STRINGSTRING
GRB2 GRB2 ACTRT2 ACTRT2 ACTL8 ACTL8 WASF2 WASF2 ENSPTRP00000000715 ENSPTRP00000000715 ARPC5 ARPC5 CK820_G0023253 CK820_G0023253 NCKAP1L NCKAP1L CYFIP1 CYFIP1 ENSPTRP00000016618 ENSPTRP00000016618 NCKAP1 NCKAP1 MAPK1 MAPK1 BRK1 BRK1 NCKIPSD NCKIPSD NCK1 NCK1 WIPF3 WIPF3 ARPC1A ARPC1A ARPC1B ARPC1B WASL WASL ACTR3B ACTR3B CK820_G0053598 CK820_G0053598 ACTL7B ACTL7B ACTL7A ACTL7A ARPC5L ARPC5L BTK BTK ACTRT1 ACTRT1 WASF3 WASF3 ABI1 ABI1 WASF1 WASF1 LOC744297 LOC744297 LOC456647 LOC456647 MAPK3 MAPK3 CK820_G0015929 CK820_G0015929 ACTB ACTB ACTL9 ACTL9 CK820_G0012168 CK820_G0012168 FMN1 FMN1 WIPF2 WIPF2 ACTR3C ACTR3C CYFIP2 CYFIP2 ENSPTRP00000064849 ENSPTRP00000064849 BAIAP2 BAIAP2 ENSPTRP00000066583 ENSPTRP00000066583 WAS WAS RAC1 RAC1 ENSPTRP00000070693 ENSPTRP00000070693 ENSPTRP00000070878 ENSPTRP00000070878 ENSPTRP00000072166 ENSPTRP00000072166 ENSPTRP00000072507 ENSPTRP00000072507 FMN2 FMN2 ABL1 ABL1 ABI2 ABI2 ARPC3 ARPC3 WIPF1 WIPF1 CDC42 CDC42 ENSPTRP00000077947 ENSPTRP00000077947 CK820_G0023066 CK820_G0023066 ENSPTRP00000078387 ENSPTRP00000078387 ENSPTRP00000078893 ENSPTRP00000078893 ENSPTRP00000079105 ENSPTRP00000079105 ACTG1 ACTG1 ENSPTRP00000080740 ENSPTRP00000080740 ENSPTRP00000081694 ENSPTRP00000081694 ENSPTRP00000081707 ENSPTRP00000081707 CK820_G0012542 CK820_G0012542 PTK2 PTK2 RAC1-2 RAC1-2 ARPC4 ARPC4 ENSPTRP00000085141 ENSPTRP00000085141 ENSPTRP00000085830 ENSPTRP00000085830 ARPC2 ARPC2 ENSPTRP00000090995 ENSPTRP00000090995 ENSPTRP00000091405 ENSPTRP00000091405 WAS-2 WAS-2 ACTR2 ACTR2 ENSPTRP00000093517 ENSPTRP00000093517
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor-bound protein 2. (217 aa)
ACTRT2ACTRT2 isoform 1; Belongs to the actin family. (377 aa)
ACTL8ACTL8 isoform 1; Belongs to the actin family. (366 aa)
WASF2WAS protein family, member 2. (498 aa)
ENSPTRP00000000715Wiskott-Aldrich syndrome protein family member 2-like. (492 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CK820_G0023253FMN2 isoform 2. (1196 aa)
NCKAP1LNCK associated protein 1 like. (1127 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ENSPTRP00000016618Actin beta like 2. (375 aa)
NCKAP1Nck-associated protein 1. (1128 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
NCK1Cytoplasmic protein. (377 aa)
WIPF3WAS/WASL interacting protein family member 3. (483 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
ARPC1BActin related protein 2/3 complex, subunit 1A/1B. (372 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
ACTR3BARP3 actin-related protein 3 homolog B; Belongs to the actin family. (418 aa)
CK820_G0053598POTEJ isoform 1; Belongs to the actin family. (1078 aa)
ACTL7BActin-like protein 7B; Belongs to the actin family. (415 aa)
ACTL7AActin-like protein 7A; Belongs to the actin family. (435 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
BTKBTK isoform 2. (693 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (376 aa)
WASF3WH2 domain-containing protein. (502 aa)
ABI1Abl interactor 1. (508 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
LOC744297POTE ankyrin domain family member G-like. (956 aa)
LOC456647WASHC1 isoform 1. (323 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CK820_G0015929ARPC3 isoform 3. (178 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (378 aa)
ACTL9ACTL9 isoform 1; Belongs to the actin family. (416 aa)
CK820_G0012168ABL1 isoform 3. (1149 aa)
FMN1FMN1 isoform 1. (1425 aa)
WIPF2WAS/WASL interacting protein family, member 2. (440 aa)
ACTR3CActin-related protein 3C isoform X1. (239 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ENSPTRP00000064849annotation not available (150 aa)
BAIAP2BAI1 associated protein 2. (553 aa)
ENSPTRP00000066583annotation not available (181 aa)
WASWAS isoform 1. (502 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (220 aa)
ENSPTRP00000070693annotation not available (228 aa)
ENSPTRP00000070878annotation not available (324 aa)
ENSPTRP00000072166annotation not available (318 aa)
ENSPTRP00000072507annotation not available (659 aa)
FMN2FMN2 isoform 6. (198 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ABI2Abl interactor 2. (513 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
WIPF1WAS/WASL interacting protein family, member 1. (554 aa)
CDC42Cell division cycle 42 (GTP binding protein, 25kDa). (191 aa)
ENSPTRP00000077947annotation not available (48 aa)
CK820_G0023066ACTA1 isoform 2. (150 aa)
ENSPTRP00000078387annotation not available (202 aa)
ENSPTRP00000078893annotation not available (168 aa)
ENSPTRP00000079105annotation not available (149 aa)
ACTG1ACTG1 isoform 13. (375 aa)
ENSPTRP00000080740annotation not available (150 aa)
ENSPTRP00000081694annotation not available (182 aa)
ENSPTRP00000081707annotation not available (149 aa)
CK820_G0012542ACTR3 isoform 5. (34 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1113 aa)
RAC1-2Rac family small GTPase 1. (212 aa)
ARPC4Actin-related protein 2/3 complex subunit 4 isoform X4. (173 aa)
ENSPTRP00000085141annotation not available (333 aa)
ENSPTRP00000085830annotation not available (168 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
ENSPTRP00000090995annotation not available (206 aa)
ENSPTRP00000091405annotation not available (334 aa)
WAS-2WASP actin nucleation promoting factor. (502 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSPTRP00000093517annotation not available (149 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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