUBB8Tubulin beta chain-like. (424 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (548 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kineti [...] (1471 aa)
ENSPTRP00000056983annotation not available (477 aa)
GIT1G protein-coupled receptor kinase interacting ArfGAP 1. (770 aa)
PRKAR2BProtein kinase, cAMP-dependent, regulatory, type II, beta. (418 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
PRKYSerine/threonine-protein kinase PRKX. (358 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
TUBA3ETubulin, alpha 3e. (459 aa)
RPS6KA2Ribosomal protein S6 kinase alpha-2 isoform X1. (758 aa)
ERBB4Receptor protein-tyrosine kinase. (1386 aa)
ENSPTRP00000063748annotation not available (459 aa)
GRIN2DGRIN2D isoform 1. (1265 aa)
ERASES cell expressed Ras. (233 aa)
ADCY1-2Adenylate cyclase 1. (1119 aa)
ENSPTRP00000065686annotation not available (506 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (458 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
ENSPTRP00000067784annotation not available (357 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (853 aa)
PRKXProtein kinase, X-linked; Belongs to the protein kinase superfamily. (358 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (426 aa)
ENSPTRP00000071372annotation not available (243 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (519 aa)
ENSPTRP00000071983annotation not available (346 aa)
GRIN2CGRIN2C isoform 4. (1240 aa)
NBEANBEA isoform 7. (2947 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
NEFMNeurofilament medium; Belongs to the intermediate filament family. (903 aa)
TUBA4BTUBA4B isoform 1. (241 aa)
ENSPTRP00000074829annotation not available (385 aa)
CK820_G0016908LRBA isoform 14. (265 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (543 aa)
SRCTyrosine-protein kinase. (542 aa)
DCLK3Doublecortin like kinase 3. (817 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PAPLNPapilin, proteoglycan like sulfated glycoprotein. (1278 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
PRKAG2-2PRKAG2 isoform 10. (204 aa)
PRKAB2Protein kinase, AMP-activated, beta 2 non-catalytic subunit. (272 aa)
ACTN2ACTN2 isoform 2. (894 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PEX26-2Peroxisomal biogenesis factor 26. (454 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
CK820_G0051601TUBB3 isoform 13. (122 aa)
ENSPTRP00000083779annotation not available (309 aa)
LOC738663Tubulin beta-8 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Has a key role in meiotic spindle assembly and oocyte maturation (By similarity); Belongs to the tubulin family. (444 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
ENSPTRP00000084386annotation not available (503 aa)
ENSPTRP00000084437annotation not available (441 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
CAMK1Calcium/calmodulin-dependent protein kinase I; Belongs to the protein kinase superfamily. (380 aa)
ENSPTRP00000086254Microtubule-associated protein tau. (776 aa)
CK820_G0045118TUBB4A isoform 4; Belongs to the tubulin family. (407 aa)
LOC750209Tubulin beta-8 chain isoform X2. (435 aa)
ENSPTRP00000088150annotation not available (75 aa)
ENSPTRP00000088253annotation not available (118 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (446 aa)
ENSPTRP00000089644annotation not available (335 aa)
PRKAG2PRKAG2 isoform 4. (445 aa)
ENSPTRP00000090121annotation not available (331 aa)
PDPK13-phosphoinositide dependent protein kinase-1. (542 aa)
CK820_G0053542-2TUBB8 isoform 4. (119 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ENSPTRP00000091139annotation not available (114 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
PNCK-2Calcium/calmodulin-dependent protein kinase type 1B isoform X4. (343 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
NRG1NRG1 isoform 3. (713 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (532 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase II gamma. (562 aa)
ENSPTRP00000093238Tubulin beta-8 chain-like. (439 aa)
PRKAG1PRKAG1 isoform 12. (333 aa)
THAP6THAP domain containing 6. (222 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (16%) [HD]