Your Input: | |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (429 aa) |
| | PRKAG1 | PRKAG1 isoform 12. (333 aa) |
| | ENSPTRP00000092743 | annotation not available (379 aa) |
| | C17H17orf113 | Chromosome 17 C17orf113 homolog. (675 aa) |
| | WRN | WRN RecQ like helicase. (1446 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma. (421 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase-1. (542 aa) |
| | CSNK2A1 | Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily. (391 aa) |
| | PRKAG2 | PRKAG2 isoform 4. (445 aa) |
| | CSNK2B | LY6G5B isoform 1. (298 aa) |
| | CK820_G0024820 | PPP2R5C isoform 26. (479 aa) |
| | ENSPTRP00000089693 | annotation not available (226 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | RFFL | E3 ubiquitin-protein ligase rififylin isoform X2. (363 aa) |
| | BRD1 | Bromodomain containing 1. (1189 aa) |
| | MRE11 | MRE11 isoform 6; Belongs to the MRE11/RAD32 family. (762 aa) |
| | BRD9 | BRD9 isoform 8. (600 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | TPX2 | TPX2, microtubule-associated, homolog. (728 aa) |
| | PRKAG3 | PRKAG3 isoform 1. (489 aa) |
| | RPS27A | RPS27A isoform 1. (156 aa) |
| | AURKC | AURKC isoform 1; Belongs to the protein kinase superfamily. (309 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (828 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (634 aa) |
| | TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa. (862 aa) |
| | ENSPTRP00000062267 | annotation not available (413 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (339 aa) |
| | ENSPTRP00000061528 | annotation not available (854 aa) |
| | ATRIP | ATR interacting protein. (791 aa) |
| | PLK5 | PLK5 isoform 3. (337 aa) |
| | TAF15 | TAF15 isoform 12. (603 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase, type II, beta. (416 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1249 aa) |
| | CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (307 aa) |
| | MBD3L1 | Methyl-CpG binding domain protein 3 like 1. (194 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | ENSPTRP00000086815 | annotation not available (145 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | ENSPTRP00000088036 | annotation not available (243 aa) |
| | L3MBTL4 | L3MBTL4 isoform 6. (623 aa) |
| | PHF20 | PHD finger protein 20. (1012 aa) |
| | L3MBTL1 | T0068992 isoform 1. (840 aa) |
| | AURKA | Serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (403 aa) |
| | CK820_G0037203 | TAF4 isoform 5. (635 aa) |
| | AIRE | Autoimmune regulator. (545 aa) |
| | EP300 | E1A binding protein p300. (2175 aa) |
| | PRR5 | Proline-rich protein 5 isoform X2. (411 aa) |
| | TOPBP1 | Topoisomerase (DNA) II binding protein 1. (1522 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | CCNA2 | CCNA2 isoform 1; Belongs to the cyclin family. (432 aa) |
| | POU4F2 | POU domain protein. (406 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | LOC738370 | Bromodomain containing 9. (596 aa) |
| | RAD1 | RAD1 isoform 1. (282 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (681 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (988 aa) |
| | SLF1 | SLF1 isoform 2. (1058 aa) |
| | RAD50 | T0093306 isoform 4. (1312 aa) |
| | ENSPTRP00000029492 | annotation not available (223 aa) |
| | POU4F3 | POU domain, class 4, transcription factor 3. (338 aa) |
| | CCNG1 | CCNG1 isoform 2; Belongs to the cyclin family. (295 aa) |
| | DAXX | Death domain associated protein. (742 aa) |
| | TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa. (211 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] (360 aa) |
| | PRDM1 | PR/SET domain 1. (825 aa) |
| | TBPL1 | TATA box-binding protein-like protein 1. (186 aa) |
| | RPA3 | Replication protein A3, 14kDa. (121 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | RFC2 | Replication factor C (Activator 1) 2, 40kDa. (354 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2002 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | TP53INP1 | TP53INP1 isoform 1. (240 aa) |
| | RMI1 | RMI1, RecQ mediated genome instability 1, homolog. (625 aa) |
| | MAPKAP1 | Mitogen-activated protein kinase associated protein 1. (522 aa) |
| | TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa. (124 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (895 aa) |
| | NOC2L | NOC2L isoform 4. (745 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (986 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (291 aa) |
| | TOP3A | DNA topoisomerase III alpha. (1001 aa) |
| | TAF9B | TAF9B isoform 1. (251 aa) |
| | RBBP7 | RBBP7 isoform 5. (469 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | CK820_G0053530 | EHMT1 isoform 4. (1100 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (581 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1267 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | UBC | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (693 aa) |
| | ATR | Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | SMYD2 | SET and MYND domain containing 2. (433 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | ZNF385B | Zinc finger protein 385B. (471 aa) |
| | ZNF385A | Zinc finger protein 385A. (414 aa) |
| | ENSPTRP00000082174 | annotation not available (558 aa) |
| | BRD7 | Bromodomain containing 7. (652 aa) |
| | ENSPTRP00000081300 | annotation not available (154 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) |
| | ENSPTRP00000080780 | annotation not available (683 aa) |
| | ENSPTRP00000080278 | annotation not available (136 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (457 aa) |
| | CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (311 aa) |
| | ENSPTRP00000080206 | annotation not available (395 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (201 aa) |
| | LOC460817 | Bromodomain-containing protein 7 pseudogene. (397 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) |
| | PRKAB2 | Protein kinase, AMP-activated, beta 2 non-catalytic subunit. (272 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1137 aa) |
