STRINGSTRING
BBS2 BBS2 RAB8A RAB8A CCT4 CCT4 BBS5 BBS5 PDE6D PDE6D MKKS MKKS MCHR1 MCHR1 PKDREJ PKDREJ LZTFL1 LZTFL1 ARF4 ARF4 ARL13B ARL13B RHO RHO NPHP3 NPHP3 PKD2 PKD2 BBS7 BBS7 BBS12 BBS12 EXOC3 EXOC3 CCT5 CCT5 EXOC2 EXOC2 TCP1 TCP1 SMO SMO EXOC4 EXOC4 CNGB3 CNGB3 ASAP1 ASAP1 RP2 RP2 CNGA2 CNGA2 GBF1 GBF1 EXOC1 EXOC1 RAB11FIP3 RAB11FIP3 PKD2L2 PKD2L2 MYOT MYOT CNGA4 CNGA4 CCT8L2 CCT8L2 CCT3 CCT3 CYS1 CYS1 BBS4 BBS4 ENSPTRP00000061551 ENSPTRP00000061551 EXOC7 EXOC7 PKD1L1 PKD1L1 CK820_G0056924 CK820_G0056924 ENSPTRP00000064921 ENSPTRP00000064921 PKD1L3 PKD1L3 TTC8 TTC8 ENSPTRP00000066718 ENSPTRP00000066718 ASAP3 ASAP3 SMO-2 SMO-2 PKD1L1-2 PKD1L1-2 SSTR3 SSTR3 ENSPTRP00000093266 ENSPTRP00000093266 CCT8L2-2 CCT8L2-2 CCT8 CCT8 INPP5E INPP5E EXOC6B EXOC6B ENSPTRP00000085241 ENSPTRP00000085241 BBS9 BBS9 ASAP2 ASAP2 CK820_G0054628 CK820_G0054628 EXOC6 EXOC6 ARL3 ARL3 RAB11A RAB11A EXOC5 EXOC5 CNGA2-2 CNGA2-2 ENSPTRP00000077287 ENSPTRP00000077287 LOC743586 LOC743586 CCT2 CCT2 ARL6 ARL6 ENSPTRP00000075146 ENSPTRP00000075146 CNGB1 CNGB1 EXOC8 EXOC8 PKD2L1 PKD2L1 BBS1 BBS1 RAB3IP RAB3IP BBS10 BBS10 UNC119B UNC119B EXOC3L1 EXOC3L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
CCT4T-complex protein 1 subunit delta. (544 aa)
BBS5T0004560 isoform 1. (341 aa)
PDE6DRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (150 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
MCHR1Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. (422 aa)
PKDREJPolycystin family receptor for egg jelly. (2251 aa)
LZTFL1Leucine zipper transcription factor-like 1. (299 aa)
ARF4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
RHORhodopsin. (348 aa)
NPHP3NPHP3 isoform 6. (1330 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (968 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
BBS12BBS12 isoform 1. (710 aa)
EXOC3Aryl-hydrocarbon receptor repressor. (749 aa)
CCT5Chaperonin containing TCP1, subunit 5 (Epsilon). (541 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
TCP1T-complex protein 1 subunit alpha. (556 aa)
SMOSMO isoform 1; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
EXOC4Exocyst complex component 4. (974 aa)
CNGB3CNGB3 isoform 2. (809 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
RP2Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (350 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
EXOC1Exocyst complex component 1. (901 aa)
RAB11FIP3RAB11 family interacting protein 3 (Class II). (734 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (624 aa)
MYOTMYOT isoform 4. (498 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
CCT8L2LOW QUALITY PROTEIN: putative T-complex protein 1 subunit theta-like 1. (557 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
CYS1CYS1 isoform 2. (158 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
ENSPTRP00000061551annotation not available (394 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa)
PKD1L1PKD1L1 isoform 1. (2857 aa)
CK820_G0056924NPIPA2 isoform 1. (277 aa)
ENSPTRP00000064921annotation not available (544 aa)
PKD1L3Polycystin 1 like 3, transient receptor potential channel interacting. (1732 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
ENSPTRP00000066718annotation not available (607 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (905 aa)
SMO-2Smoothened, frizzled class receptor. (786 aa)
PKD1L1-2Polycystin 1 like 1, transient receptor potential channel interacting. (2857 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa)
ENSPTRP00000093266annotation not available (417 aa)
CCT8L2-2T-complex protein 1 subunit theta-like 2. (557 aa)
CCT8Chaperonin containing TCP1, subunit 8 (Theta). (548 aa)
INPP5EPhosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate(PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity). Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (By similarity); Belongs to the inos [...] (626 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
ENSPTRP00000085241annotation not available (93 aa)
BBS9Bardet-Biedl syndrome 9. (887 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (1006 aa)
CK820_G0054628PKD1 isoform 4. (3384 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (785 aa)
ARL3ADP-ribosylation factor-like 3; Belongs to the small GTPase superfamily. Arf family. (151 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
EXOC5Exocyst complex component 5. (711 aa)
CNGA2-2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
ENSPTRP00000077287annotation not available (417 aa)
LOC743586T-complex protein 1 subunit alpha pseudogene. (338 aa)
CCT2Chaperonin containing TCP1, subunit 2 (Beta). (535 aa)
ARL6ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (203 aa)
ENSPTRP00000075146annotation not available (457 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (1251 aa)
EXOC8Exocyst complex component 8. (725 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (805 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (593 aa)
RAB3IPT0146196 isoform 1. (395 aa)
BBS10Bardet-Biedl syndrome 10. (723 aa)
UNC119BUnc-119 lipid binding chaperone B. (251 aa)
EXOC3L1Exocyst complex component 3 like 1. (746 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.