44 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CPSF2	Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
	PAPOLA	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
	NUDT21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
	CPSF4L	Cleavage and polyadenylation specific factor 4 like. (179 aa)
	ZNF473	Zinc finger protein 473. (871 aa)
	CPSF3	Cleavage and polyadenylation specificity factor 73 kDa subunit. (684 aa)
	WDR33	WD repeat domain 33. (1336 aa)
	CSTF1	Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa. (431 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
	LSM11	LSM11, U7 small nuclear RNA associated. (338 aa)
	CPSF4	Cleavage and polyadenylation specific factor 4, 30kDa. (269 aa)
	NCBP1	Nuclear cap binding protein subunit 1, 80kDa. (790 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
	CLP1	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
	SNRPB	Small nuclear ribonucleoprotein polypeptides B and B1. (289 aa)
	CPSF1	CPSF1 isoform 10. (1467 aa)
	SYMPK	SYMPK isoform 3. (1310 aa)
	LOC107969647	Small nuclear ribonucleoprotein E pseudogene. (83 aa)
	ENSPTRP00000066562	annotation not available (84 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
	CSTF2	Cleavage stimulation factor subunit 2. (597 aa)
	CK820_G0015337	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (68 aa)
	CPSF1-2	Cleavage and polyadenylation specific factor 1, 160kDa. (1442 aa)
	SNRPF-2	Small nuclear ribonucleoprotein polypeptide F. (78 aa)
	ENSPTRP00000077950	annotation not available (67 aa)
	ENSPTRP00000078900	annotation not available (71 aa)
	CK820_G0008138	CSTF2T isoform 1. (302 aa)
	BCL2L2	BCL2L2 isoform 2. (333 aa)
	NCBP2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (148 aa)
	ENSPTRP00000082994	annotation not available (74 aa)
	SNRPG-2	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
	ENSPTRP00000086779	annotation not available (250 aa)
	SLBP	Histone RNA hairpin-binding protein. (272 aa)
	FIP1L1	Pre-mRNA 3'-end-processing factor FIP1 isoform X1. (603 aa)
	ENSPTRP00000091185	annotation not available (277 aa)
	ENSPTRP00000091616	annotation not available (183 aa)
	PAPOLB	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (687 aa)
	ENSPTRP00000093260	annotation not available (603 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	CSTF3	Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa. (717 aa)
	CPSF7	CPSF7 isoform 1. (471 aa)
	PCF11	PCF11, cleavage and polyadenylation factor subunit, homolog. (1686 aa)
	CPSF6	CPSF6 isoform 3. (589 aa)
	SNRPF	Small nuclear ribonucleoprotein polypeptide F. (127 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L2	CK820_G0008138	ENSPTRP00000080265	ENSPTRP00000079530	BCL2L2 isoform 2.	CSTF2T isoform 1.	0.748
BCL2L2	CLP1	ENSPTRP00000080265	ENSPTRP00000062766	BCL2L2 isoform 2.	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	0.523
BCL2L2	CPSF1	ENSPTRP00000080265	ENSPTRP00000063855	BCL2L2 isoform 2.	CPSF1 isoform 10.	0.478
BCL2L2	CPSF1-2	ENSPTRP00000080265	ENSPTRP00000075129	BCL2L2 isoform 2.	Cleavage and polyadenylation specific factor 1, 160kDa.	0.478
BCL2L2	CPSF2	ENSPTRP00000080265	ENSPTRP00000011335	BCL2L2 isoform 2.	Cleavage and polyadenylation specificity factor subunit 2.	0.604
BCL2L2	CPSF3	ENSPTRP00000080265	ENSPTRP00000020015	BCL2L2 isoform 2.	Cleavage and polyadenylation specificity factor 73 kDa subunit.	0.596
BCL2L2	CPSF4	ENSPTRP00000080265	ENSPTRP00000033281	BCL2L2 isoform 2.	Cleavage and polyadenylation specific factor 4, 30kDa.	0.539
BCL2L2	CPSF4L	ENSPTRP00000080265	ENSPTRP00000016303	BCL2L2 isoform 2.	Cleavage and polyadenylation specific factor 4 like.	0.516
BCL2L2	CPSF6	ENSPTRP00000080265	ENSPTRP00000008836	BCL2L2 isoform 2.	CPSF6 isoform 3.	0.558
BCL2L2	CPSF7	ENSPTRP00000080265	ENSPTRP00000006436	BCL2L2 isoform 2.	CPSF7 isoform 1.	0.484
BCL2L2	CSTF1	ENSPTRP00000080265	ENSPTRP00000023478	BCL2L2 isoform 2.	Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa.	0.636
BCL2L2	CSTF2	ENSPTRP00000080265	ENSPTRP00000067955	BCL2L2 isoform 2.	Cleavage stimulation factor subunit 2.	0.729
BCL2L2	CSTF3	ENSPTRP00000080265	ENSPTRP00000006051	BCL2L2 isoform 2.	Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa.	0.600
BCL2L2	ENSPTRP00000091616	ENSPTRP00000080265	ENSPTRP00000091616	BCL2L2 isoform 2.	annotation not available	0.478
BCL2L2	ENSPTRP00000093260	ENSPTRP00000080265	ENSPTRP00000093260	BCL2L2 isoform 2.	annotation not available	0.633
BCL2L2	FIP1L1	ENSPTRP00000080265	ENSPTRP00000090492	BCL2L2 isoform 2.	Pre-mRNA 3'-end-processing factor FIP1 isoform X1.	0.633
BCL2L2	NCBP1	ENSPTRP00000080265	ENSPTRP00000061531	BCL2L2 isoform 2.	Nuclear cap binding protein subunit 1, 80kDa.	0.705
BCL2L2	NCBP2	ENSPTRP00000080265	ENSPTRP00000080568	BCL2L2 isoform 2.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.705
BCL2L2	NUDT21	ENSPTRP00000080265	ENSPTRP00000013877	BCL2L2 isoform 2.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.617
BCL2L2	PAPOLA	ENSPTRP00000080265	ENSPTRP00000011429	BCL2L2 isoform 2.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.707