STRINGSTRING
SCUBE2 SCUBE2 SHH SHH DHH DHH NOTUM NOTUM ADAM17 ADAM17 IHH IHH GPC5 GPC5 DISP2 DISP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCUBE2SCUBE2 isoform 2. (996 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (496 aa)
ADAM17ADAM17 isoform 3. (999 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
GPC5GPC5 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
DISP2Dispatched RND transporter family member 2. (1401 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.