22 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	DIS3L	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
	EXOSC6	Exosome complex component MTR3. (272 aa)
	ZFP36	Zinc finger protein 36, C3H type, homolog. (332 aa)
	EXOSC7	Exosome component 7. (291 aa)
	XRN1	5'-3' exoribonuclease 1. (1706 aa)
	TNPO1	TNPO1 isoform 1. (898 aa)
	EXOSC4	Exosome component 4. (245 aa)
	EXOSC3	Exosome complex exonuclease RRP40. (275 aa)
	TNPO2	TNPO2 isoform 2. (897 aa)
	DIS3L2	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (887 aa)
	DCP1A	DCP1 decapping enzyme homolog A. (582 aa)
	DCP2	DCP2 decapping enzyme homolog. (420 aa)
	EXOSC2-2	Exosome component 2. (293 aa)
	LOC749762	Transportin-1 pseudogene. (775 aa)
	EXOSC9	Exosome component 9. (456 aa)
	EXOSC8	Exosome component 8. (276 aa)
	DIS3	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	EXOSC1	Exosome component 1. (195 aa)
	EXOSC2	Exosome component 2. (293 aa)
	EXOSC5	Exosome component 5. (235 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCP1A	DCP2	ENSPTRP00000092316	ENSPTRP00000088791	DCP1 decapping enzyme homolog A.	DCP2 decapping enzyme homolog.	0.999
DCP1A	DIS3	ENSPTRP00000092316	ENSPTRP00000053467	DCP1 decapping enzyme homolog A.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.620
DCP1A	DIS3L	ENSPTRP00000092316	ENSPTRP00000012300	DCP1 decapping enzyme homolog A.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.557
DCP1A	DIS3L2	ENSPTRP00000092316	ENSPTRP00000042229	DCP1 decapping enzyme homolog A.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.557
DCP1A	EXOSC1	ENSPTRP00000092316	ENSPTRP00000050411	DCP1 decapping enzyme homolog A.	Exosome component 1.	0.592
DCP1A	EXOSC2	ENSPTRP00000092316	ENSPTRP00000048785	DCP1 decapping enzyme homolog A.	Exosome component 2.	0.560
DCP1A	EXOSC2-2	ENSPTRP00000092316	ENSPTRP00000074427	DCP1 decapping enzyme homolog A.	Exosome component 2.	0.560
DCP1A	EXOSC3	ENSPTRP00000092316	ENSPTRP00000035836	DCP1 decapping enzyme homolog A.	Exosome complex exonuclease RRP40.	0.599
DCP1A	EXOSC4	ENSPTRP00000092316	ENSPTRP00000035368	DCP1 decapping enzyme homolog A.	Exosome component 4.	0.660
DCP1A	EXOSC5	ENSPTRP00000092316	ENSPTRP00000048698	DCP1 decapping enzyme homolog A.	Exosome component 5.	0.675
DCP1A	EXOSC6	ENSPTRP00000092316	ENSPTRP00000014169	DCP1 decapping enzyme homolog A.	Exosome complex component MTR3.	0.574
DCP1A	EXOSC9	ENSPTRP00000092316	ENSPTRP00000062409	DCP1 decapping enzyme homolog A.	Exosome component 9.	0.598
DCP1A	XRN1	ENSPTRP00000092316	ENSPTRP00000026654	DCP1 decapping enzyme homolog A.	5'-3' exoribonuclease 1.	0.990
DCP1A	ZFP36	ENSPTRP00000092316	ENSPTRP00000018802	DCP1 decapping enzyme homolog A.	Zinc finger protein 36, C3H type, homolog.	0.635
DCP2	DCP1A	ENSPTRP00000088791	ENSPTRP00000092316	DCP2 decapping enzyme homolog.	DCP1 decapping enzyme homolog A.	0.999
DCP2	DIS3	ENSPTRP00000088791	ENSPTRP00000053467	DCP2 decapping enzyme homolog.	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.737
DCP2	DIS3L	ENSPTRP00000088791	ENSPTRP00000012300	DCP2 decapping enzyme homolog.	DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.	0.639
DCP2	DIS3L2	ENSPTRP00000088791	ENSPTRP00000042229	DCP2 decapping enzyme homolog.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...]	0.652
DCP2	EXOSC1	ENSPTRP00000088791	ENSPTRP00000050411	DCP2 decapping enzyme homolog.	Exosome component 1.	0.744
DCP2	EXOSC2	ENSPTRP00000088791	ENSPTRP00000048785	DCP2 decapping enzyme homolog.	Exosome component 2.	0.664