| | ENSPTRP00000078047 | annotation not available (132 aa) |
| | PRKAG2-2 | PRKAG2 isoform 10. (204 aa) |
| | ENSPTRP00000077224 | annotation not available (84 aa) |
| | RECQL4 | RECQL4 isoform 3. (1208 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | ENSPTRP00000076134 | annotation not available (211 aa) |
| | AKT1 | AKT1 isoform 3; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSPTRP00000082945 | annotation not available (603 aa) |
| | ENSPTRP00000083257 | annotation not available (412 aa) |
| | PPP2R1A | Protein phosphatase 2, regulatory subunit A, alpha. (637 aa) |
| | CHD4 | Chromodomain helicase DNA binding protein 4. (1912 aa) |
| | RFC2-2 | Replication factor C subunit 2. (354 aa) |
| | TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa. (255 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (526 aa) |
| | ENSPTRP00000085589 | annotation not available (393 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | FOXP4-2 | Forkhead box P4. (668 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1121 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (777 aa) |
| | ENSPTRP00000074557 | annotation not available (88 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | BRPF1 | Bromodomain and PHD finger containing, 1. (1253 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1955 aa) |
| | ENSPTRP00000073552 | annotation not available (162 aa) |
| | AURKB-2 | Aurora kinase B. (344 aa) |
| | ENSPTRP00000072489 | annotation not available (673 aa) |
| | ING1 | Inhibitor of growth protein. (421 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha. (406 aa) |
| | ENSPTRP00000072038 | annotation not available (369 aa) |
| | ENSPTRP00000071568 | annotation not available (98 aa) |
| | HUS1-2 | HUS1 checkpoint clamp component. (273 aa) |
| | ING5 | Inhibitor of growth family member 5. (254 aa) |
| | CCNA1 | CCNA1 isoform 3; Belongs to the cyclin family. (421 aa) |
| | LOC100613237 | BANP isoform 5. (455 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa) |
| | MLST8 | MLST8 isoform 3. (327 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | ENSPTRP00000069476 | annotation not available (708 aa) |
| | ENSPTRP00000069077 | annotation not available (82 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | PHF20-2 | PHD finger protein 20. (103 aa) |
| | KMT5A | [histone H4]-lysine20 N-methyltransferase SETD8. (199 aa) |
| | RFC4 | Replication factor C (Activator 1) 4, 37kDa. (363 aa) |
| | SETD9 | Chromosome 5 open reading frame 35. (299 aa) |
| | CHEK2 | Checkpoint kinase 2. (586 aa) |
| | ENSPTRP00000067636 | annotation not available (84 aa) |
| | SETD8 | SET domain containing (Lysine methyltransferase) 8. (334 aa) |
| | CHEK1 | CHEK1 isoform 10. (485 aa) |
| | ENSPTRP00000067263 | Ubiquitin-large subunit ribosomal protein L40e. (119 aa) |
| | LOC748850 | HDAC2 isoform 9. (445 aa) |
| | CDK2 | CDK2 isoform 4; Belongs to the protein kinase superfamily. (346 aa) |
| | LINC02218 | Long intergenic non-protein coding RNA 2218. (198 aa) |
| | DYRK2 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (601 aa) |
| | ENSPTRP00000065307 | annotation not available (623 aa) |
| | MTA2 | Metastasis associated 1 family, member 2. (673 aa) |
| | MAPKAPK5 | Mitogen-activated protein kinase-activated protein kinase 5. (487 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (803 aa) |
| | DNA2 | DNA2 isoform 3. (1024 aa) |
| | RAD50-2 | RAD50 double strand break repair protein. (1312 aa) |
| | PPP2CA | PPP2CB isoform 8. (309 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (714 aa) |
| | TP53RK | TP53 regulating kinase. (253 aa) |
| | FOXP4 | FOXP4 isoform 3. (668 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (499 aa) |
| | BRPF3 | Bromodomain and PHD finger containing, 3. (1205 aa) |
| | ENSPTRP00000082766 | annotation not available (412 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa. (213 aa) |
| | POU4F1 | POU domain protein. (350 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (673 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | HIPK1 | HIPK1 isoform 10. (1210 aa) |
| | GATAD2B | GATAD2B isoform 3. (593 aa) |
| | NUAK2 | NUAK2 isoform 1. (672 aa) |
| | DYRK3 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3. (588 aa) |
| | EXO1 | EXO1 isoform 1. (846 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (931 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (605 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (238 aa) |
| | DYRK4 | T0131183 isoform 1. (634 aa) |
| | NUAK1 | NUAK family, SNF1-like kinase, 1. (661 aa) |
| | RFC5 | Replication factor C (Activator 1) 5, 36.5kDa. (340 aa) |
| | PRKAB1 | Protein kinase, AMP-activated, beta 1 non-catalytic subunit. (270 aa) |
| | RFC3 | Replication factor C (Activator 1) 3, 38kDa. (356 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | PPP1R13B | Protein phosphatase 1, regulatory (Inhibitor) subunit 13B. (1090 aa) |
| | PML | PML isoform 6. (836 aa) |
| | BLM | BLM isoform 1. (1417 aa) |
| | MEIOB | MEIOB isoform 2. (471 aa) |
| | RMI2 | Chromosome 16 open reading frame 75. (147 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2058 aa) |
| | AURKB | AURKB isoform 1; Belongs to the protein kinase superfamily. (344 aa) |
| | TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa. (1199 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | BANP | BTG3 associated nuclear protein. (519 aa) |
| | CSNK2A2 | Casein kinase 2, alpha prime polypeptide; Belongs to the protein kinase superfamily. (350 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | ZNF385C | Zinc finger protein 385C. (499 aa) |
| | TBP | TBP isoform 1. (336 aa) |
| | RNF34 | Ring finger protein 34. (500 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1083 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | KXD1 | UBA52 isoform 10. (231 aa) |
| | ENSPTRP00000060412 | annotation not available (156 aa) |
